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Maria Luisa De Giorgi
Department of Mathematics and Physics “Ennio De Giorgi”, University of Salento, 73100 Lecce, Italy

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Journal article
Published: 09 August 2021 in Nanomaterials
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Over the last decades, several materials have been proposed for the fabrication of dental and mandibular prosthetic implants. Today, the poly(methyl-methacrylate) (PMMA) resin is the most spread material, due to its ease of processing, low cost, aesthetic properties, low weight, biocompatibility, and biostability in the oral cavity. However, the porous surface (which favors the adhesion of microorganisms) and the weak mechanical properties (which lead to wear or fracture) are the major concerns. The inclusion of engineered nanomaterials in the acrylic matrix could improve the performances of PMMA. In this study, we added two different kind of nanomaterials, namely titanium dioxide nanoparticles (TiO2NPs) and halloysite clay nanotubes (HNTs) at two concentrations (1% and 3% w/w) in PMMA. Then, we assessed the effect of nanomaterials inclusion by the evaluation of specific physical parameters: Young’s modulus, roughness, and wettability. In addition, we investigated the potential beneficial effects regarding the Candida albicans (C. albicans) colonization reduction, the most common yeast responsible of several infections in oral cavity. Our experimental results showed an improvement of PMMA performance, following the addition of TiO2NPs and HNTs, in a dose dependent manner. In particular, the presence of TiO2NPs in the methacrylate matrix induced a greater increase in PMMA stiffness respect to HNTs addition. On the other hand, HNTs reduced the rate of C. albicans colonization more significantly than TiO2NPs. The results obtained are of great interest for the improvement of PMMA physico-chemical properties, in view of its possible application in clinical dentistry.

ACS Style

MariaFrancesca Cascione; Valeria De Matteis; Paolo Pellegrino; Giovanni Albanese; Maria De Giorgi; Fabio Paladini; Massimo Corsalini; Rosaria Rinaldi. Improvement of PMMA Dental Matrix Performance by Addition of Titanium Dioxide Nanoparticles and Clay Nanotubes. Nanomaterials 2021, 11, 2027 .

AMA Style

MariaFrancesca Cascione, Valeria De Matteis, Paolo Pellegrino, Giovanni Albanese, Maria De Giorgi, Fabio Paladini, Massimo Corsalini, Rosaria Rinaldi. Improvement of PMMA Dental Matrix Performance by Addition of Titanium Dioxide Nanoparticles and Clay Nanotubes. Nanomaterials. 2021; 11 (8):2027.

Chicago/Turabian Style

MariaFrancesca Cascione; Valeria De Matteis; Paolo Pellegrino; Giovanni Albanese; Maria De Giorgi; Fabio Paladini; Massimo Corsalini; Rosaria Rinaldi. 2021. "Improvement of PMMA Dental Matrix Performance by Addition of Titanium Dioxide Nanoparticles and Clay Nanotubes." Nanomaterials 11, no. 8: 2027.

Journal article
Published: 19 July 2021 in Cancers
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Background: In recent decades, gold nanoparticle (Au NP)-based cancer therapy has been heavily debated. The physico-chemical properties of AuNPs can be exploited in photothermal therapy, making them a powerful tool for selectively killing cancer cells. However, the synthetic side products and capping agents often induce a strong activation of the inflammatory pathways of macrophages, thus limiting their further applications in vivo. Methods: Here, we described a green method to obtain stable polyphenol-capped AuNPs (Au [email protected]), as polyphenols are known for their anti-inflammatory and anticancer properties. These NPs were used in human macrophages to test key inflammation-related markers, such as NF-κB, TNF-α, and interleukins-6 and 8. The results were compared with similar NPs obtained by a traditional chemical route (without the polyphenol coating), proving the potential of Au [email protected] to strongly promote the shutdown of inflammation. This was useful in developing them for use as heat-synergized tools in the thermal treatment of two types of cancer cells, namely, breast cancer (MCF-7) and neuroblastoma (SH-SY5Y) cells. The cell viability, calcium release, oxidative stress, HSP-70 expression, mitochondrial, and DNA damage, as well as cytoskeleton alteration, were evaluated. Results: Our results clearly demonstrate that the combined strategy markedly exerts anticancer effects against the tested cancer cell, while neither of the single treatments (only heat or only NPs) induced significant changes. Conclusions: Au [email protected] may be powerful agents in cancer treatment.

ACS Style

Valeria De Matteis; MariaFrancesca Cascione; Loris Rizzello; Daniela Manno; Claudia Di Guglielmo; Rosaria Rinaldi. Synergistic Effect Induced by Gold Nanoparticles with Polyphenols Shell during Thermal Therapy: Macrophage Inflammatory Response and Cancer Cell Death Assessment. Cancers 2021, 13, 3610 .

AMA Style

Valeria De Matteis, MariaFrancesca Cascione, Loris Rizzello, Daniela Manno, Claudia Di Guglielmo, Rosaria Rinaldi. Synergistic Effect Induced by Gold Nanoparticles with Polyphenols Shell during Thermal Therapy: Macrophage Inflammatory Response and Cancer Cell Death Assessment. Cancers. 2021; 13 (14):3610.

Chicago/Turabian Style

Valeria De Matteis; MariaFrancesca Cascione; Loris Rizzello; Daniela Manno; Claudia Di Guglielmo; Rosaria Rinaldi. 2021. "Synergistic Effect Induced by Gold Nanoparticles with Polyphenols Shell during Thermal Therapy: Macrophage Inflammatory Response and Cancer Cell Death Assessment." Cancers 13, no. 14: 3610.

Journal article
Published: 01 June 2021 in Nanomaterials
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Lead halide perovskites are emerging as extremely interesting active materials for a wide variety of optoelectronic and photonic devices. A deep understanding of their photophysics is thus fundamental in order to properly understand the origins of the materials active properties and to provide strategies for improving them. In this work, we exploit the local morphological variations in a drop-cast thin CsPbBr3 nanocrystal film to show that the aggregation of NCs has strong effects on the peak wavelengths of PL spectra, the linewidth, and the intensity of dependence on temperature. An analysis based on models that are frequently used in the literature led to completely different conclusions about the intrinsic NC emission properties extracted from spectra measured in points with different contribution of the PL from the aggregates. Our results demonstrate that extreme care has to be used in order to correctly correlate the spectral PL features with the intrinsic emission properties of lead halide perovskite NC films.

ACS Style

Marco Anni; Arianna Cretí; Maria De Giorgi; Mauro Lomascolo. Local Morphology Effects on the Photoluminescence Properties of Thin CsPbBr3 Nanocrystal Films. Nanomaterials 2021, 11, 1470 .

AMA Style

Marco Anni, Arianna Cretí, Maria De Giorgi, Mauro Lomascolo. Local Morphology Effects on the Photoluminescence Properties of Thin CsPbBr3 Nanocrystal Films. Nanomaterials. 2021; 11 (6):1470.

Chicago/Turabian Style

Marco Anni; Arianna Cretí; Maria De Giorgi; Mauro Lomascolo. 2021. "Local Morphology Effects on the Photoluminescence Properties of Thin CsPbBr3 Nanocrystal Films." Nanomaterials 11, no. 6: 1470.

Journal article
Published: 13 May 2021 in Molecules
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Noble metals nanoparticles (NPs) and metal oxide NPs are widely used in different fields of application and commercial products, exposing living organisms to their potential adverse effects. Recent evidences suggest their presence in the aquifers water and consequently in drinking water. In this work, we have carefully synthesized four types of NPs, namely, silver and gold NPs (Ag NPs and Au NPs) and silica and titanium dioxide NPs (SiO2 NPs and TiO2 NPs) having a similar size and negatively charged surfaces. The synthesis of Ag NPs and Au NPs was carried out by colloidal route using silver nitrate (AgNO3) and tetrachloroauric (III) acid (HAuCl4) while SiO2 NPs and TiO2 NPs were achieved by ternary microemulsion and sol-gel routes, respectively. Once the characterization of NPs was carried out in order to assess their physico-chemical properties, their impact on living cells was studied. We used the human colorectal adenocarcinoma cells (Caco-2), known as the best representative intestinal epithelial barrier model to understand the effects triggered by NPs through ingestion. Then, we moved to explore how water contamination caused by NPs can be lowered by the ability of three species of aquatic moss, namely, Leptodictyum riparium, Vesicularia ferriei, and Taxiphyllum barbieri, to absorb them. The experiments were conducted using two concentrations of NPs (100 μM and 500 Μm as metal content) and two time points (24 h and 48 h), showing a capture rate dependent on the moss species and NPs type. Then, the selected moss species, able to actively capture NPs, appear as a powerful tool capable to purify water from nanostructured materials, and then, to reduce the toxicity associated to the ingestion of contaminated drinking water.

ACS Style

Valeria De Matteis; Makarena Rojas; MariaFrancesca Cascione; Stefano Mazzotta; Gian Di Sansebastiano; Rosaria Rinaldi. Physico-Chemical Properties of Inorganic NPs Influence the Absorption Rate of Aquatic Mosses Reducing Cytotoxicity on Intestinal Epithelial Barrier Model. Molecules 2021, 26, 2885 .

AMA Style

Valeria De Matteis, Makarena Rojas, MariaFrancesca Cascione, Stefano Mazzotta, Gian Di Sansebastiano, Rosaria Rinaldi. Physico-Chemical Properties of Inorganic NPs Influence the Absorption Rate of Aquatic Mosses Reducing Cytotoxicity on Intestinal Epithelial Barrier Model. Molecules. 2021; 26 (10):2885.

Chicago/Turabian Style

Valeria De Matteis; Makarena Rojas; MariaFrancesca Cascione; Stefano Mazzotta; Gian Di Sansebastiano; Rosaria Rinaldi. 2021. "Physico-Chemical Properties of Inorganic NPs Influence the Absorption Rate of Aquatic Mosses Reducing Cytotoxicity on Intestinal Epithelial Barrier Model." Molecules 26, no. 10: 2885.

Paper
Published: 19 April 2021 in Nanoscale
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Energy level scheme of multilayered quasi-2D BA3MA3Pb5Br16 films as a function of temperature.

ACS Style

Maria Luisa De Giorgi; Arianna Cretì; Maria-Grazia La-Placa; Pablo P. Boix; Henk J. Bolink; Mauro Lomascolo; Marco Anni. Amplified spontaneous emission in thin films of quasi-2D BA3MA3Pb5Br16 lead halide perovskites. Nanoscale 2021, 13, 8893 -8900.

AMA Style

Maria Luisa De Giorgi, Arianna Cretì, Maria-Grazia La-Placa, Pablo P. Boix, Henk J. Bolink, Mauro Lomascolo, Marco Anni. Amplified spontaneous emission in thin films of quasi-2D BA3MA3Pb5Br16 lead halide perovskites. Nanoscale. 2021; 13 (19):8893-8900.

Chicago/Turabian Style

Maria Luisa De Giorgi; Arianna Cretì; Maria-Grazia La-Placa; Pablo P. Boix; Henk J. Bolink; Mauro Lomascolo; Marco Anni. 2021. "Amplified spontaneous emission in thin films of quasi-2D BA3MA3Pb5Br16 lead halide perovskites." Nanoscale 13, no. 19: 8893-8900.

Review
Published: 29 January 2021 in Molecules
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Lead halide perovskites are currently widely investigated as active materials in photonic and optoelectronic devices. While the lack of long term stability actually limits their application to commercial devices, several experiments demonstrated that beyond the irreversible variation of the material properties due to degradation, several possibilities exist to reversibly modulate the perovskite characteristics by acting on the environmental conditions. These results clear the way to possible applications of lead halide perovskites to resistive and optical sensors. In this review we will describe the current state of the art of the comprehension of the environmental effects on the optical and electronic properties of lead halide perovskites, and of the exploitation of these results for the development of perovskite-based sensors.

ACS Style

Maria De Giorgi; Stefania Milanese; Argyro Klini; Marco Anni. Environment-Induced Reversible Modulation of Optical and Electronic Properties of Lead Halide Perovskites and Possible Applications to Sensor Development: A Review. Molecules 2021, 26, 705 .

AMA Style

Maria De Giorgi, Stefania Milanese, Argyro Klini, Marco Anni. Environment-Induced Reversible Modulation of Optical and Electronic Properties of Lead Halide Perovskites and Possible Applications to Sensor Development: A Review. Molecules. 2021; 26 (3):705.

Chicago/Turabian Style

Maria De Giorgi; Stefania Milanese; Argyro Klini; Marco Anni. 2021. "Environment-Induced Reversible Modulation of Optical and Electronic Properties of Lead Halide Perovskites and Possible Applications to Sensor Development: A Review." Molecules 26, no. 3: 705.

Journal article
Published: 01 October 2020 in Nanomedicine
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Stefano Leporatti; MariaFrancesca Cascione; Valeria De Matteis; Rosaria Rinaldi. Design of nano-clays for drug delivery and bio-imaging: can toxicity be an issue? Nanomedicine 2020, 15, 2429 -2432.

AMA Style

Stefano Leporatti, MariaFrancesca Cascione, Valeria De Matteis, Rosaria Rinaldi. Design of nano-clays for drug delivery and bio-imaging: can toxicity be an issue? Nanomedicine. 2020; 15 (25):2429-2432.

Chicago/Turabian Style

Stefano Leporatti; MariaFrancesca Cascione; Valeria De Matteis; Rosaria Rinaldi. 2020. "Design of nano-clays for drug delivery and bio-imaging: can toxicity be an issue?" Nanomedicine 15, no. 25: 2429-2432.

Journal article
Published: 25 September 2020 in Sensors
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In the last decades, the increase in global industrialization and the consequent technological progress have damaged the quality of the environment. As a consequence, the high levels of hazardous compounds such as metals and gases released in the atmosphere and water, have raised several concerns about the health of living organisms. Today, many analytical techniques are available with the aim to detect pollutant chemical species. However, a lot of them are not affordable due to the expensive instrumentations, time-consuming processes and high reagents volumes. Last but not least, their use is exclusive to trained operators. Contrarily, colorimetric sensing devices, including paper-based devices, are easy to use, providing results in a short time, without particular specializations to interpret the results. In addition, the colorimetric response is suitable for fast detection, especially in resource-limited environments or underdeveloped countries. Among different chemical species, transition and heavy metals such as iron Fe(II) and copper Cu(II) as well as volatile compounds, such as ammonia (NH3) and acetaldehyde (C2H4O) are widespread mainly in industrialized geographical areas. In this work, we developed a colorimetric paper-based analytical device (PAD) to detect different contaminants, including Fe2+ and Cu2+ ions in water, and NH3 and C2H4O in air at low concentrations. This study is a “proof of concept” of a new paper sensor in which the intensity of the colorimetric response is proportional to the concentration of a detected pollutant species. The sensor model could be further implemented in other technologies, such as drones, individual protection devices or wearable apparatus to monitor the exposure to toxic species in both indoor and outdoor environments.

ACS Style

Valeria De Matteis; MariaFrancesca Cascione; Gabriele Fella; Laura Mazzotta; Rosaria Rinaldi. Colorimetric Paper-Based Device for Hazardous Compounds Detection in Air and Water. A Proof of Concept. Sensors 2020, 20, 5502 .

AMA Style

Valeria De Matteis, MariaFrancesca Cascione, Gabriele Fella, Laura Mazzotta, Rosaria Rinaldi. Colorimetric Paper-Based Device for Hazardous Compounds Detection in Air and Water. A Proof of Concept. Sensors. 2020; 20 (19):5502.

Chicago/Turabian Style

Valeria De Matteis; MariaFrancesca Cascione; Gabriele Fella; Laura Mazzotta; Rosaria Rinaldi. 2020. "Colorimetric Paper-Based Device for Hazardous Compounds Detection in Air and Water. A Proof of Concept." Sensors 20, no. 19: 5502.

Journal article
Published: 30 June 2020 in Molecules
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Amplified Spontaneous Emission (ASE) threshold represents a crucial parameter often used to establish if a material is a good candidate for applications to lasers. Even if the ASE properties of conjugated polymers have been widely investigated, the specific literature is characterized by several methods to determine the ASE threshold, making comparison among the obtained values impossible. We quantitatively compare 9 different methods employed in literature to determine the ASE threshold, in order to find out the best candidate to determine the most accurate estimate of it. The experiment has been performed on thin films of an homopolymer, a copolymer and a host:guest polymer blend, namely poly(9,9-dioctylfluorene) (PFO), poly(9,9-dioctylfluorene-cobenzothiadiazole) (F8BT) and F8BT:poly(3- hexylthiophene) (F8BT:rrP3HT), applying the Variable Pump Intensity (VPI) and the Variable Stripe Length (VSL) methods. We demonstrate that, among all the spectral features affected by the presence of ASE, the most sensitive is the spectral linewidth and that the best way to estimate the ASE threshold is to determine the excitation density at the beginning of the line narrowing. We also show that the methods most frequently used in literature always overestimate the threshold up to more than one order of magnitude.

ACS Style

Stefania Milanese; Maria Luisa De Giorgi; Marco Anni. Determination of the Best Empiric Method to Quantify the Amplified Spontaneous Emission Threshold in Polymeric Active Waveguides. Molecules 2020, 25, 2992 .

AMA Style

Stefania Milanese, Maria Luisa De Giorgi, Marco Anni. Determination of the Best Empiric Method to Quantify the Amplified Spontaneous Emission Threshold in Polymeric Active Waveguides. Molecules. 2020; 25 (13):2992.

Chicago/Turabian Style

Stefania Milanese; Maria Luisa De Giorgi; Marco Anni. 2020. "Determination of the Best Empiric Method to Quantify the Amplified Spontaneous Emission Threshold in Polymeric Active Waveguides." Molecules 25, no. 13: 2992.

Review
Published: 31 May 2020 in Nanomaterials
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In the last years, there is a growing interest in the application of nanoscaled materials in cancer therapy because of their unique physico-chemical properties. However, the dark side of their usability is limited by their possible toxic behaviour and accumulation in living organisms. Starting from this assumption, the search for a green alternative to produce nanoparticles (NPs) or the discovery of green molecules, is a challenge in order to obtain safe materials. In particular, gold (Au NPs) and silver (Ag NPs) NPs are particularly suitable because of their unique physico-chemical properties, in particular plasmonic behaviour that makes them useful as active anticancer agents. These NPs can be obtained by green approaches, alternative to conventional chemical methods, owing to the use of phytochemicals, carbohydrates, and other biomolecules present in plants, fungi, and bacteria, reducing toxic effects. In addition, we analysed the use of green and stimuli-responsive polymeric bio-inspired nanovesicles, mainly used in drug delivery applications that have revolutionised the way of drugs supply. Finally, we reported the last examples on the use of metallic and Au NPs as self-propelling systems as new concept of nanorobot, which are able to respond and move towards specific physical or chemical stimuli in biological entities.

ACS Style

Valeria De Matteis; Loris Rizzello; MariaFrancesca Cascione; Eva Liatsi-Douvitsa; Azzurra Apriceno; Rosaria Rinaldi. Green Plasmonic Nanoparticles and Bio-Inspired Stimuli-Responsive Vesicles in Cancer Therapy Application. Nanomaterials 2020, 10, 1083 .

AMA Style

Valeria De Matteis, Loris Rizzello, MariaFrancesca Cascione, Eva Liatsi-Douvitsa, Azzurra Apriceno, Rosaria Rinaldi. Green Plasmonic Nanoparticles and Bio-Inspired Stimuli-Responsive Vesicles in Cancer Therapy Application. Nanomaterials. 2020; 10 (6):1083.

Chicago/Turabian Style

Valeria De Matteis; Loris Rizzello; MariaFrancesca Cascione; Eva Liatsi-Douvitsa; Azzurra Apriceno; Rosaria Rinaldi. 2020. "Green Plasmonic Nanoparticles and Bio-Inspired Stimuli-Responsive Vesicles in Cancer Therapy Application." Nanomaterials 10, no. 6: 1083.

Research article
Published: 24 April 2020 in The Journal of Physical Chemistry C
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Hybrid halide perovskites have achieved excellent efficiencies and remarkable performances, not just in photovoltaic cells, but also in light-emitting devices, like Light Emitting Diodes, Light Emitting Transistors, and Lasers. The lack of long-term stability is the main limit for the perovskite device commercial applications. While several works investigated the origin of the perovskite degradation for solar cell applications, the operational stability of perovskites under the optical pumping regime to have optical gain and lasing is largely unexplored. In this work, we investigate the origin of the photodegradation of the Amplified Spontaneous Emission (ASE) in MAPbBr3 thin films under nanosecond-UV laser irradiation as a function of the pump excitation density in different environments (air and vacuum). The correlation between the observed ASE operational stability and the irradiation-induced variations of the local morphology and the emission properties allowed us to demonstrate that the main process leading to ASE quenching is related to the film melting induced by localized heating. This also induces a bromine loss. Our results are relevant for the development of suitable strategies to improve the ASE and lasing operational stability of lead halide perovskite films.

ACS Style

Maria Luisa De Giorgi; Titti Lippolis; Nur Fadilah Jamaludin; Cesare Soci; Annalisa Bruno; Marco Anni. Origin of Amplified Spontaneous Emission Degradation in MAPbBr3 Thin Films under Nanosecond-UV Laser Irradiation. The Journal of Physical Chemistry C 2020, 124, 10696 -10704.

AMA Style

Maria Luisa De Giorgi, Titti Lippolis, Nur Fadilah Jamaludin, Cesare Soci, Annalisa Bruno, Marco Anni. Origin of Amplified Spontaneous Emission Degradation in MAPbBr3 Thin Films under Nanosecond-UV Laser Irradiation. The Journal of Physical Chemistry C. 2020; 124 (19):10696-10704.

Chicago/Turabian Style

Maria Luisa De Giorgi; Titti Lippolis; Nur Fadilah Jamaludin; Cesare Soci; Annalisa Bruno; Marco Anni. 2020. "Origin of Amplified Spontaneous Emission Degradation in MAPbBr3 Thin Films under Nanosecond-UV Laser Irradiation." The Journal of Physical Chemistry C 124, no. 19: 10696-10704.

Journal article
Published: 21 March 2020 in Applied Sciences
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In this work, we present a detailed optical investigation of the effects of the environment on the photoluminescence (PL) spectra and the relaxation dynamics of pristine and aged CsPbBr3 nanocrystal (NC) thin films. We demonstrate that, contrary to previous results on similar NCs, the PL intensity of pristine NCs is higher when the sample is in wet air than in vacuum, due to the passivation of defects reducing the free exciton trapping and the bound excitons non-radiative relaxation. The aged NCs show a PL intensity increase in wet air nine times stronger than the pristine ones, due to an interplay between static and dynamic effects, increasing the number of emitting NCs and reducing the non-radiative recombination rate of free excitons. These results improve the understanding of the possible interactions between perovskite NCs and the environment, which could be relevant for the development of optical gas sensors exploiting perovskite NCs.

ACS Style

Marco Anni; Arianna Cretì; Yuhai Zhang; Maria Luisa De Giorgi; Mauro Lomascolo. Investigation of the Role of the Environment on the Photoluminescence and the Exciton Relaxation of CsPbBr3 Nanocrystals Thin Films. Applied Sciences 2020, 10, 2148 .

AMA Style

Marco Anni, Arianna Cretì, Yuhai Zhang, Maria Luisa De Giorgi, Mauro Lomascolo. Investigation of the Role of the Environment on the Photoluminescence and the Exciton Relaxation of CsPbBr3 Nanocrystals Thin Films. Applied Sciences. 2020; 10 (6):2148.

Chicago/Turabian Style

Marco Anni; Arianna Cretì; Yuhai Zhang; Maria Luisa De Giorgi; Mauro Lomascolo. 2020. "Investigation of the Role of the Environment on the Photoluminescence and the Exciton Relaxation of CsPbBr3 Nanocrystals Thin Films." Applied Sciences 10, no. 6: 2148.

Journal article
Published: 24 December 2019 in Molecules
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The development of high performance optically pumped organic lasers operating in the deep blue still remains a big challenge. In this paper, we have investigated the photophysics and the optical gain characteristics of a novel fluorene oligomer functionalized by four triphenylamine (TPA) groups. By ultrafast spectroscopy we found a large gain spectral region from 420 to 500 nm with a maximum gain cross-section of 1.5 × 10-16 cm2 which makes this molecule a good candidate for photonic applications. Amplified Spontaneous Emission measurements (ASE) under 150 fs and 3 ns pump pulses have revealed a narrow emission at 450 nm with a threshold of 5.5 μJcm-2 and 21 μJcm-2 respectively. Our results evidence that this new fluorene molecule is an interesting material for photonic applications, indeed the inclusion of TPA as a lateral substituent leads to a high gain and consequently to a low threshold blue organic ASE.

ACS Style

Tersilla Virgili; Marco Anni; Maria Luisa De Giorgi; Rocio Borrego Varillas; Benedetta M. Squeo; Mariacecilia Pasini. Deep Blue Light Amplification from a Novel Triphenylamine Functionalized Fluorene Thin Film. Molecules 2019, 25, 79 .

AMA Style

Tersilla Virgili, Marco Anni, Maria Luisa De Giorgi, Rocio Borrego Varillas, Benedetta M. Squeo, Mariacecilia Pasini. Deep Blue Light Amplification from a Novel Triphenylamine Functionalized Fluorene Thin Film. Molecules. 2019; 25 (1):79.

Chicago/Turabian Style

Tersilla Virgili; Marco Anni; Maria Luisa De Giorgi; Rocio Borrego Varillas; Benedetta M. Squeo; Mariacecilia Pasini. 2019. "Deep Blue Light Amplification from a Novel Triphenylamine Functionalized Fluorene Thin Film." Molecules 25, no. 1: 79.

Research article
Published: 26 November 2019 in ACS Nano
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Semiconductor nanoplatelets (NPLs) have emerged as a very promising class of colloidal nanocrystals for light-emitting devices owing to their quantum-well-like electronic and optical characteristics. However, their lower photoluminescence quantum yield (PLQY) and limited stability have hampered the realization of their outstanding luminescent properties in device applications. Here, to address these deficiencies, we present a two-step synthetic approach that enables the synthesis of core/shell NPLs with precisely controlled shell composition for engineering their excitonic properties. The proposed CdSe colloidal quantum wells possess a graded shell, which is composed of a CdS buffer layer and a CdxZn1-xS gradient layer, and exhibit bright emission (PLQY 75-89%) in the red spectral region (634-648 nm) with a narrow emission linewidth (21 nm). These enhanced optical properties allowed us to attain low thresholds for amplified spontaneous emission (down to ~40 µJ/cm2) under nanosecond laser excitation. We also studied the electroluminescent performance of these NPLs by fabricating solution-processed light emitting devices (LEDs). In comparison to NPL-LEDs with CdSe/CdS core/shell NPLs, which exhibit an external quantum efficiency (EQE) value of only 1.80%, a significantly improved EQE value of 9.92% was obtained using graded-shell NPLs, the highest value for colloidal NPL-based-LEDs. In addition, the low efficiency roll-off characteristics of NPL-LEDs enabled a high brightness of up to ~46000 cd/m2 with an electroluminescence peak centered at 650 nm. These findings demonstrate the paramount role that heterostructure engineering occupies in enhancing the optoelectronic characteristics of semiconductor NPLs towards practically relevant levels.

ACS Style

Yusuf Kelestemur; Yevhen Shynkarenko; Marco Anni; Sergii Yakunin; Maria Luisa De Giorgi; Maksym V. Kovalenko. Colloidal CdSe Quantum Wells with Graded Shell Composition for Low-Threshold Amplified Spontaneous Emission and Highly Efficient Electroluminescence. ACS Nano 2019, 13, 13899 -13909.

AMA Style

Yusuf Kelestemur, Yevhen Shynkarenko, Marco Anni, Sergii Yakunin, Maria Luisa De Giorgi, Maksym V. Kovalenko. Colloidal CdSe Quantum Wells with Graded Shell Composition for Low-Threshold Amplified Spontaneous Emission and Highly Efficient Electroluminescence. ACS Nano. 2019; 13 (12):13899-13909.

Chicago/Turabian Style

Yusuf Kelestemur; Yevhen Shynkarenko; Marco Anni; Sergii Yakunin; Maria Luisa De Giorgi; Maksym V. Kovalenko. 2019. "Colloidal CdSe Quantum Wells with Graded Shell Composition for Low-Threshold Amplified Spontaneous Emission and Highly Efficient Electroluminescence." ACS Nano 13, no. 12: 13899-13909.

Journal article
Published: 30 October 2019 in Nanomaterials
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The green synthesis of nanoparticles (NPs) is currently under worldwide investigation as an eco-friendly alternative to traditional routes (NPs): the absence of toxic solvents and catalysts make it suitable in the design of promising nanomaterials for nanomedicine applications. In this work, we used the extracts collected from leaves of two cultivars (Leccino and Carolea) belonging to the species Olea Europaea, to synthesize silver NPs (AgNPs) in different pH conditions and low temperature. NPs underwent full morphological characterization with the aim to define a suitable protocol to obtain a monodispersed population of AgNPs. Afterwards, to validate the reproducibility of the mentioned synthetic procedure, we moved on to another Mediterranean plant, the Laurus Nobilis. Interestingly, the NPs obtained using the two olive cultivars produced NPs with different shape and size, strictly depending on the cultivar selected and pH. Furthermore, the potential ability to inhibit the growth of two woman cancer cells (breast adenocarcinoma cells, MCF-7 and human cervical epithelioid carcinoma, HeLa) were assessed for these AgNPs, as well as their capability to mitigate the bacteria concentration in samples of contaminated well water. Our results showed that toxicity was stronger when MCF-7 and Hela cells were exposed to AgNPs derived from Carolea obtained at pH 7 presenting irregular shape; on the other hand, greater antibacterial effect was revealed using AgNPs obtained at pH 8 (smaller and monodispersed) on well water, enriched with bacteria and coliforms.

ACS Style

Valeria De Matteis; Loris Rizzello; Chiara Ingrosso; Eva Liatsi-Douvitsa; Maria Luisa De Giorgi; Giovanni De Matteis; Rosaria Rinaldi. Cultivar-Dependent Anticancer and Antibacterial Properties of Silver Nanoparticles Synthesized Using Leaves of Different Olea Europaea Trees. Nanomaterials 2019, 9, 1544 .

AMA Style

Valeria De Matteis, Loris Rizzello, Chiara Ingrosso, Eva Liatsi-Douvitsa, Maria Luisa De Giorgi, Giovanni De Matteis, Rosaria Rinaldi. Cultivar-Dependent Anticancer and Antibacterial Properties of Silver Nanoparticles Synthesized Using Leaves of Different Olea Europaea Trees. Nanomaterials. 2019; 9 (11):1544.

Chicago/Turabian Style

Valeria De Matteis; Loris Rizzello; Chiara Ingrosso; Eva Liatsi-Douvitsa; Maria Luisa De Giorgi; Giovanni De Matteis; Rosaria Rinaldi. 2019. "Cultivar-Dependent Anticancer and Antibacterial Properties of Silver Nanoparticles Synthesized Using Leaves of Different Olea Europaea Trees." Nanomaterials 9, no. 11: 1544.

Review
Published: 29 October 2019 in Applied Sciences
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Lead halide perovskites are currently receiving increasing attention due to their potential to combine easy active layers fabrication, tunable electronic and optical properties with promising performance of optoelectronic and photonic device prototypes. In this paper, we review the main development steps and the current state of the art of the research on lead halide perovskites amplified spontaneous emission and on optically pumped lasers exploiting them as active materials.

ACS Style

Maria Luisa De Giorgi; Marco Anni. Amplified Spontaneous Emission and Lasing in Lead Halide Perovskites: State of the Art and Perspectives. Applied Sciences 2019, 9, 4591 .

AMA Style

Maria Luisa De Giorgi, Marco Anni. Amplified Spontaneous Emission and Lasing in Lead Halide Perovskites: State of the Art and Perspectives. Applied Sciences. 2019; 9 (21):4591.

Chicago/Turabian Style

Maria Luisa De Giorgi; Marco Anni. 2019. "Amplified Spontaneous Emission and Lasing in Lead Halide Perovskites: State of the Art and Perspectives." Applied Sciences 9, no. 21: 4591.

Journal article
Published: 21 September 2019 in International Journal of Molecular Sciences
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The widespread use of nanoparticles (NPs) in medical devices has opened a new scenario in the treatment and prevention of many diseases and infections owing to unique physico-chemical properties of NPs. In this way, silver nanoparticles (AgNPs) are known to have a strong antimicrobial activity, even at low concentrations, due to their ability to selectively destroy cellular membranes. In particular, in the field of dental medicine, the use of AgNPs in different kinds of dental prosthesis matrixes could be a fundamental tool in immunodepressed patients that suffer of different oral infections. Candida albicans (C. albicans), an opportunistic pathogenic yeast with high colonization ability, is one of the causative agents of oral cavity infection. In our work, we added monodispersed citrate-capping AgNPs with a size of 20 nm at two concentrations (3 wt% and 3.5 wt%) in poly(methyl methacrylate) (PMMA), the common resin used to develop dental prostheses. After AgNPs characterization, we evaluated the topographical modification of PMMA and PMMA with the addition of AgNPs by means of atomic force microscopy (AFM), showing the reduction of surface roughness. The C. albicans colonization on PMMA surfaces was assessed by the Miles and Misra technique as well as by scanning electron microscopy (SEM) at 24 h and 48 h with encouraging results on the reduction of yeast viability after AgNPs exposure.

ACS Style

Valeria De Matteis; MariaFrancesca Cascione; Chiara Cristina Toma; Giovanni Albanese; Maria Luisa De Giorgi; Massimo Corsalini; Rosaria Rinaldi. Silver Nanoparticles Addition in Poly(Methyl Methacrylate) Dental Matrix: Topographic and Antimycotic Studies. International Journal of Molecular Sciences 2019, 20, 4691 .

AMA Style

Valeria De Matteis, MariaFrancesca Cascione, Chiara Cristina Toma, Giovanni Albanese, Maria Luisa De Giorgi, Massimo Corsalini, Rosaria Rinaldi. Silver Nanoparticles Addition in Poly(Methyl Methacrylate) Dental Matrix: Topographic and Antimycotic Studies. International Journal of Molecular Sciences. 2019; 20 (19):4691.

Chicago/Turabian Style

Valeria De Matteis; MariaFrancesca Cascione; Chiara Cristina Toma; Giovanni Albanese; Maria Luisa De Giorgi; Massimo Corsalini; Rosaria Rinaldi. 2019. "Silver Nanoparticles Addition in Poly(Methyl Methacrylate) Dental Matrix: Topographic and Antimycotic Studies." International Journal of Molecular Sciences 20, no. 19: 4691.

Review
Published: 30 July 2019 in Biosensors
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: Microsystems and biomolecules integration as well multiplexing determinations are key aspects of sensing devices in the field of heavy metal contamination monitoring. The present review collects the most relevant information about optical biosensors development in the last decade. Focus is put on analytical characteristics and applications that are dependent on: (i) Signal transduction method (luminescence, colorimetry, evanescent wave (EW), surface-enhanced Raman spectroscopy (SERS), Förster resonance energy transfer (FRET), surface plasmon resonance (SPR)); (ii) biorecognition molecules employed (proteins, nucleic acids, aptamers, and enzymes). The biosensing systems applied (or applicable) to water and milk samples will be considered for a comparative analysis, with an emphasis on water as the primary source of possible contamination along the food chain.

ACS Style

Alessandra Aloisi; Antonio Della Torre; Angelantonio De Benedetto; Rosaria Rinaldi. Bio-Recognition in Spectroscopy-Based Biosensors for *Heavy Metals-Water and Waterborne Contamination Analysis. Biosensors 2019, 9, 96 .

AMA Style

Alessandra Aloisi, Antonio Della Torre, Angelantonio De Benedetto, Rosaria Rinaldi. Bio-Recognition in Spectroscopy-Based Biosensors for *Heavy Metals-Water and Waterborne Contamination Analysis. Biosensors. 2019; 9 (3):96.

Chicago/Turabian Style

Alessandra Aloisi; Antonio Della Torre; Angelantonio De Benedetto; Rosaria Rinaldi. 2019. "Bio-Recognition in Spectroscopy-Based Biosensors for *Heavy Metals-Water and Waterborne Contamination Analysis." Biosensors 9, no. 3: 96.

Journal article
Published: 23 July 2019 in International Journal of Molecular Sciences
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The side effects induced by nanoparticle exposure at a cellular level are one of the priority research topics due to the steady increase in the use of nanoparticles (NPs). Recently, the focus on cellular morphology and mechanical behavior is gaining relevance in order to fully understand the cytotoxic mechanisms. In this regard, we have evaluated the morphomechanical alteration in human breast adenocarcinoma cell line (MCF-7) exposed to TiO2NPs at two different concentrations (25 and 50 µg/mL) and two time points (24 and 48 h). By using confocal and atomic force microscopy, we demonstrated that TiO2NP exposure induces significant alterations in cellular membrane elasticity, due to actin proteins rearrangement in cytoskeleton, as calculated in correspondence to nuclear and cytoplasmic compartments. In this work, we have emphasized the alteration in mechanical properties of the cellular membrane, induced by nanoparticle exposure.

ACS Style

MariaFrancesca Cascione; Valeria De Matteis; Giacomo Mandriota; Stefano Leporatti; Rosaria Rinaldi. Acute Cytotoxic Effects on Morphology and Mechanical Behavior in MCF-7 Induced by TiO2NPs Exposure. International Journal of Molecular Sciences 2019, 20, 3594 .

AMA Style

MariaFrancesca Cascione, Valeria De Matteis, Giacomo Mandriota, Stefano Leporatti, Rosaria Rinaldi. Acute Cytotoxic Effects on Morphology and Mechanical Behavior in MCF-7 Induced by TiO2NPs Exposure. International Journal of Molecular Sciences. 2019; 20 (14):3594.

Chicago/Turabian Style

MariaFrancesca Cascione; Valeria De Matteis; Giacomo Mandriota; Stefano Leporatti; Rosaria Rinaldi. 2019. "Acute Cytotoxic Effects on Morphology and Mechanical Behavior in MCF-7 Induced by TiO2NPs Exposure." International Journal of Molecular Sciences 20, no. 14: 3594.

Journal article
Published: 28 May 2019 in Molecules
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Lauric acid is a green derivate that is abundant in some seeds such as coconut oil where it represents the most relevant fatty acid. Some studies have emphasized its anticancer effect due to apoptosis induction. In addition, the lauric acid is a Phase Change Material having a melting temperature of about 43.2 °C: this property makes it a powerful tool in cancer treatment by hyperthermal stress, generally induced at 43 °C. However, the direct use of lauric acid can have some controversial effects, and it can undergo degradation phenomena in the extracellular environment. For this reason, we have encapsulated lauric acid in a silica shell with a one-step and reproducible synthetic route in order to obtain a monodispersed [email protected] NPs with a good encapsulation efficiency. We have used these NPs to expose breast cancer cell lines (MCF-7) at different concentrations in combination with hyperthermal treatment. Uptake, viability, oxidative stress induction, caspases levels, and morphometric parameters were analyzed. These nanovectors showed double action in anticancer treatments thanks to the synergic effect of temperature and lauric acid activity.

ACS Style

Valeria De Matteis; MariaFrancesca Cascione; Maria Luisa De Giorgi; Stefano Leporatti; Rosaria Rinaldi. Encapsulation of Thermo-Sensitive Lauric Acid in Silica Shell: A Green Derivate for Chemo-Thermal Therapy in Breast Cancer Cell. Molecules 2019, 24, 2034 .

AMA Style

Valeria De Matteis, MariaFrancesca Cascione, Maria Luisa De Giorgi, Stefano Leporatti, Rosaria Rinaldi. Encapsulation of Thermo-Sensitive Lauric Acid in Silica Shell: A Green Derivate for Chemo-Thermal Therapy in Breast Cancer Cell. Molecules. 2019; 24 (11):2034.

Chicago/Turabian Style

Valeria De Matteis; MariaFrancesca Cascione; Maria Luisa De Giorgi; Stefano Leporatti; Rosaria Rinaldi. 2019. "Encapsulation of Thermo-Sensitive Lauric Acid in Silica Shell: A Green Derivate for Chemo-Thermal Therapy in Breast Cancer Cell." Molecules 24, no. 11: 2034.