Integrating infrared and visible-light images facilitates a more comprehensive understanding of scenes by amalgamating dual-sensor data derived from identical environments. Traditional CNN-based fusion techniques are predominantly confined to local feature emphasis due to their inherently limited receptive fields. Conversely, Transformer-based models tend to prioritize global information, which can lead to a deficiency in feature diversity and detail retention. Furthermore, methods reliant on single-scale feature extraction are inadequate for capturing extensive scene information. To address these limitations, this study presents GLMAFuse, an innovative dual-stream encoder–decoder network, which utilizes a multi-scale attention mechanism to harmoniously integrate global and local features. This framework is designed to maximize the extraction of multi-scale features from source images while effectively synthesizing local and global information across all layers. We introduce the global-aware and local embedding (GALE) module to adeptly capture and merge global structural attributes and localized details from infrared and visible imagery via a parallel dual-branch architecture. Additionally, the multi-scale attention fusion (MSAF) module is engineered to optimize attention weights at the channel level, facilitating an enhanced synergy between high-frequency edge details and global backgrounds. This promotes effective interaction and fusion of dual-modal features. Extensive evaluations using standard datasets demonstrate that GLMAFuse surpasses the existing leading methods in both qualitative and quantitative assessments, highlighting its superior capability in infrared and visible image fusion. On the TNO and MSRS datasets, our method achieves outstanding performance across multiple metrics, including EN (7.15, 6.75), SD (46.72, 47.55), SF (12.79, 12.56), MI (2.21, 3.22), SCD (1.75, 1.80), VIF (0.79, 1.08), Qbaf (0.58, 0.71), and SSIM (0.99, 1.00). These results underscore its exceptional proficiency in infrared and visible image fusion.