Delirium is a highly prevalent and costly neuropsychiatric condition that affects up to 87% of critically ill hospitalized patients. It impacts various cognitive domains, including attention, memory, perception, and motor functions, with symptoms such as behavioral changes, hallucinations, slurred speech, visual impairments, and fatigue. Non-pharmacological interventions have been shown to reduce the incidence and duration of delirium, with strategies like reality orientation, cognitive stimulation, family support, and physical support. However, the scalability of these interventions in hospital settings is limited by resource constraints, low patient engagement, and the complexity of delivery. Digital technology-based cognitive stimulation offers a potential solution to these barriers, though evidence supporting its effectiveness is currently insufficient. This narrative literature review explores both traditional and novel digital technology-based cognitive stimulation techniques for the prevention and management of delirium in acute hospital settings.

Delirium is the most common complication after major surgeries, with incidence rates ranging from 50% to 87%. Fortunately, postoperative delirium is preventable in up to 50% of patients, with the best preventive strategy being non-pharmacological interventions. However, these therapeutic approaches often face scalability challenges due to the complexity and high variability of their delivery, low patient engagement, and the existing clinical workforce constraints in the hospital setting. Cognitive stimulation is a non-pharmacological intervention with the potential to overcome the scalability and sustainability challenges of other non-pharmacological approaches, but evidence supporting its use is limited, especially in older adults at high risk for delirium. This narrative literature review examines evidence-based cognitive stimulation techniques being used as a non-pharmacological approach to prevent delirium in hospital settings.