Loay Eleyan

Dr. Loay Eleyan

orcid

Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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14 April 2021 in European Journal of Pediatrics
Verified
Journal Article
Closed access
PDF file
LELoay Eleyan
Loay Eleyan
AKAmeer Ahmed Khan
Ameer Ahmed Khan
GMGledisa Musollari
Gledisa Musollari
ACAshwini Suresh Chandiramani
Ashwini Suresh Chandiramani
SSSimran Shaikh
Simran Shaikh
AHAmer Harky
Amer Harky

9 January 2025 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
LELoay Eleyan
Loay Eleyan
AGAhmed Gonnah
Ahmed Gonnah
IFImran Farhad
Imran Farhad
ALAser Labib
Aser Labib
AVAlisha Chakera Varia
Alisha Chakera Varia
DAVID HESKETH ROBERTSDAVID HESKETH ROBERTS
DAVID HESKETH ROBERTS
Heart Failure (HF) is a prevalent condition which places a substantial burden on healthcare systems worldwide. Medical management implemented with exercise training (ET) plays a role in prognostic and functional capacity improvement. The aim of this review is to determine the effect of exercise training (ET) on HFpEF and HFrEF patients as well as exercise modality recommendations in frail and sarcopenic subpopulations. Pharmacological therapy structures the cornerstone of management in HF reduced ejection fraction (HFrEF) and aids improved survival rates. Mortality reduction with pharmacological treatments in HF preserved ejection fraction (HFpEF) are yet to be established. Cardiac rehabilitation (CR) and ET can play an important role in both HFrEF and HFpEF. Preliminary findings suggest that CR significantly improves functional capacity, exercise duration, and quality of life. ET has shown beneficial effects on peak oxygen consumption (pVO2) and 6 min walk test distance in HFrEF and HFpEF patients, as well as a reduction in hospitalisation and mortality rates; however, the limited scope of larger trials reporting on this underscores the need for further research. ET also has been shown to have beneficial effects on depression and anxiety levels. High-intensity training (HIT) and moderate continuous training (MCT) have both shown benefits, while resistance exercise training and ventilatory assistance may also be beneficial. ET adherence rates are higher when enrolled to a supervised programme, but prescription rates remain low worldwide. Larger robust trials are required to determine ET’s effects on HF, as well as the most efficacious and personalised exercise prescriptions in HF subtypes.

19 November 2024 in Preprints.org
Verified
Preprint
Open access
PDF file
LELoay Eleyan
Loay Eleyan
AGAhmed Gonnah
Ahmed Gonnah
IFImran Farhad
Imran Farhad
ALAser Labib
Aser Labib
AVAlisha Chakera Varia
Alisha Chakera Varia
DAVID HESKETH ROBERTSDAVID HESKETH ROBERTS
DAVID HESKETH ROBERTS
Heart Failure (HF) is a prevalent condition which places a substantial burden on healthcare systems worldwide. Pharmacological therapy structures the cornerstone of management in HF reduced ejection fraction (HFrEF), including angiotensin-converting enzyme inhibitors (ACE-I), angiotensin receptor-neprilysin inhibitors (ARNI), beta blockers (BB), mineralocorticoid receptor antagonists (MRA) and sodium/glucose co-transporter 2 (SGLT2) inhibitors, which all improve survival rates. Mortality reduction with pharmacological treatments in HF preserved ejection fraction (HFpEF) are yet to be established. Cardiac rehabilitation and exercise training can play an important role in both HFrEF and HFpEF. Cardiac rehabilitation significantly improves functional capacity, exercise duration and quality of life. Exercise training has shown beneficial effects on peak oxygen consumption (pVO2) and 6-minute walk test distance in HFrEF and HFpEF patients as well as a reduction in hospitalisation and mortality rates. ET also has been shown to have beneficial effects on depression and anxiety levels. High intensity training and moderate continuous training have both shown benefit, while resistance exercise training and ventilatory assistance may also be beneficial. ET adherence rates are higher when enrolled to a supervised programme but prescription rates remain low worldwide. Further research is required to establish the most efficacious exercise prescriptions in patients with HFrEF and HFpEF, but personalised exercise regimens should be considered as part of HF management.

6 December 2020 in Journal of Cardiac Surgery
Verified
Journal Article
Closed access
PDF file
AAAhmed Al‐Adhami
Ahmed Al‐Adhami
SISamsul Islam
Samsul Islam
VMVaibhav Mishra
Vaibhav Mishra
LELoay Eleyan
Loay Eleyan
TTThomas Theologou
Thomas Theologou