Background/Objectives: Chronic spontaneous urticaria (CSU) is an immune-mediated skin disorder, with increasing evidence suggesting its association with autoimmune thyroid diseases. The presence of antithyroid antibodies (anti-TPO and anti-TG) and autoimmune thyroid disease indicates shared immunological mechanisms in the pathogenesis of both conditions. This study examines the prevalence of autoimmune thyroid changes in patients with CSU. Methods: The study was conducted as a combined retrospective-prospective observational analysis. It included 43 patients with CSU and 50 healthy participants in the control group. Thyroid hormone levels (TSH, T3, T4), anti-TPO and anti-TG antibodies, as well as ultrasound characteristics of the thyroid gland, were analyzed. Results: In patients with CSU, a higher prevalence of hypothyroidism (27.9% vs. 4% in the control group), hypertension, asthma, and diabetes were observed. Elevated levels of anti-TPO antibodies were found in 51.2% of CSU patients, compared to only 6% in the control group (p < 0.001). Similarly, anti-TG antibodies were increased in 41.9% of CSU patients, compared to 4% in the control group. Additionally, ultrasound analysis revealed significant differences in thyroid morphology, with a heterogeneous structure observed in 72.1% of CSU patients, compared to only 14% in the control group (p < 0.001). Nodular changes were present in 34.88% of CSU patients, whereas the prevalence in the control group was only 6% (p < 0.001). Conclusions: Our results confirm a significant association between CSU and autoimmune thyroid diseases, including a high prevalence of anti-TPO and anti-TG antibodies, hypothyroidism, diffuse heterogeneity, and nodular changes. Additionally, elevated T3 hormone levels were common among CSU patients, while T4 levels did not differ significantly from those in the control group.

Background/Objectives: Adequate knowledge and correct attitudes about the HPV vaccine influence awareness of the importance of preventing HPV-related diseases, which is particularly important for future healthcare professionals. We aim to examine the share of correct answers and the prevalence of different attitudes about the HPV vaccine among active regular students of the Faculty of Medicine in Novi Sad. Methods: A cross-sectional study was conducted from 1 to 30 November 2023 using a structured survey questionnaire. Results: A total of 1760 students were included, of which 78% were female, with an average age of 21 years. Students who participated in prior HPV education) demonstrated significantly higher knowledge (81.92% vs. 65.60%, p < 0.001) and were more likely to recommend the vaccine to patients (89.91% vs. 82.99%, p < 0.001). Almost all vaccinated students (99.41%) would recommend the vaccine, compared to 82.91% of unvaccinated students (p < 0.001). Students who actively sought HPV information also showed a higher likelihood of recommending the vaccine (93.05% vs. 83.02%, p < 0.001). Moreover, those with sufficient self-assessed knowledge were more inclined to recommend the vaccine (89.88%) than those with insufficient knowledge (81.66%, p < 0.001). The analysis demonstrated that an increase in the number of correct answers in the knowledge evaluation corresponds to higher odds of recommending the HPV vaccine to patients (OR = 1.23, 95% CI 1.17–1.28). Positive attitudes prevailed, with 68.89% supporting more education on HPV vaccination. Conclusions: Students who previously attended education on HPV infection/vaccination and those who would recommend the vaccine have significantly higher levels of knowledge. The study highlights the importance of HPV-related education in shaping future healthcare professionals’ attitudes and knowledge.

It is estimated that more than 80% of people are infected with human papilloma virus (HPV) at some point in their lives. Knowledge about HPV infection and methods of its prevention is important for society as a whole. Medical students as future healthcare workers must be thoroughly informed about HPV infection in order to properly participate in the promotion of its prevention. The aim was to examine the knowledge and attitudes in relation to previous education about HPV infection and prevention methods. A cross-sectional study was conducted among undergraduate students at the Faculty of Medicine in Novi Sad (MFNS). The study covered all study programs and was conducted in the period from 1 to 30 November 2023, using a specially created survey questionnaire for the purposes of this research. 1760 surveys were collected, representing 70.4% of the total number of MFNS students. In the past year, only 26% of respondents attended some kind of education about HPV infection/vaccine. Statistical significance was observed in the difference between the responses of students who attended education in comparison to those who did not attend education in the past year (75.5% versus 63.3%, p < 0.001). Students who stated that they plan to get vaccinated in the following period answered the questions correctly in a higher percentage (87.5% versus 80.1%, p = 0.01). Students of the Faculty of Medicine in Novi Sad, as future healthcare workers, demonstrated certain knowledge and demonstrated right attitudes. Students who attended education about HPV infection and methods of prevention had more correct answers, as did students who plan to get vaccinated in the future.

Syphilitic panuveitis is a severe and diagnostically highly challenging manifestation of ocular syphilis. Its predominant posterior-segment involvement and its tendency to mimic noninfectious or viral uveitis may delay etiologic recognition and increase the risk of permanent vision loss. Rhegmatogenous retinal detachment (RRD) is a rare but vision-threatening complication that likely reflects advanced, inflammation-induced disruption of the vitreoretinal interface. A narrative literature review was conducted using the PubMed, Scopus, and Web of Science databases (January 2000 to 10 September 2025). Studies addressing the clinical presentation, imaging findings, pathophysiology, and management of syphilitic panuveitis and associated rhegmatogenous retinal detachment were analyzed. Infectious mimickers were also presented, with particular emphasis on West Nile virus (WNV). Evidence was synthesized qualitatively. Posterior uveitis and panuveitis are one of the most common ocular manifestations of syphilis. Posterior segment involvement in ocular syphilis is frequently bilateral, typically presenting with dense vitritis, retinal vasculitis, and optic neuropathy. RRD is a rare presenting complication, most often developing in areas of prior inflammatory retinitis and arising due to retinal necrosis, persistent vitreoretinal traction, and early proliferative vitreoretinopathy, which increases surgical complexity and may limit functional recovery. HIV coinfection often modifies disease severity. In relevant endemic or seasonal settings, WNV-associated ocular inflammation represents an important diagnostic pitfall. Syphilitic panuveitis should be considered early in patients presenting with unexplained posterior uveitis or panuveitis. Routine testing for syphilis and HIV in the uveitic laboratory palette, together with targeted evaluation for infectious mimickers, is essential to reduce diagnostic delay and avoid inappropriate immunosuppression. RRD should be recognized as a marker of advanced, inflammation-induced vitreoretinal interface damage requiring timely antimicrobial therapy and early involvement of vitreoretinal surgery.

Introduction: Peripheral retinal degenerations (PRD) encompass a broad spectrum of peripheral retinal alterations, ranging from benign atrophic changes to tractional lesions associated with retinal tears (RT) and rhegmatogenous retinal detachment (RRD). Despite increasing detection with modern peripheral imaging, the clinical relevance and management of many PRD remain controversial. This review aims to provide an imaging guided, risk based framework for PRD evaluation and management, emphasizing the role of posterior vitreous detachment (PVD), selective prophylactic intervention, and emerging AI-assisted risk stratification and decision support concepts. Methods: A narrative literature search was conducted in PubMed, Scopus, and Web of Science (January 2000 to September 2025) using predefined terms related to PRD, vitreoretinal traction, RT, RRD, PVD, ultra widefield (UWF) imaging, and peripheral OCT. Of 842 records identified, 29 studies met inclusion criteria and were qualitatively synthesized. Results: PRD can be functionally stratified into low risk atrophic lesions (paving stone degeneration, WWOP), intermediate entities (degenerative retinoschisis), and high risk tractional lesions (lattice degeneration, snail track degeneration, retinal tufts). PVD represents the key biomechanical event linking PRD with RT and RRD, particularly during acute symptomatic stages. UWF imaging and SS-OCT improve visualization of peripheral morphology and vitreoretinal interface abnormalities, enabling differentiation between benign lesions, tractionally unstable configurations, and subclinical RRD. Current evidence supports selective prophylactic laser photocoagulation in eyes with symptomatic RT, fellow eye RRD, or OCT confirmed tractional instability, while routine treatment of asymptomatic low risk PRD is not justified. AI-assisted decision support may help standardize risk interpretation by integrating multimodal imaging features with clinical risk modifiers within a human in the loop model. Conclusion: PRD management should be individualized using integrated clinical assessment and multimodal imaging, with intervention targeted to tractional instability and meaningful risk modifiers.

Syphilis remains a growing public health concern, with increasing reported incidence globally. Future healthcare professionals play a key role in preventio