Alejandro Caña-Pino

Dr. Alejandro Caña-Pino

orcid
Surgical Medical-Therapy Department, Medicine Faculty and He...

Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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Alejandro Caña-PinoAlejandro Caña-Pino
Alejandro Caña-Pino
Luis Espejo-AntúnezLuis Espejo-Antúnez
Luis Espejo-Antúnez
José Carmelo AdsuarJosé Carmelo Adsuar
José Carmelo Adsuar
MAMARIA DOLORES APOLO ARENAS
MARIA DOLORES APOLO ARENAS
Background: The joint position sense (JPS) has been used as an indirect marker of proprioception in subjects with non-specific chronic low back pain (NSCLBP), showing impairment in previous studies. It seems necessary to devise reliable tests to measure proprioceptive deficits in subjects with NSLBP. The objective of this study was to analyse the test–retest reliability and smallest real difference (SRD) of lumbar proprioception through the JPS indicator in a sample of patients with NSCLBP. Methods: Fifty participants with NSCLBP performed three repetitions of 30° lumbar flexion while standing and sitting using the iPhone® inclinometer application to measure the lumbar joint repositioning error. For the reliability analysis, we performed an intra-session test–retest. Results: The total sample ICC values were excellent for standing (0.96) and sitting (0.93) 30° lumbar flexion. In addition, our results showed that, for the total sample, an SRD < 12% can be considered as a true change in proprioception concerning this procedure. On the other hand, men have better reliability than women in both standing and sitting positions. Additionally, the sitting position has better reliability than the standing position. The standard error of measurement (SEM) percentage was 4.2 for standing and 3.8 for sitting. The SRD percentage was 11.6 for standing and 10.4 for sitting. Conclusions: The iPhone® inclinometer seems reliable for assessing proprioceptive ability through the lumbar joint repositioning error in subjects with NSCLBP in both standing (ICC = 0.96) and sitting (ICC = 0.93) positions. This technological device showed a lower measurement error for sitting position (SRD < 12%).

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MAMARIA DOLORES APOLO ARENAS
MARIA DOLORES APOLO ARENAS
AJAline Ferreira de Araújo Jerônimo
Aline Ferreira de Araújo Jerônimo
Alejandro Caña-PinoAlejandro Caña-Pino
Alejandro Caña-Pino
OFOrlando Jesus Fernandes
Orlando Jesus Fernandes
Joana AlegreteJoana Alegrete
Joana Alegrete
Jose ParracaJose Parraca
Jose Parraca
Cerebral palsy (CP) treatment includes physical therapy and various complementary therapies to the standard clinical treatment. However, there are not many reviews that focus on the methods used and evaluation procedures. This study aims to analyze which tools are most suitable for the evaluation and methodology of patients with CP treated with physical therapy. Following the PRISMA statement, through a PICOS strategy, PubMed/MEDLINE, Web of Science (WOS), Scopus, Science Direct, and Scielo were searched with the following terms: cerebral palsy AND (physical therapy modalities OR therapeutics) AND outcome assessment. The methodological quality of the RCTs was assessed with the Evidence Project risk of bias tool. Thirty-seven RCTs and six RCT protocols, comprising 1359 participants with different types of CP: spastic hemiplegia/paresis, spastic diplegia/paresis, and spastic CP, met the inclusion criteria, uncovering 21 variables measured through 77 different instruments and several interventions. The therapies most widely used in CP are gaming or technology-assisted therapies, aerobic training, hippotherapy, music therapy, gait training, and aquatic exercises. This study provides an overview of what the authors used in the neurorehabilitation field through procedure evaluation and checking the technological advance that began to be used.

27 April 2022 in Evidence-Based Complementary and Alternative Medicine
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ALAna Lavín-Pérez
Ana Lavín-Pérez
Daniel Collado-MateoDaniel Collado-Mateo
Daniel Collado-Mateo
Alejandro Caña-PinoAlejandro Caña-Pino
Alejandro Caña-Pino
Santos VillafainaSantos Villafaina
Santos Villafaina
Jose ParracaJose Parraca
Jose Parraca
MAMARIA DOLORES APOLO ARENAS
MARIA DOLORES APOLO ARENAS
This systematic review aimed to provide an up-to-date analysis of the effects of equine-assisted therapies (EAT) in people with multiple sclerosis (PwMS). The Preferred Reporting Items for Systematic Reviews and MetaAnalyses (PRISMA) guidelines were followed to conduct this systematic review. PubMed and Web of Science databases were employed in the search, which ended in February 2022. The risk of bias analysis was performed using the Evidence Project tool. After removing duplicates, thirty-nine studies were identified. However, only ten fulfilled the inclusion criteria and were included in this systematic review. Therefore, a total of 195 PwMS, aged between 40.3 and 51.3, were included in this systematic review. EAT-based interventions had a mean length of 13.6 weeks with a session´s frequency ranging from ten to once a week. All sessions involved real horses and lasted a mean of 34.4min. Among the included articles, four were randomized controlled trials (RCT), four did not perform randomization, and two employed a prepost design without a control group. RCTs showed positive effects on quality of life, fatigue, balance, spasticity, and gait speed. Furthermore, non-RCT showed improvements in balance, spasticity, and postural control (postural control was not assessed in RCT studies). Importantly, significant effects were only observed when the comparison group was inactive or followed usual care. Therefore, EAT is a promising and effective therapy to improve quality of life, fatigue, balance, spasticity, and gait speed in PwMS. However, since comparison groups are heterogeneous, results could vary depending on the research design. Moreover, the inclusion of noncontrolled studies (in order to have a wide perspective of the state of art) could increase the risk of bias and make the results be taken with caution.

11 September 2025 in Signals
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Alejandro Caña-PinoAlejandro Caña-Pino
Alejandro Caña-Pino
PHPaula Holgado-López
Paula Holgado-López
Stroke remains one of the leading causes of disability worldwide, often resulting in persistent impairments in gait and balance. Traditional rehabilitation methods—though beneficial—are limited by factors such as therapist dependency, low patient adherence, and restricted access. In recent years, sensor-supported technologies, including virtual reality (VR), robotic-assisted gait training (RAGT), and wearable feedback systems, have emerged as promising adjuncts to conventional therapy. This systematic review evaluates the effectiveness of wearable and immersive technologies for gait and balance rehabilitation in adult stroke survivors. Following PRISMA guidelines, a systematic search of the PubMed and ScienceDirect databases retrieved 697 articles. After screening, eight studies published between 2015 and 2025 were included, encompassing 186 participants. The interventions included VR-based gait training, electromechanical devices (e.g., HAL, RAGT), auditory rhythmic cueing, and smart insoles, compared against conventional rehabilitation or baseline function. Most studies reported significant improvements in motor function, dynamic balance, or gait speed, particularly when interventions were intensive, task-specific, and personalized. Patient engagement, adherence, and feasibility were generally high. However, heterogeneity in study design, small sample sizes, and limited long-term data reduced the strength of the evidence. Technologies were typically implemented as complementary tools rather than standalone treatments. In conclusion, wearable and immersive systems represent promising adjuncts to conventional stroke rehabilitation, with potential to enhance motor outcomes and patient engagement. However, the heterogeneity in protocols, small sample sizes, and methodological limitations underscore the need for more robust, large-scale trials to validate their clinical effectiveness and guide implementation.

15 September 2025 in Physiologia
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Alejandro Caña-PinoAlejandro Caña-Pino
Alejandro Caña-Pino
LPLucía Pesado-Fernández
Lucía Pesado-Fernández
Background: Falls are a leading cause of morbidity and loss of independence among older adults, and occupational therapy (OT) offers a unique, multidimensional approach to fall prevention. This systematic review evaluates the effectiveness of OT-based interventions for improving balance, mobility, functional performance, and psychological outcomes related to fall risk in older adults. Methods: This review followed PRISMA (2020) guidelines. A comprehensive search of PubMed, Scopus, Dialnet, and OTseeker was conducted from March to May 2025. The inclusion criteria targeted studies involving non-pharmacological, OT-led interventions in adults aged ≥65. Seventeen studies were selected, including randomized controlled trials, pilot studies, and quasi-experimental designs. The data extraction and quality appraisal were performed independently by two reviewers. Results: The included interventions varied among exercise-based programs (e.g., Tai Chi, Pilates), virtual reality training, home safety modifications, cognitive–behavioral therapy, and wearable technologies. Most of the studies reported significant improvements in postural balance, fear of falling, and functional independence. Environmental adaptations and educational strategies also yielded positive outcomes. However, a real-world fall incidence reduction was inconsistently reported, and the methodological heterogeneity limited the meta-analytic synthesis. Conclusions: Occupational therapy contributes significantly to fall prevention through multimodal, person-centered strategies that integrate physical, cognitive, and environmental components. Future research should aim to standardize the outcome measures, include high-risk populations, and assess the long-term efficacy and cost-effectiveness of OT-led programs.

1 January 2024 in International Journal of Vascular Medicine
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MAMARIA DOLORES APOLO ARENAS
MARIA DOLORES APOLO ARENAS
LGLaura Guerrero-Nogales
Laura Guerrero-Nogales
CMCésar Luis Díaz Muñoz
César Luis Díaz Muñoz
BCBerta Caro-Puértolas
Berta Caro-Puértolas
Jose ParracaJose Parraca
Jose Parraca
Alejandro Caña-PinoAlejandro Caña-Pino
Alejandro Caña-Pino
Diabetes mellitus (DM) is one of the most common chronic endocrine diseases, characterized by hyperglycemia, due to abnormal nitric oxide synthesis. The trend of an increase in the number of patients with DM continues. The medical and economic burden of DM is not only associated with hyperglycemia management but also with the management of DM‐related complications. Most chronic DM–associated complications are vascular in nature. Thus, hyperbaric oxygen therapy (HBOT) can be used for primary and/or secondary prevention of vascular complications. This systematic review is aimed at providing an up‐to‐date analysis of the effects of HBOT in patients with diabetic foot ulcers (DFUs) on the prevention of amputation, fitting, and rehabilitation of amputees. The Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines were followed to conduct this systematic review. PubMed and Web of Science (WOS) database were employed in the search, which ended in November 2023. A risk of bias analysis was performed using the Evidence Project tool. After analyzing the records obtained, 10 studies were identified. However, seven fulfilled the inclusion criteria and were included in this systematic review. All included patients were over 18 years of age and had DM. The degree of DFU was assessed with the Wagner scale, being between 2 and 4, and the age of previous treatment of these DFU was taken into account. The results of the current systematic review showed that significant improvements can be achieved with HBOT when comparing its effects to those of the control group that followed usual care. Most studies included in the review showed positive results for DFU, amputation prevention, fitting, and rehabilitation of amputees. Therefore, the use of a hyperbaric chamber and standard care, as opposed to standard care alone, is favorable in patients with chronic DFUs. Promising and positive results were achieved for wound healing in DFU and the prevention of amputations.