Patrick Couture

Dr. Patrick Couture

orcid

Research Focus & Metrics

Academic Career Length

34Years (1993-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 November 2016 in Canadian Journal of Cardiology
Verified
Journal Article
Closed access
TATodd J. Anderson
Todd J. Anderson
JGJean Grégoire
Jean Grégoire
GPGlen J. Pearson
Glen J. Pearson
ABArden R. Barry
Arden R. Barry
PCPatrick Couture
Patrick Couture
RWRichard Ward
Richard Ward

1 February 2013 in Canadian Journal of Cardiology
Verified
Journal Article
Closed access
TATodd J. Anderson
Todd J. Anderson
JGJean Grégoire
Jean Grégoire
RHRobert A. Hegele
Robert A. Hegele
PCPatrick Couture
Patrick Couture
GMG.B. John Mancini
G.B. John Mancini
EUEhud Ur
Ehud Ur

1 October 2009 in Canadian Journal of Cardiology
Verified
Journal Article
Closed access
JGJacques Genest
Jacques Genest
RMRuth McPherson
Ruth McPherson
JFJiri Frohlich
Jiri Frohlich
TATodd Anderson
Todd Anderson
NCNorm Campbell
Norm Campbell
EUEhud Ur
Ehud Ur

17 May 2017 in Nutrition Reviews
Verified
Journal Article
Open access
PDF file
PPPablo Pérez-Martínez
Pablo Pérez-Martínez
DMDimitri P. Mikhailidis
Dimitri P. Mikhailidis
VAVasilios G. Athyros
Vasilios G. Athyros
MBMonica Bullo
Monica Bullo
PCPatrick Couture
Patrick Couture
JLJosé López-Miranda
José López-Miranda
The importance of metabolic syndrome (MetS) lies in its associated risk of cardiovascular disease and type 2 diabetes, as well as other harmful conditions such as nonalcoholic fatty liver disease. In this report, the available scientific evidence on the associations between lifestyle changes and MetS and its components is reviewed to derive recommendations for MetS prevention and management. Weight loss through an energy-restricted diet together with increased energy expenditure through physical activity contribute to the prevention and treatment of MetS. A Mediterranean-type diet, with or without energy restriction, is an effective treatment component. This dietary pattern should be built upon an increased intake of unsaturated fat, primarily from olive oil, and emphasize the consumption of legumes, cereals (whole grains), fruits, vegetables, nuts, fish, and low-fat dairy products, as well as moderate consumption of alcohol. Other dietary patterns (Dietary Approaches to Stop Hypertension, new Nordic, and vegetarian diets) have also been proposed as alternatives for preventing MetS. Quitting smoking and reducing intake of sugar-sweetened beverages and meat and meat products are mandatory. Nevertheless, there are inconsistencies and gaps in the evidence, and additional research is needed to define the most appropriate therapies for MetS. In conclusion, a healthy lifestyle is critical to prevent or delay the onset of MetS in susceptible individuals and to prevent cardiovascular disease and type 2 diabetes in those with existing MetS. The recommendations provided in this article should help patients and clinicians understand and implement the most effective approaches for lifestyle change to prevent MetS and improve cardiometabolic health.

10 February 2006 in Journal of Internal Medicine
Verified
Journal Article
Open access
PDF file
PBP. J. Barter
P. J. Barter
CBC. M. Ballantyne
C. M. Ballantyne
RCR. Carmena
R. Carmena
MCM. Castro Cabezas
M. Castro Cabezas
MCM. John Chapman
M. John Chapman
KWK. M. S. Williams
K. M. S. Williams
: There is abundant evidence that the risk of atherosclerotic vascular disease is directly related to plasma cholesterol levels. Accordingly, all of the national and transnational screening and therapeutic guidelines are based on total or LDL cholesterol. This presumes that cholesterol is the most important lipoprotein‐related proatherogenic risk variable. On the contrary, risk appears to be more directly related to the number of circulating atherogenic particles that contact and enter the arterial wall than to the measured concentration of cholesterol in these lipoprotein fractions. Each of the atherogenic lipoprotein particles contains a single molecule of apolipoprotein (apo) B and therefore the concentration of apo B provides a direct measure of the number of circulating atherogenic lipoproteins. Evidence from fundamental, epidemiological and clinical trial studies indicates that apo B is superior to any of the cholesterol indices to recognize those at increased risk of vascular disease and to judge the adequacy of lipid‐lowering therapy. On the basis of this evidence, we believe that apo B should be included in all guidelines as an indicator of cardiovascular risk. In addition, the present target adopted by the Canadian guideline groups of an apo B <90 mg dL−1 in high‐risk patients should be reassessed in the light of the new clinical trial results and a new ultra‐low target of <80 mg dL−1 be considered. The evidence also indicates that the apo B/apo A‐I ratio is superior to any of the conventional cholesterol ratios in patients without symptomatic vascular disease or diabetes to evaluate the lipoprotein‐related risk of vascular disease.

1 November 2016 in Advances in Nutrition
Verified
Journal Article
Open access
PDF file
JDJean-Philippe Drouin-Chartier
Jean-Philippe Drouin-Chartier
DBDidier Brassard
Didier Brassard
MTMaude Tessier-Grenier
Maude Tessier-Grenier
JCJulie Anne Côté
Julie Anne Côté
MLMarie-Eve Labonté
Marie-Eve Labonté
BLBenoît Lamarche
Benoît Lamarche
The objective of this systematic review was to determine if dairy product consumption is detrimental, neutral, or beneficial to cardiovascular health