Stephen M. Spindel

Dr. Stephen M. Spindel

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Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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31 December 2024 in Surgeries
Verified
Journal Article
Open access
PDF file
ADAlbert Dweck
Albert Dweck
BFBrandon Edward Ferrell
Brandon Edward Ferrell
DGDaniel Guttman
Daniel Guttman
SSStephen M. Spindel
Stephen M. Spindel
Tadahisa SugiuraTadahisa Sugiura
Tadahisa Sugiura
Aortic stenosis (AS) is the most common valve disease in developed countries, with severe cases traditionally managed through surgical aortic valve replacement (SAVR). More recently, transcatheter aortic valve replacement (TAVR) has been used as a less invasive alternative, especially for patients deemed high-risk for surgery. This review aims to compare SAVR and TAVR by examining the efficacy, patient selection criteria, complications, and evolving guidelines. SAVR is the preferred option for patients at low surgical risk or with anatomical challenges unsuitable for TAVR. It offers well-documented durability and favorable long-term survival. Conversely, TAVR has gained acceptance for intermediate- and high-risk patients, with shorter recovery times and reduced immediate postoperative risks. However, questions surrounding its long-term durability in younger populations persist. Complications differ between the approaches, with TAVR associated with vascular access injuries and arrhythmic events, while SAVR presents risks tied to open surgery. As clinical guidelines evolve, patient age, comorbidities, and life expectancy play critical roles in determining the optimal intervention. This review highlights the need for tailored treatment approaches, given the expanding indications and evolving evidence for both SAVR and TAVR in AS management.

6 July 2020 in Journal of Cardiac Surgery
Verified
Journal Article
Closed access
PDF file
JMJavier Mejia
Javier Mejia
SSStephen M. Spindel
Stephen M. Spindel
APAmit Pawale
Amit Pawale
SIShinobu Itagaki
Shinobu Itagaki
PBPercy Boateng
Percy Boateng

21 January 2024 in JTCVS Techniques
Verified
Journal Article
Open access
SSStephen M. Spindel
Stephen M. Spindel
RDReginald E. Du
Reginald E. Du
KJKatrina J. Jiang
Katrina J. Jiang
JSJasmine Su
Jasmine Su

1 March 2024 in JTCVS Techniques
Verified
Journal Article
Open access
SSStephen M. Spindel
Stephen M. Spindel
CZChristopher M. Zumwalt
Christopher M. Zumwalt
JSJasmine Su
Jasmine Su
ASAutumn P. Stevenson
Autumn P. Stevenson

11 October 2023 in JTCVS Techniques
Verified
Journal Article
Open access
SSStephen M. Spindel
Stephen M. Spindel
RDReginald E. Du
Reginald E. Du
JSJasmine Su
Jasmine Su
APAntonio Polanco
Antonio Polanco
KJKatrina J. Jiang
Katrina J. Jiang
ASAutumn P. Stevenson
Autumn P. Stevenson

2 September 2024 in Multimedia Manual of Cardio-Thoracic Surgery
Verified
Journal Article
Closed access
SSStephen M. Spindel
Stephen M. Spindel
MGManuel Giraldo-Grueso
Manuel Giraldo-Grueso
The definitive management of combined aortic arch and descending aortic pathologies such as aneurysms and dissections is either a single or staged operation associated with high morbidity and mortality. Stroke, kidney dysfunction, coagulopathy and high blood transfusion requirements are all affiliated with hypothermic circulatory arrest and prolonged cardiopulmonary bypass times. Considering the perilous nature of these operations, the authors describe a step-by-step zone 2 arch replacement as a staged frozen elephant trunk procedure, which provides an adequate landing zone for a later-placed endovascular stent yet maintains a short cardiopulmonary bypass time and no circulatory arrest.