In this paper, a four-channel optical emission module is developed using hybrid integration technology that integrates directly modulated laser (DML) chips, low-noise amplifier (LNA) chips, and control circuits, with dimensions of 24.4 mm × 21 mm × 5.9 mm. This module enables high-gain signal output and minimizes crosstalk between neighboring channels while improving integration. An equivalent circuit model of radio frequency (RF) signal transmission is established, and the accuracy of the model and the effectiveness of the approach to improve signal gain are verified using simulations and experiments. With optimized thermal management, the module has the ability to operate at stable temperatures across an ambient range of −55 °C to 75 °C. The module has a channel wavelength spacing of approximately 1 nm, and the −3 dB bandwidth of each channel exceeds 20 GHz. The crosstalk between neighboring channels is less than −65 dB. In the range of 0.8~25 GHz, the four-channel gain is approximately 15 dB through the integration of the LNA chip. The module achieves a noise figure (NF) of less than 30 dB.