Further chemical investigation of the fruits of the mangrove, Avicennia marina, afforded three new phenylethyl glycosides, marinoids J–L (1–3), and a new cinnamoyl glycoside, marinoid M (4). The structures of isolates were elucidated on the basis of extensive spectroscopic analysis and by comparison of the data with those of related secondary metabolites. The antioxidant activity of the isolates was evaluated using the cellular antioxidant assay (CAA), and compounds 1–4 showed antioxidant activities, with EC50 values ranging from 23.0 ± 0.71 μM to 247.8 ± 2.47 μM.
The phylogenetic studies of the tribe Alsineae (Caryophyllaceae) have revealed a clearer boundary between the genus Stellaria and related genera, primarily relying on the morphological characteristics of style 3, stamens 10 and petals deeply bifid. However, the newly-published species in China, which have 5 styles or ten or more lobes per petal, challenge this boundary and necessitate further studies. In this paper, we reviewed six newly-published Chinese species of Stellaria, utilising both molecular phylogenetic evidence from nuclear ribosomal internal transcribed spacer (ITS) and four plastid regions (trnL-F, matK, rbcL, rps16) and morphological evidence. Our results demonstrated that the five new species (Stellaria abaensis, S. multipartita, S. pentastyla, S. procumbens and S. zhuxiensis) were nested within the genus Stellaria, but Stellaria motuoensis was sister to the genus Schizotechium. Herein, we accepted four new Stellaria species and proposed a new combination in Schizotechium and a new synonym in Stellaria. Additionally, we described a new species Stellaria longipedicellata from Sichuan Province, China, which was distinguished from the closely-related species Stellaria decumbens by its glabrous body, linear-lanceolate leaves, long pedicellate flowers, prostrate growth habit and flowers nearly equal to or slightly shorter than sepals. Both molecular and morphological evidence support the treatment of S. longipedicellata as a new species of the genus Stellaria.
Stellaria pentastyla sp. nov. (Caryophyllaceae) is described and illustrated as a new species from Yunnan Province of China on the basis of both morphological and molecular data [nuclear ITS and two plastid regions (matK and trnL-F)]. The new species is similar to S. palustris and S. graminea from which differs by the number styles (5 vs. 3), the shorter leaves (10–13 mm vs. 20–45 mm and 5–50 mm, respectively). S. pentastyla is also similar to S. patens from which can be distinguished in having 5 styles (vs. 3 styles) and glabrous stem (vs. pubescent), and to S. lanipes from which differs from by styles (5 vs. 3), glabrous nodes (vs. densely white lanate on the nodes), and sessile leaves (vs. proximal leaves with very short petiolate).
Callicarpa stoloniformis sp. nov. (Lamiaceae) is described as a new species from Fujian Province of China on the basis of both morphological and molecular data. The new species is morphologically most close to C. hainanensis. However, it can be distinguished from the latter by its unique procumbent life form, adventitious roots at nodes, papery leaves, cup‐shaped or campanulate calyx, truncate or shallow fissure calyx lobes, and smaller fruits. In addition, the new species is also similar with C. basitruncata, a species only known from the original description and the photograph of holotype, but it can differ from the latter by its procumbent shrub, purple terete branchlets with apparent linear lenticels, adventitious roots at nodes, and papery larger leaves with prominently cordate leaf base. Original photographs, illustration, distribution map, and a comparative morphological table, as well as an identification key of the related taxa are provided.
Two new compounds, carneusins A-B (1-2), as well as fifteen known compounds (3-17), were isolated from the marine-derived fungus Aspergillus carneus GXIMD00519. Their structures were elucidated by the analysis of detailed spectroscopic data and quantum chemistry calculations. All the compounds were evaluated for their antibacterial, antibiofilm and cytotoxic effects. Compound 1 showed a moderate inhibitory effect against MRSA with the MIC value of 32 µg/mL. Compound 2 exhibited an anti-microfouling effect against biofouling bacterial Vibrio rotiferianus and Alteromonas macleodii with MIC value of 64 µg/mL. Compound 5 displayed antibiofilm activity against A. macleodii with the EC50 value of 10.42 ± 0.58 µg/mL. Compounds 1, 3, 4, 8 and 15 showed cytotoxicity against human pancreatic cancer cell lines SW1990, colorectal adenocarcinoma cell line DLD1, human pancreatic cancer cell line PANC1, and human hepatocellular carcinoma cell line Bel7402 with IC50 values ranging of 2.75-17.77 µM.