Background: Breast cancer (BC) is the most common malignancy affecting women globally, significantly impacting their quality of life (QoL). This study aimed to assess the prevalence and severity of symptoms in newly diagnosed BC patients undergoing chemotherapy in Oman using the Edmonton Symptom Assessment System (ESAS-A); Materials and Methods: A cross-sectional study was conducted between December 2022 and February 2024 at the Sultan Qaboos Comprehensive Cancer Care and Research Centre (SQCCCRC), University Medical City, Oman. The study included 105 Omani women, aged 18 to 60, diagnosed with stage I to III BC and undergoing chemotherapy. Symptom evaluation was performed using ESAS-A. Descriptive statistics were employed to summarize socio-demographic characteristics and clinical outcomes, while the Mann–Whitney U test and multiple linear regression analysis were used to examine associations between independent variables and symptom scores; Results: Out of 127 invited participants, 105 (82.6%) agreed to participate. The average age was 43.6 years (SD = 7.2). Fatigue (37.1%), poor well-being (30.5%), and drowsiness (27.6%) were the most commonly reported symptoms. Anxiety and depression affected 21.9% and 17.1% of participants, respectively. Linear regression analysis showed that having children was linked to higher fatigue and shortness of breath, while inversely associated with pain. A family history of chronic disease was significantly correlated with higher depression scores; Conclusions: This study is the first in Oman to utilize ESAS-A for assessing symptom burden in newly diagnosed BC patients undergoing chemotherapy. The findings highlight the importance of personalized symptom management and enhanced supportive care to improve patient well-being.

Purpose Mothers diagnosed with breast cancer in collectivist, faith-oriented societies face dilemmas regarding the timing, manner, and extent of disclosure of their illness to their children and extended family members. However, evidence addressing this issue within Arab contexts remains limited. This phenomenological qualitative study explored how Omani mothers with breast cancer navigate disclosure, interpret familial and communal responses, and employ coping strategies within sociocultural and religious frameworks. Methods In-depth semistructured interviews were conducted in Arabic with 18 Omani mothers diagnosed with stage I–III breast cancer, parenting at least one child aged 6–18 years. Participants were recruited from a national cancer care center in Muscat. The interviews were audio-recorded, transcribed verbatim, translated into English, and analyzed using the framework method, supported by NVivo. Results Three themes emerged: (1) illness disclosure and communication strategies; (2) family and community responses to the diagnosis; and (3) coping strategies grounded in faith, patience, and behavioral adjustment. Women’s experiences were shaped by maternal roles, anticipated stigma, and faith-informed interpretations of illness. Disclosure decisions influenced the mobilization of support within kinship networks. Furthermore, coping mechanisms integrated religious meaning-making with efforts to maintain normalcy. Conclusion These findings underscore the need for culturally responsive, family-centered psychosocial care in cancer services.