The characterization of territory in Peru’s Andean regions faces significant challenges due to a lack of comprehensive methodologies capable of addressing the complexity of these contexts. This research aims to bridge that gap by developing a methodology that integrates the CFS-RAI Principles with the Working with People (WWP) model to provide a detailed, contextualized framework for territorial analysis. The framework leverages the CFS-RAI Principles’ focus on sustainable agriculture and the WWP model’s proven effectiveness in fostering social transformation in Aymara communities in southern Peru. The research centers on Paucar del Sara Sara, a province in Ayacucho, Peru, characterized by a Human Development Index (HDI) of 0.42 and significant development potential rooted in opportunities for organic agriculture and collaboration with the mining sector. Employing geographic analysis and qualitative methods, this study draws comparisons with existing literature and presents insights from the case study to develop a matrix of key variables for territorial analysis in Andean regions. Additionally, the research introduces a methodology for defining mining companies’ areas of influence while addressing prevalent socioeconomic challenges in these territories.