Shun-Yi Wang

Dr. Shun-Yi Wang

orcid

Research Focus & Metrics

Academic Career Length

20Years (2007-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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8 June 2018 in Nature Communications
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Journal Article
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YFYi Fang
Yi Fang
TRTorben Rogge
Torben Rogge
LALutz Ackermann
Lutz Ackermann
SWShun-Yi Wang
Shun-Yi Wang
SJShunjun Ji
Shunjun Ji
Chalcogen-containing compounds have received considerable attention because of their manifold applications in agrochemicals, pharmaceuticals, and material science. While many classical methods have been developed for preparing organic sulfides, most of them exploited the transition-metal-catalyzed cross-couplings of aryl halides or pseudo halides with thiols or disulfides, with harsh reaction conditions usually being required. Herein, we present a user-friendly, nickel-catalyzed reductive thiolation of unactivated primary and secondary alkyl bromides with thiosulfonates as reliable thiolation reagents, which are easily prepared and bench-stable. Furthermore, a series of selenides is also prepared in a similar fashion with selenosulfonates as selenolation reagents. This catalytic method offers a facile synthesis of a wide range of unsymmetrical alkyl-aryl or alkyl-alkyl sulfides and selenides under mild conditions with an excellent tolerance of functional groups. Likewise, the use of sensitive and stoichiometric organometallic reagents can be avoided.

24 February 2014 in Chemical Communications
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JCJia-Jia Cao
Jia-Jia Cao
TZTong-Hao Zhu
Tong-Hao Zhu
SWShun-Yi Wang
Shun-Yi Wang
ZGZheng-Yang Gu
Zheng-Yang Gu
XWXiang Wang
Xiang Wang
SJShunjun Ji
Shunjun Ji
An efficient method for the construction of 6-alkyl phenanthridines by tert-butyl peroxybenzoate (TBPB)-mediated 2-isocyanobiaryl insertion with 1,4-dioxane was established. Two new C–C bonds were formed in this reaction via a sequential C(sp3)–H/C(sp2)–H bond functionalization under metal-free conditions.

11 March 2016 in Chemical Science
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Journal Article
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ZGZheng-Yang Gu
Zheng-Yang Gu
JCJia-Jia Cao
Jia-Jia Cao
SWShun-Yi Wang
Shun-Yi Wang
SJShunjun Ji
Shunjun Ji
An efficient and practical synthesis of benzothiazine by K2S initiated sulfur insertion reaction with enaminones via electron catalysis is developed.

3 May 2017 in ACS Catalysis
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Journal Article
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ZGZheng-Yang Gu
Zheng-Yang Gu
YLYuan Liu
Yuan Liu
FWFei Wang
Fei Wang
XBXiaoguang Bao
Xiaoguang Bao
SWShun-Yi Wang
Shun-Yi Wang
SJShunjun Ji
Shunjun Ji

11 May 2022 in Nature Communications
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Journal Article
Open access
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FWFei Wang
Fei Wang
YCYing Chen
Ying Chen
CZChunyu Zhang
Chunyu Zhang
LALutz Ackermann
Lutz Ackermann
SWShun-Yi Wang
Shun-Yi Wang
Disulfides are widely found in natural products and find a wide range of applications in life sciences, materials chemistry and other fields. The preparation of disulfides mainly rely on oxidative couplings of two sulfur containing compounds. This strategy has many side reactions and other shortcomings. Herein, we describe the reductive nickel-catalyzed cross-electrophile coupling of unactivated alkyl bromides with symmetrical alkyl- and aryltetrasulfides to form alkyl-alkyl and aryl-alkyl unsymmetrical disulfides. This approach for disulfide synthesis is practical, relies on easily available, unfunctionalized substrates, and is scalable. We investigated the mechanism of this transformation and found that the tetrasulfide compound does not selectively break the central S–S bond, but regio-selectively generates trisulfide intermediates.

1 August 2017 in Organic Letters
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Journal Article
Closed access
PXPei Xu
Pei Xu
FWFei Wang
Fei Wang
TWTian-Qi Wei
Tian-Qi Wei
LYLing Yin
Ling Yin
SWShun-Yi Wang
Shun-Yi Wang
SJShunjun Ji
Shunjun Ji