Urban Flooding is one of the most prevalent natural hazards worldwide, leading to substantial human and economic losses. Therefore, the assessment and mapping of flood hazard levels are essential for reducing the impact of future flood disasters. This study develops and integrates a methodology to evaluate urban flood susceptibility in Nangarhar Province, Afghanistan, a semi-arid region with limited prior research. Landsat imagery from 2004 to 2024 was used to analyze land use land cover change (LULCC), indicating that built-up areas increased from 124 to 180 km² in 2004 to 2024, respectively, while agricultural land decreased from 1978 km² to 1883 km² during the same period. Climate data exhibit increases in temperatures and intensifying rainfall, exacerbating flood hazards. Geospatial analysis of elevation, slope, drainage density, and proximity to water bodies highlights the high susceptibility of low-lying areas. The Analytical Hierarchy Process (AHP) was employed to integrate diverse flood risk factors and produce accurate flood hazard maps. The findings show that very-high flood susceptibility zones expanded from 1537 to 1699 km² in 2004 to 2024, whereas low-susceptibility zones declined from 131 km² to 110 km². Socioeconomic indicators such as population density, built-up density, and education accessibility were also incorporated into the assessment. This study underscores the need for adaptive land use planning, resilient drainage systems, and community-based flood risk reduction strategies. The findings provide actionable insights for sustainable flood management and demonstrate the value of combining GIS, remote sensing, and multi-criteria analysis in data-scarce, conflict-affected regions.