Objective: The aim of the study was to assess the short-term effects of direct intramuscular (i.m.) corticosteroid therapy on fetal biophysical profile, baseline fetal heart rate and the nonstress test, which indicate the degree of fetal hypoxia. Method: We evaluated the effect of direct i.m. fetal single-dose dexamethasone (4 mg/kg) on the fetal biophysical profile 2 h before and 2–4 h after corticosteroid therapy in 41 fetuses in the 32nd week of gestation at risk of preterm delivery. Risk factors for preterm delivery included pregnancy-induced hypertension and preeclampsia. Result: There was a statistically significant difference between fetal breathing movements before and after corticosteroid therapy (p = 0.019; 95% confidence interval for difference –11.75, –1.12). No significant changes were observed between baseline fetal heart rate before and after corticosteroid therapy (p = 0.99; 95% confidence interval for difference –4.81, +4.81), biophysical profile before and after fetal corticosteroid therapy, p = 0.235 as well as the nonstress test before and after therapy (p = 0.564). Conclusion: Direct corticosteroid i.m. fetal therapy results in increasing profound short-term fetal breathing movements. There are no changes in baseline fetal heart rate, biophysical profile score, and nonstress test.
12 February 2013 in Clinical and Experimental Hypertension
Purpose: An aim was to determine the degree and the mode of variation of PI of middle cerebral artery in no risk pregnancies and in pregnancies with gestational hypertension, after the constant sound stimuli. Method: Study included 343 patients divided in two groups. Group 1: low risk pregnancies and group 2: gestational hypertension. Ultrasound prenatal auditory screening was performed after the 27th week of gestation. Results: The percentage of fetuses with increase of cerebral blood flow was slightly higher in the pregnancies with hypertension. Conclusion: An average change of PI of median cerebral artery was higher in this group.
Introduction/Objective. Breech presentation occurs in 3?4% singleton pregnancies at term and its management is still a controversial in obstetric practice. The aim of this study was to determine the factors that indicate breech delivery management and to compare maternal and neonatal outcomes in vaginal breech delivery, planned Cesarean section (C-section) and emergency C-section at the Hospital for Gynecology and Obstetrics of the Zemun Clinical Hospital Centre. Methods. This was a retrospective study conducted from 2015 to 2019. Depending on the mode of delivery, patients were divided in three group. In this study, we have analyzed maternal risk factors and postpartum complications, delivery details and neonatal characteristics and outcomes. Results. The study included 176 women with singleton fetus in breech presentation. The incidence of breech deliveries was 2.12%. Most common way of delivery was vaginal with 47.72%. In all three groups, the majority of women were primiparous, at term, mostly without chronical and gestational diseases. Vaginal delivery was stimulated with oxytocin in 91.67%, and as a help for delivery various maneuvers were used. Maternal mortality and short-term complications during hospitalization period were reported in none of the groups. No significant difference in newborns birth weight between the groups was observed. The highest rate of birth injuries was in newborns from emergency C-section ? 10%. Conclusion. The results of our study have shown that vaginal delivery could be a very safe option for both mother and newborn.