Dr. Jiajie Zhang

Jiajie Zhang is a professor at the School of Pharmaceutical Science, Southern Medical University. Author's education background: 2001–2004, First Military Medical University, pharmacology, Ph.D; 1993–1996, South China Normal University, macromolecular chemistry and physics, Master; 1986–1990, Hunan Normal University, chemistry, Bachelor. Author's work experience: 2009–2023, Southern Medical University, School of Pharmaceutical Science, research fellow; 2004–2009, Southern Medical University, School of Pharmaceutical Science, associate research fellow; 1997–2004, First Military Medical University, Institute of Pharmacology, research assistant. The author's current and previous research interests include design and the synthesized and structure–activity relationship of kinase inhibitors for anti-cancer research. (1) Haikui Yang# , Ruohong Yan# , Ying Jiang , Zichao Yang , Xingmei Zhang , Mingfeng Zhou , Xiaoyun Wu , Tingting Zhang*, Jiajie Zhang*， Design, synthesis and biological evaluation of 2-amino-4-(1,2,4-triazol)pyridine derivatives as potent EGFR inhibitors to overcome TKI-resistance, Eur J Med Chem, 2020,187:111966. (2) Siming Liu# , Ying Jiang# , Ruohong Yan , Zhonghuang Li , Shanhe Wan, Tingting Zhang , Xiaoyun Wu , Ju Hou , Zhengguang Zhu, Yuanxin Tian*, Jiajie Zhang*, Design, synthesis and biological evaluations of 2-amino-4-(1-piperidine) pyridine derivatives as novel anti crizotinib-resistant ALK/ROS1 dual inhibitors, Eur J Med Chem, 2019,179:358-375