(1) Background: The interaction between the human body and the Earth’s magnetic field at Schumann resonances (SRs) is one of the important fundamental questions of science that continues to be studied. The aim of this study was to create a working theoretical foundation for the interaction of the human body with SRs. (2) Methods: Extensive research was carried out in the literature with the aim of comprehensively presenting data on SRs and creating a working concept of their interaction with the human body. (3) Results: General data on SRs, a theoretical basis for justifying their interaction with the human body, possible mechanisms of influence and research results on the functioning of human internal organs were presented. (4) An interaction of the human body with SRs exists and has been scientifically proven. This interaction has been studied most significantly between SRs and the human nervous system. SRs affect functional indicators of the cardiovascular system: heart rate and blood pressure. Studying the influence of SRs on the course and pathogenesis of non-communicable diseases is a promising direction. Low-frequency SRs decrease the risk of developing acute myocardial infarction, and there is a tendency for them to promote cases of chronic kidney disease. SRs are an important external natural factor influencing the human body.
Background/Objectives: This review has been prepared to promote interest in the interdisciplinary study of mitochondrial dysfunction (MD) and atherosclerosis. This review aims to describe the state of this problem and indicate the direction for further implementation of this knowledge in clinical medicine. Methods: Extensive research of the literature was implemented to elucidate the role of the molecular mechanisms of MD in the pathogenesis of atherosclerosis. Results: A view on the pathogenesis of atherosclerosis through the prism of knowledge about MD is presented. MD is the cause and primary mechanism of the onset and progression of atherosclerosis. It is proposed that this problem be considered in the context of a continuum. Conclusions: MD and atherosclerosis are united by common molecular mechanisms of pathogenesis. Knowledge of MD should be used to argue for a healthy lifestyle as the primary way to prevent atherosclerosis. The development of new approaches to diagnosing and treating MD in atherosclerosis is an urgent task and challenge for modern science.
21 November 2022 in Ukraïnsʹkij žurnal medicini, bìologìï ta sportu
The purpose of the study was to conceptualize a system of views on the role of internal electromagnetic fields in the human body to understand the essence of the course of metabolism, the phenomena of biological life and health. Materials and methods. General scientific methods (dismemberment and integration of elements of the studied system, imaginary experiment, logical, historical research, analysis, induction, deduction, and synthesis of knowledge) and theoretical methods (method of constructing theory, logical methods, and rules of normative nature) were used in this theoretical study. Results and discussion. The informative and analytical presentation of the magneto-electrochemical theory of metabolism, life and health is published in the article in the form of the main postulates and conclusions of the atomic and molecular levels of the structure of living biological systems, including humans. This is the first attempt by scientists to combine existing fundamental knowledge about the role of electromagnetic processes in the human body from the standpoint of Systemic Medicine. 12 postulates and 4 conclusions regarding the atomic level and 26 postulates and 6 conclusions regarding the molecular level of the structure of living biological systems, including humans, are presented. All materials are available for viewing in the monograph “Magneto-electrochemical theory of metabolism. Conceptualization”. Conclusion. The life of a biological system is a process of magneto-electric activation of its biomolecules, which starts and ensures their biochemical activity and determines structural integrity in their collective interaction of a single organism. Modern deepening of fundamental knowledge to the level of the course of magneto-electric processes at the molecular level in living biological systems is expedient to be fully integrated into medical science with a change of the electrochemical paradigm of metabolism to a magneto-electrochemical one. Knowledge and understanding of the quantum-mechanical features of the functioning of biopolymers in living systems, the understanding of the essence of their energy functioning, the organization of the form and role of electromagnetic components is the next step to deepening the fundamental knowledge of the pathogenesis of diseases of internal organs with a further approach to optimizing their treatment and prevention
Background/Objectives: Noncommunicable diseases (NCDs) are a very important medical problem. The key role of mitochondrial dysfunction (MD) in the occurrence and progression of NCDs has been proven. However, the etiology and pathogenesis of MD itself in many NCDs has not yet been clarified, which makes it one of the most serious medical problems in the modern world, according to many scientists. Methods: An extensive research in the literature was implemented in order to elucidate the role of MD and NCDs’ risk factors in the pathogenesis of NCDs. Results: The authors propose to take a broader look at the problem of the pathogenesis of NCDs. It is important to understand exactly how NCD risk factors lead to MD. The review is structured in such a way as to answer this question. Based on a systematic analysis of scientific data, a theoretical concept of modern views on the occurrence of MD under the influence of risk factors for the occurrence of NCDs is presented. This was done in order to update MD issues in clinical medicine. MD and NCDs progress throughout a patient’s life. Based on this, the review raised the question of the existence of an NCDs continuum. Conclusions: MD is a universal mechanism that causes organ dysfunction and comorbidity of NCDs. Prevention of MD involves diagnosing and eliminating the factors that cause it. Mitochondria are an important therapeutic target.