Jack Womble

Mr. Jack Womble


Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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21 February 2025 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
SPShannon Parness
Shannon Parness
JWJack Womble
Jack Womble
THTori Hester
Tori Hester
Panagiotis TasoudisPanagiotis Tasoudis
Panagiotis Tasoudis
AMAurelie Merlo
Aurelie Merlo
Aortic valve disease (AVD) is a highly prevalent condition worldwide. Aortic valve replacement (AVR) is the surgical treatment for those with severe disease. Common etiologies of AVD include aortic stenosis (AS), aortic insufficiency (AI), endocarditis, and congenital diseases. Shared decision-making plays a large role in the treatment methodology chosen for each patient. Selection of valve type and surgical intervention requires strong considerations of age and compatibility with vitamin K antagonists (VKAs) to ensure optimal post-operative outcomes. Due to the development of novel surgical techniques, including transcatheter AVR (TAVR) and placement of sutureless valves, patients who previously had limited access to AVD surgical options can now be considered for AVR. Further research into therapeutic development is imperative to improve patient short- and long-term outcomes as well as widen surgical candidacy for those seeking AVR for the management of AVD. Overall, AVR will continue to hold its prominent role in the treatment of AVD.

19 December 2024 in Preprints.org
Verified
Preprint
Open access
PDF file
SPShannon Parness
Shannon Parness
JWJack Womble
Jack Womble
THTori Hester
Tori Hester
Panagiotis TasoudisPanagiotis Tasoudis
Panagiotis Tasoudis
AMAurelie Merlo
Aurelie Merlo
Aortic valve disease (AVD) is a highly prevalent condition worldwide. Aortic valve replacement (AVR) is the surgical treatment for those with severe disease. Common etiologies of AVD include aortic stenosis (AS), aortic insufficiency (AI), endocarditis, and congenital diseases. Shared decision making plays a large role in the treatment methodology chosen for each patient. Selection of valve type and surgical intervention require strong considerations to age and compatibility with vitamin K antagonists (VKAs) to ensure optimal post-operative outcomes. Due to the development of novel surgical techniques, including transcatheter AVR (TAVR) and placement of sutureless valves, patients who previously had limited access to AVD surgical options can now be considered for AVR. Further research into therapeutic development is imperative to improve patient short- and long-term outcomes as well as widening surgical candidacy for those seeking AVR for management of AVD. Overall, AVR will continue to hold its prominent role in the treatment of AVD.