Dermatological diseases pose a significant challenge due to their chronic nature, complex pathophysiology, and the need for effective, patient-friendly treatments. Recent advancements in liposomal and gel-based formulations have played a crucial role in improving drug delivery, therapeutic efficacy, and patient compliance. Liposomal formulations have garnered considerable attention in dermatology due to their ability to encapsulate both hydrophilic and lipophilic compounds, enabling controlled drug release and enhanced skin penetration. However, challenges such as formulation complexity, stability issues, and regulatory constraints remain. Similarly, gel-based formulations are widely used due to their ease of application, biocompatibility, and ability to retain active ingredients. However, they also face limitations, including restricted penetration depth, susceptibility to microbial contamination, and challenges in achieving sustained drug release. The integration of liposomal and gel-based technologies offers a promising strategy to overcome current challenges and optimize dermatological drug delivery. This review explores both well-established therapies and recent innovations, offering a comprehensive overview of their applications in the treatment of prevalent dermatological conditions. Ultimately, continued research is essential to refine these formulations, expanding their clinical utility and enhancing therapeutic effectiveness in dermatology.
In recent decades, there has been significant worldwide interest in the emergence of a new invasive species known as Achatina fulica. This is due to its dangerous habits for the environment, its biological characteristics and the fact that it is the intermediate host of several nematode parasites, such as Angiostrongylus cantonensis. This land snail species is native to tropical African countries, but has been introduced, accidentally or deliberately, to other parts of the world to be used for different purposes and is now established in a large part of the tropics. Since the 1980s, hundreds of researchers have been interested in the beneficial properties of its mucus, ranging from the antimicrobial and anticancer properties to the use of its powdered shell as a biocatalyst. This literature review aims to objectively describe the positive and negative aspects associated with the spread of A. fulica, highlighting in particular the opportunities for the local populations deriving from a conscious exploitation of this mollusc.