Dr. Antonella Tomassetti has extensive experience and background in biochemistry, cellular and molecular biology, applied to the field of oncology. She also acquired her expertise during several placements in European and US laboratories. At present, she is a Staff Scientist at Fondazione IRCCS Istituto Nazionale dei Tumori (INT). The research focus of Dr. Tomassetti is to understand the molecular mechanisms leading to the initiation and metastatic spread of ovarian cancer; to generate suitable pre-clinical models for testing therapies that target specific biochemical pathways; and to identify and functionally characterize recognizable histological or molecular markers that could be used for early cancer detection and as therapeutic targets. She was the first to demonstrate the positive role of E-cadh in modulating EGFR/PI3K and activation iand growth of ovarian cancer cells. She is an independent group leader in the Unit of Molecular Therapies at the Italian Cancer Institute of Milan, Italy.
Research Keywords & Expertise
Cell Adhesion
Molecular Markers
Signal Transduction
3D tissue culture
Epithelial ovarian can...
Fingerprints
25%
Epithelial ovarian cancer.
11%
Cell Adhesion
Short Biography
Dr. Antonella Tomassetti has extensive experience and background in biochemistry, cellular and molecular biology, applied to the field of oncology. She also acquired her expertise during several placements in European and US laboratories. At present, she is a Staff Scientist at Fondazione IRCCS Istituto Nazionale dei Tumori (INT). The research focus of Dr. Tomassetti is to understand the molecular mechanisms leading to the initiation and metastatic spread of ovarian cancer; to generate suitable pre-clinical models for testing therapies that target specific biochemical pathways; and to identify and functionally characterize recognizable histological or molecular markers that could be used for early cancer detection and as therapeutic targets. She was the first to demonstrate the positive role of E-cadh in modulating EGFR/PI3K and activation iand growth of ovarian cancer cells. She is an independent group leader in the Unit of Molecular Therapies at the Italian Cancer Institute of Milan, Italy.