In many fields, data-driven decision making has become essential due to machine learning (ML), which provides insights that improve productivity and quality of life. A basic machine learning approach called clustering helps find comparable data points. Clustering plays a critical role in the identification of patient subgroups and the customisation of treatment in the context of tuberculosis (TB) research. While prior studies have recognized its utility, a comprehensive comparative analysis of multiple clustering methods applied to TB data is lacking. Using TB data, this study thoroughly assesses and contrasts four well-known machine learning clustering algorithms: spectral clustering, DBSCAN, hierarchical clustering, and k-means. To evaluate the quality of a cluster, quantitative measures such as the silhouette score, Davies–Bouldin index, and Calinski–Harabasz index are utilised. The results provide quantitative insights that enhance comprehension of clustering and guide future research.

Colorectal cancer is the third most prevalent type of cancer globally, and it typically progresses unnoticed, making early detection via effective screening methods crucial. This study presents the TASPP-UNet, an advanced deep learning model that integrates Atrous Spatial Pyramid Pooling (ASPP) blocks and a ResNet-50 encoder to enhance polyp boundary delineation accuracy in colonoscopy images. We utilized augmented datasets from Kvasir-SEG and CVC Clinic-DB, which included up to 2000 images, to enrich the training examples’ variability. The TASPP-UNet achieved a superior IOU of 0.9276, compared to 0.9128 by the ResNet50-UNet and 0.8607 by the standard U-Net, demonstrating its efficacy in precise segmentation tasks. Notably, this model exhibited impressive computational efficiency with a processing speed of 151.1 frames per second (FPS), underscoring its potential for real-time clinical applications aimed at early and accurate colorectal cancer detection. This performance highlights the model’s capability not only to improve diagnostic accuracy but also to enhance clinical workflows, potentially leading to better patient outcomes.