General-purpose computers have become ubiquitous and important for everyday life, but they are difficult for people with paralysis to use. Specialized software and personalized input devices can improve access, but often provide only limited functionality. In this study, three research participants with tetraplegia who had multielectrode arrays implanted in motor cortex as part of the BrainGate2 clinical trial used an intracortical brain-computer interface (iBCI) to control an unmodified commercial tablet computer. Neural activity was decoded in real time as a point-and-click wireless Bluetooth mouse, allowing participants to use common and recreational applications (web browsing, email, chatting, playing music on a piano application, sending text messages, etc.). Two of the participants also used the iBCI to “chat” with each other in real time. This study demonstrates, for the first time, high-performance iBCI control of an unmodified, commercially available, general-purpose mobile computing device by people with tetraplegia.
Mobility is a cornerstone of health and quality of life, particularly in older adults. Digital mobility outcomes (DMOs) from real-world walking data offer crucial insights into the functional status and early markers of mobility decline. This study provides reference values for walking activity, pace, rhythm, and gait bout-to-bout variability in community-dwelling older adults and evaluates the effects of age, sex, height, and weight on these parameters. Using data from 200 older adults (aged 65–94 years) from the InCHIANTI Study and applying the Mobilise-D computational pipeline, we analyzed real-world walking over a week. Significant differences by sex and age were found, with males showing higher walking activity in younger age groups (65–74 and 75–84 years) but not in the oldest group (85–94 years). Additionally, we observed non-linear trends in mobility metrics with age, indicating an accelerated reduction in mobility at certain age ranges. These findings underscore the importance of monitoring real-world walking data to pinpoint critical periods of mobility decline and guide targeted interventions. This work offers valuable benchmarks for clinical assessments and future research.
Con las transformaciones generadas por la globalización —el mundo posmoderno, la era tecnológica, la incertidumbre, el caos—, las organizaciones han originado cambios transcendentales desde su visión paradigmática, como eje medular para afrontar las distintas realidades contextuales. Desde esta visión, el aprender a aprender en las organizaciones representa un bastión importante y estrategia de mejora continua en su talento humano, que debe instaurarse en toda la estructura organizativa de la empresa. Por lo tanto, el presente artículo de revisión tiene como objetivo general analizar la nueva concepción de las organizaciones basado en el aprender a aprender. Urgen cambios fundamentales en las organizaciones desde su talento humano, comprendiendo que los procesos de aprendizaje se logran desde las distintas experiencias vividas.
El presente estudio tiene como objetivo identificar el impacto generado por los medios de información en las mujeres migrantes venezolanas residentes en Lima, Perú, en el contexto del COVID-19, y saber cómo se relaciona con el estado emocional de ellas, así como con el cumplimiento de las recomendaciones sanitarias. Este estudio correlacional retrospectivo recolectó información de 385 de estas mujeres migrantes a través de una encuesta virtual realizada durante las primeras semanas (19 de marzo-30 de abril de 2020) de las medidas de aislamiento social obligatorio tomadas por el gobierno del Perú. Los principales resultados muestran que existe una asociación entre los efectos de los medios y el impacto emocional; ninguno de los medios de comunicación analizados brindó información tranquilizadora, sino inquietante. Este estudio concluye que los medios de comunicación agudizaron los sentimientos de preocupación, miedo, temor y enojo de las mujeres venezolanas migrantes.
20 October 2023 in IEEE Transactions on Biomedical Engineering
Objective: Postural control naturally declines with age, leading to an increased risk of falling. Within clinical settings, the deployment of balance assessments has become commonplace, facilitating the identification of postural instability and targeted interventions to forestall falls among older adults. Some studies have ventured beyond the controlled laboratory, leaving, however, a gap in our understanding of balance in real-world scenarios. Methods: Previously reported algorithms were used to build a finite-state machine (FSM) with four states: walking, turning, sitting, and standing. The FSM was validated against video annotations (gold standard) in an independent dataset with data collected on 20 older adults. Later, the FSM was applied to data from 168 community-dwelling older people in the InCHIANTI cohort who were evaluated both in the laboratory and then remotely in real-world conditions for a week. A 70/30 data split with recursive feature selection and resampling techniques was used to train and test four machine-learning models. Results: In identifying fallers, duration, distance, and mean frequency computed during standing in real-world settings revealed significant relationships with fall risk. Also, the best-performing model (Lasso Regression) built on real-world balance features had a higher area under the curve (AUC, 0.76) than one built on lab-based assessments (0.57). Conclusion: Real-world balance features differ considerably from laboratory balance assessments (Romberg test) and have a higher predictive capacity for identifying patients at high risk of falling. Significance: These findings highlight the need to move beyond traditional laboratory-based balance measures and develop more sensitive and accurate methods for predicting falls.
Recibido: 17 de febrero del 2019Aprobado: 29 de abril del 2019El presente artículo de revisión plantea al fenómeno educativo como eje fundamental de formación ciudadana y cambios sociales dentro de procesos democráticos, teniendo como eje de acción medular al ser desde el ser. Por lo tanto, tiene como objetivo general comprender la educación desde los fundamentos del equilibrio del poder para el desarrollo de la ciudadanía y democracia. Desde la metodología se asumió un tipo de investigación documental bajo un diseño bibliográfico, utilizándose la técnica de análisis de contenido para comprender la realidad de estudio desde la educación como proceso de cambios en el ser biopsicosocial-espiritual y ecológico. Se concluye que las nociones de poder, educación, ciudadanía y democracia, constituyen ejes medulares de formación en el ser, reflejándose en cada accionar de su vida cotidiana.