Background Indocyanine green fluorescence angiography (ICG-FA) in colorectal surgery allows changing the section line (CSL) based on objective evaluation of the vascular supply. The aim of this prospective study is to report our experience with CSL based on ICG-FA during colorectal surgery and to report risk factors influencing it. Methods From 2014 to 2023, all patients who underwent any colorectal surgical procedure with anastomosis and ICG-FA were enrolled. Patients for whom changing the section line based on ICG-FA was not necessary were included in group A, and patients for whom ICG-FA determined a CSL were included in group B. Results Four hundred consecutive patients underwent laparoscopic surgery, except for two. In 334 patients (group A, 83.5%), CSL based on ICG-FA did not occur, while CSL occurred in 66 patients (group B, 16.5%). In group B, median time from ICG injection and fluorescence visualization (TIFV) was statistically significantly longer than in group A (28.5 s versus 23 s, p = 0.003). Anastomotic leakage rate was 1.8% and 4.5% in group A and B, respectively, without a statistically significant difference. The multivariate logistic regression analysis identified age > 60 years and TIFV ≥ 20 s as independent risk factors for CSL. Conclusions Factors influencing the CSL are identified, which could be useful to determine the cases in which this technology should be mandatory and to consider when ICG is not available. These factors could also influence the decision-making process during surgery, such as using protective ileostomy.

Background: Endoscopic retrograde cholangiopancreatography (ERCP) is the preferred technique for treating pathologies of the bile duct. It has been suggested that this procedure, combined with sphincterotomy, may influence the subsequent development of long-term complications. The main objective of this study was to determine the long-term complications of biliopancreatic disease after ERCP and their potential association with the development of biliopancreatic neoplasms. Methods: This retrospective cohort study included 576 patients who underwent ERCP (referred to as index ERCP) with sphincterotomy for benign biliary disease, with a minimum follow-up period of more than 2 years. Results: The incidence of long-term benign and neoplastic pathologies after ERCP was analyzed. The most common findings were recurrence of choledocholithiasis in 70 patients (12.1%), cholangitis “sine materia” in 27 patients (4.7%), and acute pancreatitis in 8 patients (1.4%). Eight patients (1.4%) developed hepatobiliopancreatic neoplasms, including 4 cases of pancreatic neoplasms (0.7%), 1 cholangiocarcinoma (0.2%), 1 ampulloma (0.2%), and 2 intrahepatic neoplasms (0.3%). Multivariate analysis revealed that factors such as age over 50 years, previous biliary surgery, diversion of the bile duct (BD) to the digestive tract, dilation of the BD, stent placement, biopsy, and cholecystectomy were factors associated with an increased risk of long-term benign complications. Conclusion: Endoscopic retrograde cholangiopancreatography with sphincterotomy is associated with an increased long-term risk of subsequent benign biliopancreatic disease. However, our data do not allow us to establish a direct relationship with the development of biliopancreatic neoplasms. Cite this article as: Ibáñez M, López C, Trujillo J, Ramón Gómez J, Vaquero Puerta C, Carlos Martin del Olmo J. Long-term risks of benign and malign complications after endoscopic sphincterotomy in the management of benign biliopancreatic pathology: A cohort study. Eurasian J Med., 2024;56(1):1-6

Purpose: Acute appendicitis (AA) is the most frequent surgical entity in the emergency department, but its correct diagnosis remains challenging. To improve diagnosis, clinical prediction rules (CPRs) have been created to establish objective scores for the probability of suffering AA. In this study, we establish scores indicating whether laparoscopy would be superior to clinical observation or repeat diagnostic test. Methods: A retrospective observational study was conducted with 433 patients submitted to surgery for suspected AA using a laparoscopic approach. The Alvarado, Raja Isteri Pengiran Anak Saleha Appendicitis, appendicitis inflammatory response, and adult appendicitis score scales were applied in each case to establish a high, medium, or low probability of suffering AA. Results: Of the 433 patients analyzed, 381 (88.0%) had AA. Twelve (2.8%) were converted to open surgery, and complications were observed in 54 (12.5%) cases. The CPRs studied showed statistically significant differences between AA and negative appendectomies. However, in patients with intermediate probability scores, the diagnostic accuracy of the CPRs evaluated was not adequate. Conclusions: Laparoscopic surgery can serve as a diagnostic tool for patients with intermediate AA probability scores because of its low associated morbidity and mortality and because it affords a direct diagnosis of the problem, allowing determination of the appropriate treatment.

Objectives: To analyze the factors associated with recurrent choledocholithiasis following endoscopic retrograde cholangiopancreatography (ERCP) with biliary sphincterotomy (BS). Methods: A retrospective, observational, and analytical cohort study was conducted. Patients who underwent ERCP with BS for benign biliary pathology and were followed for a minimum of two years were included. Demographic and clinical data were collected, including the indication for the procedure, endoscopic findings, performance and timing of cholecystectomy (before or after ERCP), and the need for repeat procedures. Episodes of choledocholithiasis were defined as those occurring at least six months after the initial ERCP. Follow-up continued until patient death, loss of follow-up, or the conclusion of the study. Results: A total of 576 patients were included, with a mean age of 71 years and an average follow-up duration of 131 months. Sixty-nine cases of recurrent choledocholithiasis were documented (11.96%). Multivariate analysis identified the following predictive factors for recurrence: age over 50 years, bile duct dilation upon initial evaluation, history of biliary surgery, cytology sampling, placement of biliary stents, repeated ERCP, biliary diversion procedures, and cholecystectomy prior to the index ERCP. Conclusions: Biliary duct dilation, advanced age, and any previous manipulation of the biliary tree are associated with an increased risk of recurrent choledocholithiasis. Cholecystectomy performed after the initial ERCP was not associated with a reduced recurrence risk.

Background/Objectives: Gastric cancer is a major global health concern and a leading cause of cancer-related death. While surgical resection remains the cornerstone of curative treatment, postoperative morbidity and mortality are significant issues. This study aimed to identify factors associated with postoperative morbidity and mortality in patients undergoing laparoscopic gastrectomy for gastric adenocarcinoma. Results: The median age was 73 years. Eighteen total gastrectomies (15%) and eighty-eight subtotal gastrectomies (66.6%) were performed. Major complications (Clavien-Dindo ≥ III) occurred in 22.3% of patients, and the hospital mortality rate was 7.5%. Independent predictors of morbidity included anemia (OR 2.49, p = 0.047), extended lymphadenectomy (OR 5.09, p = 0.002), and conversion to open surgery (OR 9.40, p = 0.031). Coagulopathy was a significant predictor of mortality (OR 5.01, p = 0.049). Methods: A retrospective, single-center observational study was conducted on 120 patients who underwent laparoscopic surgery between January 2004 and December 2022. Preoperative assessments included endoscopy, imaging, and staging according to the TNM classification. Risk factors were analyzed using univariate and multivariate logistic regression. Conclusions: Laparoscopic gastrectomy is a technically challenging procedure with substantial risks of morbidity and mortality. Identifying modifiable risk factors, such as anemia and coagulopathy, provides opportunities for improved outcomes through preoperative prehabilitation and optimized patient selection.

Introducción. El manejo de la hernia ventral sigue siendo un desafío para los cirujanos. Su reparación mediante técnicas mínimamente invasivas, como la totalmente extraperitoneal (eTEP) laparoscópica, permite una amplia disección del espacio a reparar, una recuperación postoperatoria más rápida, menor dolor postoperatorio y estancia hospitalaria. El abordaje eTEP es un enfoque novedoso que utiliza el espacio retromuscular para colocar material protésico y fortalecer la pared abdominal. El objetivo es describir los resultados a corto plazo de nuestra experiencia inicial con la técnica eTEP en el manejo de las hernias ventrales. Metodología. Estudio observacional, descriptivo, retrospectivo, donde se incluyen pacientes con el diagnóstico de hernia ventral, sometidos a cirugía laparoscópica-eTEP, entre julio-2021 y junio-2022. Resultados. De un total de 21 pacientes, el 61.9% fueron hombres. El 47.6% tenían sobrepeso y el 52.4% obesidad. Estancia hospitalaria media: 1.6 días. El 66.7% fueron hernias incisionales. Las técnicas quirúrgicas realizadas fueron: Rives-Stoppa (71.4%) asociándose liberación del músculo transverso en el 28.6%. El 19% de los pacientes presentaron complicaciones globales y solo uno fue grave, requiriendo reintervención quirúrgica. Se observó la presencia de seroma clínico en el 9.5% y ecográfico en 57.1%. No se evidenciaron hematomas, infección de herida quirúrgica ni casos de recidiva herniaria. Discusión y conclusiones. El abordaje laparoscópico eTEP Rives-Stoppa, asociado o no a separación posterior de componentes, en el manejo de las hernias ventrales ofrece buenos resultados asociando una baja incidencia de complicaciones postoperatorias, corta estancia hospitalaria, baja incidencia de recidivas herniarias, por lo que podría considerarse una técnica segura y efectiva en el tratamiento de las hernias ventrales.