This study evaluates pedestrian continuity in Panama City, analyzing disruptions and the spatial relationship between crossings and transit stations. Using GIS and field validation, pedestrian networks were assessed based on their continuity, defined by well-maintained sidewalks and marked crossings, and discontinuities, caused by absent sidewalks, commercial infrastructure, service stations, and unmarked crossings. Two urban zones with contrasting layouts were analyzed: Zone A, characterized by a regular grid structure, and Zone B, marked by irregular planning. Results indicate that 67.55% of the study network maintains pedestrian continuity. Additionally, 46.79% of the measured distances between bus stops and formal pedestrian crossings exceed 100 m. The average length of continuous paths is 73.37 m in Zone A and 45.60 m in Zone B. Encroachments by businesses are the primary cause of fragmentation, and the study reflects an important impact of car-oriented urban infrastructures on discontinuities, such as service stations. These stations cause average disruptions of 34.69 m per station in Zone B and 27.56 m in Zone A. The research highlights the need for urban planning strategies to ensure pedestrian continuity, particularly in fragmented urban grids, and underscores the importance of an in-depth consideration of continuity in pedestrian network characterization studies.