Esztella Éva Kis

Dr. Esztella Éva Kis


Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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16 December 2025 in Children
Verified
Journal Article
Open access
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KMKrisztina Martha
Krisztina Martha
KOKovács Orsolya
Kovács Orsolya
CDCsaba Dudás
Csaba Dudás
HDHenrietta Dudas
Henrietta Dudas
EKEsztella Éva Kis
Esztella Éva Kis
Background: Early childhood caries (ECC) remains one of the most prevalent chronic conditions among preschool children worldwide. Feeding practices during infancy play a significant role in shaping oral microbial colonization and caries risk. This study aimed to evaluate the association between breastfeeding, artificial feeding, and the occurrence of ECC among children aged 3–5 years. Methods: A cross-sectional clinical and epidemiological study was conducted involving 103 children aged 3–5 years. Parents completed a structured questionnaire. Participants were divided into three groups based on infant feeding history: exclusively breastfed, exclusively artificially fed, and mixed-fed. Clinical oral examinations assessed dmft indices. Statistical analysis included Kruskal–Wallis and Mann–Whitney U tests for dmft scores, Chi-square tests for categorical variables, Spearman correlations, and binary logistic regression to identify predictors of dental caries. Results: Among participants, 43.6% were exclusively breastfed, 41.7% mixed-fed, and 14.5% exclusively artificially fed. The mean dmft index was highest in formula-fed children (4.2 ± 3.78), followed by mixed-fed (2.97 ± 3.19) and breastfed children (1.75 ± 2.99). Kruskal–Wallis analysis showed significant differences in dmft among groups (p = 0.005), with breastfed children having lower dmft than both formula-fed (p = 0.009) and mixed-fed (p = 0.006) children. Caries presence was significantly associated with feeding type (χ2 = 14.00, p = 0.001) and fluoride toothpaste use (χ2 = 7.56, p = 0.023). A weak negative correlation was observed between dmft and breastfeeding duration (ρ = −0.266, p = 0.007). Logistic regression identified longer breastfeeding duration (OR = 0.889, 95% CI: 0.81–0.97, p = 0.010) and use of fluoride toothpaste (OR = 0.323, 95% CI: 0.13–0.81, p = 0.012) as protective factors against dental caries. Parental questionnaire responses suggested prolonged bottle feeding and nocturnal feeding habits as contributing factors. Conclusions: Longer breastfeeding duration and regular use of fluoride toothpaste were associated with lower risk of dental caries in children. Formula feeding was associated with higher dmft scores. Infant feeding practices significantly influence the risk of early childhood caries. Encouraging breastfeeding and educating parents on appropriate weaning and oral hygiene measures may reduce ECC incidence and support better long-term oral health outcomes.

7 May 2025 in Medicina
Verified
Journal Article
Open access
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KMKrisztina Martha
Krisztina Martha
EKEsztella Éva Kis
Esztella Éva Kis
MEMuresan Izabella Eva
Muresan Izabella Eva
AIAndrei Constantin Ioanovici
Andrei Constantin Ioanovici
Background and Objectives: The most common method for treating malocclusions today is fixed orthodontic therapy, during which brackets and tubes are bonded to the surface of the teeth, which makes oral hygiene difficult to maintain. Increased plaque retention, gingival bleeding, and gingivitis can be diagnosed in the early phases of treatment. The periodontal response to plaque accumulation can be explained by quantitative and qualitative changes in the subgingival microbiota. The aim of our research was to investigate the changes in the subgingival microbiota that occurred within 6–8 weeks after bonding when two different orthodontic adhesives were used. Materials and Methods: Thirty patients were followed; molar tubes were bonded with a composite (C) in fifteen cases, and in the other fifteen cases, they were bonded with glass ionomer cementum (GIC). A microbiological sample was taken from the gingival sulcus of the maxillary first molars at the time of appliance placement (T1) and 6–8 weeks (T2) after bonding. Bacterial DNA detection was performed using the micro-IDent®plus11 (Hain Lifescience GmbH, Germany) PCR (polymerase chain reaction) method. The statistical analysis included McNemar’s test to analyze the paired binary data and Fisher’s Exact Test to compare the prevalence of each of the 11 bacteria at T1 and, ultimately, T2 between the two studied groups. The Bonferroni correction was also applied. Results: When analyzing GIC vs. C at T1 and T2, none of the studied pathogens showed significant differences. Conclusions: Given the lack of statistical significance, these trends do not confirm a definitive impact of the procedure on bacterial presence. The increased presence of periodontal pathogens might suggest that bonding does not reduce the bacterial loading of subgingival microbiota. Less protective effects of the GIC intervention against Tannerella forsythia and Eubacterium nodatum bacteria were detected.

26 December 2025 in Epidemiologia
Verified
Journal Article
Open access
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EKEsztella Éva Kis
Esztella Éva Kis
BGBoglárka Ilona Gecse
Boglárka Ilona Gecse
CBCristina Ioana Bica
Cristina Ioana Bica
CDCsaba Dudás
Csaba Dudás
HDHenrietta Dudas
Henrietta Dudas
KMKrisztina Martha
Krisztina Martha
Background: Molar–Incisor Hypomineralization (MIH) represents a developmental enamel defect of systemic origin, typically affecting the first permanent molars and often the incisors. Within the limitations of this study, several associations were observed between perinatal factors and MIH-related outcomes. However, most of these connections were not retained in adjusted analyses. Febrile illness during the first year of life showed a significant association with hypersensitivity. Methods: A structured 30-item questionnaire was distributed to mothers of 50 children diagnosed with MIH between February and March 2024. Data was analyzed using chi-square tests, with p < 0.05 considered significant, and univariate and multivariate logistic regressions at 95% confidence interval. Clinical diagnosis followed the Weerheijm (EAPD) criteria. Results: Maternal medication during pregnancy (antibiotics, antiepileptics, asthma drugs) was significantly associated with preterm birth (p = 0.01). Low birth weight correlated with tooth eruption disorders (p = 0.009) and perinatal complications such as hypoxia and respiratory distress (p = 0.0001). Fluoride application demonstrated a protective effect against discolorations (p = 0.005), caries (p = 0.002), and hypersensitivity (p = 0.01). In the multivariate model, febrile illness during the first year of life may be associated with hypersensitivity in MIH-affected teeth (aOR = 5.71, 95% CI: 1.01–32.27, p = 0.049). Conclusions: Maternal medication and perinatal complications, particularly low birth weight, were associated with MIH occurrence. Preventive strategies emphasizing maternal health, early screening, and remineralization-based therapies can mitigate long-term oral health impacts.

20 June 2025 in Medicina
Verified
Journal Article
Open access
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MEMuresan Izabella Eva
Muresan Izabella Eva
DCDiana Cerghizan
Diana Cerghizan
Attila Levente GergelyAttila Levente Gergely
Attila Levente Gergely
RFRudolf László Farmos
Rudolf László Farmos
LJLászló Jakab-Farkas
László Jakab-Farkas
KMKrisztina Martha
Krisztina Martha
Background and Objectives: Ensuring the optimal shear bond strength (SBS) is essential for the long-term success of prosthodontic restorations. Our in vitro study aimed to evaluate the SBS of three types of ceramics (feldspathic, alumina, and lithium disilicates) using three adhesive cements (Variolink Esthetic LC, Variolink Esthetic DC, and Maxcem Elite). Materials and Methods: Healthy molars were prepared, and ceramic blocks were cemented following universally accepted luting protocols. SBS tests were performed using a custom-made testing machine. A multiple linear regression model assessed the effects of ceramic type, surface treatment, and luting agent on SBS. Results: The regression model explained 61.3% of the variation in SBS values (R2 = 0.613); the adjusted R2 = 0.605 confirmed the model’s robustness. The global F-test was statistically significant (F = 78.96, p < 0.001). The total-etch technique (+4.47), the use of feldspathic ceramic, and 5% hydrofluoric acid treatment (+3.28) significantly affected SBS. Feldspathic ceramic and lithium disilicate showed superior performance against alumina. Light-cured and self-cured cement showed negative effects. Conclusions: Ceramic material and cement type have combined effects on SBS. Optimal results were obtained with the total-etch technique, feldspathic ceramic, 5% hydrofluoric acid treatment, and dual-cured cement.

31 July 2025 in The Romanian Journal of Nutrition
Verified
Journal Article
Closed access
EKEsztella Éva Kis
Esztella Éva Kis
IBIoan-Ovidiu Bocicorec
Ioan-Ovidiu Bocicorec
KMKrisztina Martha
Krisztina Martha
Introduction. Dietary habits and oral hygiene practices play a significant role in the development of dental caries and oral health in childrens lives. This study aims to evaluate the frequency of sugar consumption, oral hygiene practices and parental attitudes concerning preventive dental care. Materials and method. Data were collected using an original questionnaire that addressed nutritional habits, oral hygiene routines and frequency of dental visits among children from Maramureș county, between November 2024 and February 2025. Results. A significant proportion of children (37.57%) consume sugary foods daily, while 47.27% consume them 2-3 times per week. The consumption of sugar-sweetened drinks was moderate, with 51.51% of individuals drinking them occasionally and 20.6% once a week; 22.42% consumed 2-3 times per week carbonated beverages, which are associated with a lower oral pH and with an increased caries risk. Most children (84.24%) predominantly drink water, and 60% consume fresh fruit daily. Unhealthy snacking was reported by 27.27% of children daily, and 27.87% also ate after evening toothbrushing, potentially limiting the effectiveness of oral hygiene. Although 58.78% brush twice daily, only 13.93% use adjunctive oral hygiene aids. Preventive dental visits every six months were reported by 36.96% of children, with 40% attending only for emergencies. Conclusions. Frequent sugar consumption, sugar-sweetened drinks and inadequate oral hygiene contribute significantly to early dental lesions in children. Parental support and educational campaigns are vital for encouraging healthy habits. Promoting balanced nutrition, rigorous oral care and regular dental checkups is essential to improve childrens long-term oral health status.