With the continuous development of artificial intelligence technology, “brain‐computer interfaces” are gradually entering the field of medical rehabilitation. As a result, brain‐computer interfaces (BCIs) have been included in many countries’ strategic plans for innovating this field, and subsequently, major funding and talent have been invested in this technology. In neurological rehabilitation for stroke patients, the use of BCIs opens up a new chapter in “top‐down” rehabilitation. In our study, we first reviewed the latest BCI technologies, then presented recent research advances and landmark findings in BCI‐based neurorehabilitation for stroke patients. Neurorehabilitation was focused on the areas of motor, sensory, speech, cognitive, and environmental interactions. Finally, we summarized the shortcomings of BCI use in the field of stroke neurorehabilitation and the prospects for BCI technology development for rehabilitation.

Brain‐computer interfaces (BCIs), a new type of rehabilitation technology, pick up nerve cell signals, identify and classify their activities, and convert them into computer‐recognized instructions. This technique has been widely used in the rehabilitation of stroke patients in recent years and appears to promote motor function recovery after stroke. At present, the application of BCI in poststroke cognitive impairment is increasing, which is a common complication that also affects the rehabilitation process. This paper reviews the promise and potential drawbacks of using BCI to treat poststroke cognitive impairment, providing a solid theoretical basis for the application of BCI in this area.

Ischemic stroke (IS) is the predominant subtype of stroke and a leading contributor to global mortality. The mitochondrial-associated endoplasmic reticulum membrane (MAM) is a specialized region that facilitates communication between the endoplasmic reticulum and mitochondria, and has been extensively investigated in the context of neurodegenerative diseases. Nevertheless, its precise involvement in IS remains elusive. This literature review elucidates the intricate involvement of MAM in mitophagy and endoplasmic reticulum stress during IS. PINK1, FUNDC1, Beclin1, and Mfn2 are highly concentrated in the MAM and play a crucial role in regulating mitochondrial autophagy. GRP78, IRE1, PERK, and Sig-1R participate in the unfolded protein response (UPR) within the MAM, regulating endoplasmic reticulum stress during IS. Hence, the diverse molecules on MAM operate independently and interact with each other, collectively contributing to the pathogenesis of IS as the covert orchestrator.

Background: Integrated care not only could fix up the fragmental healthcare caused by the ageing of the population, changing of disease spectrum and fast-growing medical scientific knowledge, also improve the continuity of care and the quality of life. Purpose/Objectives: To investigate the growth pattern, languages, core journals, jurisdictions and research domains of integrated care. Methods: Literature search: The Medline/PubMed was searched by using the search strategy "(delivery of health care, integrated [MeSH Terms]) OR integrated care" without time and language limits. Analysis methods: We extract the publishing year, journals, jurisdictions and key words of the retrieved articles. Finally descriptive statistical analysis and hierarchical clustering are used. Results: A total number of 9,090 articles were retrieved. Results included: a) the first article was published in 1947 and the cumulative numbers of the publications on integrated care rose perpendicularly after 1993. b) All documents were recorded by 1,646 kinds of journals. There were 28 core journals. The top 3 were Modern Healthcare, Healthcare Financial Management: Journal of Healthcare Financial Management Association, International Journal of Integrated Care. c) U.S. lead the scientific output (61.91%), followed by the UK (16.84%) and Netherlands(3.59%). d) There are 6 key domains of integrated care, which were the definition and models of integrated care, interdisciplinary patient care team, disease management for chronically ill patients, types of healthcare organizations, information system integration and legislation/jurisprudence.