To date, the only effective means to respond to the spreading of the COVID-19 pandemic are non-pharmaceutical interventions (NPIs), which entail policies to reduce social activity and mobility restrictions. Quantifying their effect is difficult, but it is key to reducing their social and economic consequences. Here, we introduce a meta-population model based on temporal networks, calibrated on the COVID-19 outbreak data in Italy and applied to evaluate the outcomes of these two types of NPIs. Our approach combines the advantages of granular spatial modelling of meta-population models with the ability to realistically describe social contacts via activity-driven networks. We focus on disentangling the impact of these two different types of NPIs: those aiming at reducing individuals’ social activity, for instance through lockdowns, and those that enforce mobility restrictions. We provide a valuable framework to assess the effectiveness of different NPIs, varying with respect to their timing and severity. Results suggest that the effects of mobility restrictions largely depend on the possibility of implementing timely NPIs in the early phases of the outbreak, whereas activity reduction policies should be prioritized afterwards.

Social conventions change when individuals collectively adopt an alternative over the status quo, in a process known as social diffusion. Our repeated trials of a multi-round experiment provided data that helped motivate the proposal of an agent-based model of social diffusion that incorporates inertia and trend-seeking, two behavioural mechanisms that are well documented in the social psychology literature. The former causes people to stick with their current decision, the latter creates sensitivity to population-level changes. We show that such inclusion resolves the contradictions of existing models, allowing to reproduce patterns of social diffusion which are consistent with our data and existing empirical observations at both the individual and population level. The model reveals how the emergent population-level diffusion pattern is critically shaped by the two individual-level mechanisms; trend-seeking guarantees the diffusion is explosive after the diffusion process takes off, but inertia can greatly delay the time to take-off.

Motivated by the literature on opinion dynamics and evolutionary game theory, we propose a novel mathematical framework to model the intertwined coevolution of opinions and decision-making in a complex social system. In the proposed framework, the members of a social community update their opinions and revise their actions as they learn of others’ opinions shared on a communication channel and observe others’ actions through an influence channel; these interactions determine a two-layer network structure. We offer an application of the proposed framework by tailoring it to study the adoption of a novel social norm, demonstrating that the model is able to capture the emergence of several real-world collective phenomena such as paradigm shifts and unpopular norms. Through the establishment of analytical conditions and Monte Carlo numerical simulations, we shed light on the role of the coupling between opinion dynamics and decision-making, and of the network structure, in shaping the emergence of complex collective behavior in social systems.

The spreading dynamics of an epidemic and the collective behavioral pattern of the population over which it spreads are deeply intertwined and the latter can critically shape the outcome of the former. Motivated by this, we design a parsimonious game-theoretic behavioral-epidemic model, in which an interplay of realistic factors shapes the coevolution of individual decision making and epidemics on a network. Although such a coevolution is deeply intertwined in the real world, existing models schematize population behavior as instantaneously reactive, thus being unable to capture human behavior in the long term. Our paradigm offers a unified framework to model and predict complex emergent phenomena, including successful collective responses, periodic oscillations, and resurgent epidemic outbreaks. The framework also allows us to provide analytical insights on the epidemic process and to assess the effectiveness of different policy interventions on ensuring a collective response that successfully eradicates the outbreak. Two case studies, inspired by real-world diseases, are presented to illustrate the potentialities of the proposed model.

Activity-driven networks are a powerful paradigm to study epidemic spreading over time-varying networks. Despite significant advances, most of the current understanding relies on discrete-time computer simulations, in which each node is assigned an activity potential from a continuous distribution. Here, we establish a continuous-time discrete-distribution framework toward an analytical treatment of the epidemic spreading, from its onset to the endemic equilibrium. In the thermodynamic limit, we derive a nonlinear dynamical system to accurately model the epidemic spreading and leverage techniques from the fields of differential inclusions and adaptive estimation to inform short- and long-term predictions. We demonstrate our framework through the analysis of two real-world case studies, exemplifying different physical phenomena and time scales.