Primary pulmonary artery sarcoma is a rare tumor that mimics pulmonary embolism. Patients may present with cough, dyspnea, chest pain, and weight loss. The diagnosis is challenging. Herein, we report a case of 29-year-old female patient who had presented with dyspnea, fatigue for 2 weeks. Computed tomography pulmonary angiography scan suggests pulmonary embolism. We decided to perform surgical embolectomy. The histopathological results, however demonstrated primary pulmonary artery intimal sarcoma. The patient died 1-month post-surgery because of respiratory and circulatory failure.
Dietary calcium’s role in human health and disease prevention is inconclusive. We examined the associations between dietary calcium intake and the risk of overall and specific causes of mortality. A prospective cohort study was performed for 42,146 individuals from 2008 to 2019. Face-to-face interviews used structured semi-quantitative food frequency and demographic lifestyle questionnaires to obtain calcium intake. The cause of 2,494 deaths was determined from medical records. We calculated hazard ratios (HR) and corresponding 95% confidence intervals (95% CI) using a Cox proportional hazards model across eight quantiles of dietary calcium intake. Compared to the reference range 222.5-261.3 mg/day, the lowest dietary calcium intake was associated with an increased mortality risk from all causes, HR (95% CI): 1.22 (1.04, 1.42). In contrast, the highest dietary calcium intake was associated with an increased risk of cancer death, HR (95% CI): 1.43 (1.01, 2.01). By stratified analysis, the lowest dietary calcium intake was associated with an increased risk of mortality from all causes in women, in never smokers, individuals with a BMI < 23 kg/m², never drinkers, no diabetes, no history of hypertension, and no history of cancer. An increased risk of overall mortality and cancer death at the borderline was observed for the lowest and highest calcium intake, respectively. There is a possible U-shaped association between calcium intake and the risk of all causes and cancer. The reference group ranges from 222.5 mg/day to 261.3 mg/day. The findings warrant further research on the association between dietary calcium intake and overall mortality and cancer.
21 November 2025 in Nutrition, Metabolism and Cardiovascular Diseases
Background: ST-elevation myocardial infarction (STEMI) is a life-threatening emergency. Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion strategy, provided it is performed promptly (within 120 min of the ECG-based diagnosis). However, the failure rate of PPCI remains high, particularly in patients with more severe conditions, potentially leading to serious complications. Objective: Through this case, we want to introduce coronary fibrinolysis as a rescue therapy after failing with primary PPCI. Methods: Case report. Results: We reported a clinical case of a STEMI patient who underwent coronary fibrinolysis as a rescue therapy after PPCI failure. The patient was a 62-year-old male patient who was a 40-pack-year smoker. He was diagnosed with STEMI and immediately received PPCI, but the aspiration process and angioplasty were unsuccessful. Subsequently, we decided to use coronary fibrinolysis and the follow-up coronary angiography showed coronary revascularization, and chest pain was resolved. Conclusions: This case highlighted a potential therapeutic approach of coronary fibrinolysis for patients experiencing PPCI failure.
Can thiệp đặt stent động mạch cảnh (ĐMC) là phương pháp ít xâm lấn, tỉ lệ thành công cao và biến chứng thấp. Nghiên cứu nhằm đánh giá kết quả điều trị hẹp động mạch cảnh đoạn ngoài sọ bằng phương pháp can thiệp đặt stent tại Bệnh viện Đại học Y Hà Nội giai đoạn từ 1/2022 tới 8/2025 với tổng số 78 bệnh nhân. Kết quả cho thấy có 85,9% nam giới, tuổi trung bình là 70 tuổi, 64,1% hẹp mạch cảnh có triệu chứng, 78,2% hẹp nặng động mạch cảnh trên chụp động mạch cảnh qua da. Tất cả thủ thuật đều thành công, tỉ lệ đột quỵ thiếu máu não nặng là 1,3%, tỉ lệ xuất huyết não là 1,3%, tỉ lệ biến cố mới trong 30 ngày là 0%. Can thiệp đặt stent động mạch cảnh đoạn ngoài sọ là một thủ thuật tương đối an toàn, ít xâm lấn và hiệu quả với tỷ lệ biến chứng thấp.
Background/Objectives: There has been a growing concern about excessive caffeine consumption among heavy green tea drinkers on health outcomes, such as cardiovascular diseases or cancer. We evaluated the association between green tea consumption and risk of all-cause mortality in Vietnam. Methods: We used data from the Hanoi Prospective Cohort Study, an ongoing study comprising 42,146 participants aged 10 or older in Northern Vietnam who have been followed up between 2007 and 2019. Green tea intake was derived from a validated semi-quantitative food frequency questionnaire. We performed a Cox proportional hazard regression model to calculate the hazard ratio (HR) and respective 95% confidence intervals (95% CIs) for the association between green tea consumption and risk of all-cause mortality, adjusted for potential confounding factor. Results: After a median follow-up of 11 years (range: 0.13–11.64 years), we identified 2494 deaths. Overall, there was an inverse association between green tea intake and risk of all-cause mortality (HRperSDincrement = 0.93; 95% CI, 0.89–0.97, Ptrend < 0.001). This pattern was more pronounced in males (HRperSDincrement = 0.93; 95% CI, 0.89–0.97, Ptrend < 0.001) but not in females (HRperSDincrement = 0.94; 95% CI, 0.86–1.02, Ptrend = 0.12; Pheterogeneity = 0.81). In stratified analysis, the inverse association pattern was seen in both younger and old age groups, in individuals with BMI < 23 kg/m2, in both ever and never smokers, among ever alcohol drinkers and never coffee drinkers, and in individuals with and without history of type 2 diabetes (Pheterogeneity = 0.31). Conclusions: Findings from the current study, the first prospective cohort study in Vietnam, suggest a protective effect of green tea consumption on risk of all-cause mortality. Further studies are warranted to validate our findings in similar population and settings.