Aakanksha Agarwal

Dr. Aakanksha Agarwal


Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 November 2019 in Insights into Imaging
Verified
Journal Article
Open access
PDF file
AAAakanksha Agarwal
Aakanksha Agarwal
ACAbhishek Chandra
Abhishek Chandra
UJUsha Jaipal
Usha Jaipal
MBMeenu Bagarhatta
Meenu Bagarhatta
KMKuldeep Mendiratta
Kuldeep Mendiratta
NMNaresh Mangalhara
Naresh Mangalhara
Purpose: Peripheral neuropathies are a group of disorders which affect the peripheral nervous system which have been conventionally diagnosed using electrodiagnostic studies. This study was carried out to assess the role of imaging in diagnosing peripheral mononeuropathy as exact anatomical localisation of the pathology is possible using high-resolution ultrasound and MR neurography, the modalities assessed in this study. Method: A hospital-based prospective analytical study was carried out in a resource-limited setting on 180 peripheral nerves in 131 patients with symptoms of peripheral mononeuropathy after taking IRB approval. Each patient underwent high-resolution ultrasound examination and MR neurography, findings of which were then compared and statistically analysed assuming electrodiagnostic findings as the gold standard. Results: Overall, the diagnostic accuracy was highest for the proton density fat-saturated MR sequence (93.89%) followed by high-resolution ultrasound (80%). The sensitivity was highest for proton density fat-saturated sequence while the T1 MR sequence had the highest specificity. Combined diagnostic accuracy of both modalities was calculated to be 93.33% with a negative predictive value of 80%. High-resolution ultrasound and MRI equally detected the cases with nerve discontinuity, while neuromas were better identified on MRI. Conclusion: With the advent of higher frequency probes and improved MR field strength, imaging of peripheral nerves is possible with better accuracy. Imaging assessment of nerves allows anatomical delineation with identification of exact site of involvement. This comparative study demonstrates the role of imaging in diagnosing peripheral nerve pathologies with the accuracy of MRI as high as 93.89% which may serve as an imaging gold standard. High-resolution ultrasound, being quicker, cost effective and a comparable accuracy of 80% can serve as a reliable screening tool. This study incorporates a larger study group and compares HRUS with MRI, taking NCV as gold standard, which has not been done in the preceding studies. With this study, we conclude that these two imaging modalities are not mutually exclusive. Rather, they complement each other and can be used in conjunction as an imaging yardstick for diagnosing peripheral neuropathies.

20 March 2019 in Insights into Imaging
Verified
Journal Article
Open access
PDF file
AAAakanksha Agarwal
Aakanksha Agarwal
ACAbhishek Chandra
Abhishek Chandra
UJUsha Jaipal
Usha Jaipal
NSNarender Saini
Narender Saini
The ulnar nerve is a branch of the C8 and T1 nerve roots and arises from the medial cord of the brachial plexus. It supplies the intrinsic muscles of the hand and assists the median nerve in functioning of the flexors. Also known as the musician’s nerve, it is the second most common nerve involved in compressive neuropathy following the median nerve. Common sites of entrapment include cubital tunnel at the elbow, the ulnar groove in the humerus and the Guyon’s canal at the wrist. Patients present with altered sensation in the ulnar fourth and the fifth digit and the medial side of arm with loss of function of intrinsic muscles of the hand, the flexor carpi ulnaris and ulnar fibres of flexor digitorum superficialis in more severe cases. Diagnosis relies on clinical examination, electrodiagnostic studies and imaging findings. Plain radiographs are used to identify fracture sites, callus, or tumours as cause of compression. Technological advances in ultrasonography have allowed direct visualisation of the involved nerve with assessment of exact site, extent and type of injury. It yields unmatched information about anatomical details of the nerve. MR imaging adds to soft tissue details and helps in characterising the lesion. This pictorial review aims to illustrate a wide spectrum of causes of ulnar neuropathies as seen on ultrasound and MRI and emphasises upon the importance of imaging modalities in the diagnosis of neuropathies.

5 November 2018 in Insights into Imaging
Verified
Journal Article
Open access
PDF file
AAAakanksha Agarwal
Aakanksha Agarwal
ACAbhishek Chandra
Abhishek Chandra
UJUsha Jaipal
Usha Jaipal
NSNarender Saini
Narender Saini
The radial nerve has a long and tortuous course in the upper limb. Injury to the nerve can occur due to a multitude of causes at many potential sites along its course. The most common site of involvement is in the proximal forearm affecting the posterior interosseous branch while the main branch of the radial nerve is injured in fractures of the humeral shaft. Signs and symptoms of radial neuropathy depend upon the site of injury. Injury to the nerve distal to innervation of triceps brachii results in loss of extensor function with sparing of function of the triceps resulting in the characteristic ‘wrist drop’. Injury in the mid-arm is associated with loss of sensation in the dorsolateral aspect of the hand, the dorsal aspect of the radial three-and-a-half digits and in the first web space. Involvement of only the posterior interosseous nerve (PIN) results in weakness of the wrist and digit extensors. Diagnosis relies on clinical examination, electrodiagnostic studies and imaging findings. Plain radiographs are used to identify fracture sites, callus or tumours as cause of compression. Technological advances in ultrasonography have allowed direct visualisation of the involved nerve with assessment of the exact site, extent and type of injury. It yields unmatched information about anatomical details of the nerve. MR imaging adds to soft-tissue details and helps in characterising the lesion. This pictorial review aims to illustrate a wide spectrum of causes of radial neuropathy and emphasises the importance of imaging modalities in diagnosis of neuropathies. • Radial nerve injuries are assessed by clinical examination and diagnosed using electrodiagnostic and imaging studies. • Knowledge of anatomical relations and course of the nerve is necessary to identify the nerve at pre-determined anatomical locations. • Altered echogenicity and signal intensity, discontinuity of the nerve, focal thickening and cause of compression can be assessed by imaging modalities. • MR imaging helps in confirmation of the ultrasound findings, differentiating similar appearing lesions and provides additional soft-tissue details.

28 February 2025 in Diagnostics
Verified
Journal Article
Open access
PDF file
SSSonal Saran
Sonal Saran
SPSaavi Reddy Pellakuru
Saavi Reddy Pellakuru
KSKAPIL SHIRODKAR
KAPIL SHIRODKAR
ASAnkit B. Shah
Ankit B. Shah
AAAakanksha Agarwal
Aakanksha Agarwal
RBRajesh Botchu
Rajesh Botchu
Guyon’s canal, or the ulnar tunnel, is a critical anatomical structure at the wrist that houses the ulnar nerve and artery, making it susceptible to various pathological conditions. Pathologies affecting this canal include traumatic injuries, compressive neuropathies like ulnar tunnel syndrome, and space-occupying lesions such as ganglion cysts. Ulnar tunnel syndrome, characterised by numbness, tingling, and weakness in the ulnar nerve distribution, is a prevalent condition that can severely impair hand function. The canal’s intricate anatomy is defined by surrounding ligaments and bones, divided into three zones, each containing distinct neural structures. Variations, including aberrant muscles and vascular anomalies, can complicate diagnosis and treatment. Imaging techniques are essential for evaluating these conditions; ultrasound provides real-time, dynamic assessments, while magnetic resonance imaging (MRI) offers detailed visualisation of soft tissues and bony structures, aiding in pre-surgical documentation and pathology evaluation. This review article explores the anatomy, pathologies, and imaging modalities associated with Guyon’s canal and underscores the necessity of understanding Guyon’s canal’s anatomy and associated pathologies to improve diagnostic accuracy and management strategies. By integrating anatomical insights with advanced imaging techniques, clinicians can enhance patient outcomes and preserve hand function, emphasising the need for increased awareness and research in this often-neglected area of hand anatomy.

3 December 2024 in Skeletal Radiology
Verified
Journal Article
Closed access
PDF file
AAAakanksha Agarwal
Aakanksha Agarwal
ACAbhishek Chandra
Abhishek Chandra
KSKAPIL SHIRODKAR
KAPIL SHIRODKAR
ASAnkit Shah
Ankit Shah
TMTimothy E. Murray
Timothy E. Murray
RBRajesh Botchu
Rajesh Botchu

17 June 2023 in Indian Journal of Musculoskeletal Radiology
Verified
Journal Article
Open access
AAAakanksha Agarwal
Aakanksha Agarwal
ACAbhishek Chandra
Abhishek Chandra
TMTimothy Murray
Timothy Murray
QAQuamar Azam
Quamar Azam
Objectives: The study aimed to identify the Kaplan fiber (KF) complex, focusing on the condylar strap (CS) which are fiber straps on the lateral aspect of the knee related to the iliotibital complex, on magnetic resonance imaging (MRI) of knees performed for acute anterior cruciate ligament (ACL) injury, measure the distances of insertion from the lateral joint line, and identify injuries to these structures. Material and Methods: Retrospective analysis of 134 MRIs of knees with acute ACL tear was performed. The proximal and distal KFs and the CS were identified on at least one plane on MRI. The distance of their femoral attachment from the lateral joint line and injury to these structures with concomitant knee injuries was documented. Data analysis was performed using the SPSS software. Results: KFs were identified in 97.2% and CS in 72% of the MRI knees. The mean distance of the proximal KF from the lateral joint line was 59.1 mm, while that of the distal KF was 42.4 mm. The CS attached 35.6 mm proximal to the lateral joint line. KF complex injury was present in 34% of cases with ACL tear. The MRI finding of meniscal tear and bone marrow edema in a classic pivot shift impaction injury pattern had a significant positive correlation with KF injury. Conclusion: This radiological study confirms the existence of CS on MRI. There is a positive association of KF injury with meniscal tears and bone marrow edema in patients with acute ACL tears. Future biomechanical studies focusing on CS are needed to identify its contribution to anterolateral stability.