The standard method for prediction of the absence and presence of pain has long been self-report. However, for patients with major cognitive or communicative impairments, it would be better if clinicians could quantify pain without having to rely on the patient’s self-description. Here, we present a newly pain intensity measurement method based on multiple physiological signals, including blood volume pulse (BVP), electrocardiogram (ECG) and skin conductance (SC), all of which are induced by external electrical stimulation. The proposed pain prediction system consists of signal acquisition and preprocessing, feature extraction, feature selection and feature reduction, and three types of pattern classifiers. Feature extraction phase is devised to extract pain-related characteristics from short-segment signals. A hybrid procedure of genetic algorithm-based feature selection and principal component analysis-based feature reduction was established to obtain high-quality features combination with significant discriminatory information. Three types of classification algorithms—linear discriminant analysis, k-nearest neighbor algorithm, and support vector machine—are adopted during various scenarios, including multi-signal scenario, multi-subject and between-subject scenario, and multi-day scenario. The classifiers gave correct classification ratios much higher than chance probability, with the overall average accuracy of 75% above for four pain intensity. Our experimental results demonstrate that the proposed method can provide an objective and quantitative evaluation of pain intensity. The method might be used to develop a wearable device that is suitable for daily use in clinical settings.

Traditional myoelectric prostheses that employ a static pattern recognition model to identify human movement intention from surface electromyography (sEMG) signals hardly adapt to the changes in the sEMG characteristics caused by interferences from daily activities, which hinders the clinical applications of such prostheses. In this study, we focus on methods to reduce or eliminate the impacts of three types of daily interferences on myoelectric pattern recognition (MPR), i.e., outlier motion, muscle fatigue, and electrode doffing/donning. We constructed an adaptive incremental hybrid classifier (AIHC) by combining one-class support vector data description and multi-class linear discriminant analysis in conjunction with two specific update schemes. We developed an AIHC-based MPR strategy to improve the robustness of MPR against the three interferences. Extensive experiments on hand-motion recognition were conducted to demonstrate the performance of the proposed method. Experimental results show that the AIHC has significant advantages over non-adaptive classifiers under various interferences, with improvements in the classification accuracy ranging from 7.1% to 39% (p<0.01). The additional evaluations on data deviations demonstrate that the AIHC can accommodate largescale changes in the sEMG characteristics, revealing the potential of the AIHC-based MPR strategy in the development of clinical myoelectric prostheses.

It has been clinically proven that exoskeletons are effective self-training rehabilitation or daily living assistance devices for patients with hand dysfunctions. However, exoskeleton-assisted hand exercises with high degrees-of-freedom are considered as challenging tasks because the digit space, especially the thumb, cannot accommodate enough actuators. In this article, we report a tendon-driven soft hand exoskeleton with a hybrid configuration for thumb actuation. The soft hand exoskeleton system uses the least number of actuators to realize full degrees-of-freedom actuation for all digits. It is tested on a stroke patient with hemiplegia and a healthy subject. The experimental results show that the hand exoskeleton could assist the stroke patient to accomplish various training tasks, such as thumb encircling, grasping, pinching, releasing, and writing. It was found that digit trajectories and joint angle changes of the stroke patient were close to those of the healthy subject. Especially, the range of motion of the stroke patient shows significant improvement with the hand exoskeleton assistance compared to that without the hand exoskeleton assistance. The research in this article paves the way to develop fully actuated soft hand exoskeleton that can be eventually integrated with an electroencephalogram or electromyography for self-training rehabilitation or daily living assistance.

In order to reduce the gap between the laboratory environment and actual use in daily life of human-machine interaction based on surface electromyogram (sEMG) intent recognition, this paper presents a benchmark dataset of sEMG in non-ideal conditions ( SeNic ). The dataset mainly consists of 8-channel sEMG signals, and electrode shifts from an 3D-printed annular ruler. A total of 36 subjects participate in our data acquisition experiments of 7 gestures in non-ideal conditions, where non-ideal factors of 1) electrode shifts, 2) individual difference, 3) muscle fatigue, 4) inter-day difference, and 5) arm postures are elaborately involved. Signals of sEMG are validated first in temporal and frequency domains. Results of recognizing gestures in ideal conditions indicate the high quality of the dataset. Adverse impacts in non-ideal conditions are further revealed in the amplitudes of these data and recognition accuracies. To be concluded, SeNic is a benchmark dataset that introduces several non-ideal factors which often degrade the robustness of sEMG-based systems. It could be used as a freely available dataset and a common platform for researchers in the sEMG-based recognition community. The benchmark dataset SeNic are available online via the website ( https://github.com/bozhubo/SeNic and https://gitee.com/bozhubo/SeNic ).

A long history has passed since electromyography (EMG) signals have been explored in human-centered robots for intuitive interaction. However, it still has a gap between scientific research and real-life applications. Previous studies mainly focused on EMG decoding algorithms, leaving a dynamic relationship between the human, robot, and uncertain environment in real-life scenarios seldomly concerned. To fill this gap, this paper presents a comprehensive review of EMG-based techniques in human-robot-environment interaction (HREI) systems. The general processing framework is summarized, and three interaction paradigms, including direct control, sensory feedback, and partial autonomous control, are introduced. EMG-based intention decoding is treated as a module of the proposed paradigms. Five key issues involving precision, stability, user attention, compliance, and environmental awareness in this field are discussed. Several important directions, including EMG decomposition, robust algorithms, HREI dataset, proprioception feedback, reinforcement learning, and embodied intelligence, are proposed to pave the way for future research. To the best of what we know, this is the first time that a review of EMG-based methods in the HREI system is summarized. It provides a novel and broader perspective to improve the practicability of current myoelectric interaction systems, in which factors in human-robot interaction, robot-environment interaction, and state perception by human sensations are considered, which has never been done by previous studies.

High accuracy decoding of electroencephalogram (EEG) signal is still a major challenge that can hardly be solved in the design of an effective motor imagery-based brain-computer interface (BCI), especially when the signal contains various extreme artifacts and outliers arose from data loss. The conventional process to avoid such cases is to directly reject the entire severely contaminated EEG segments, which leads to a drawback that the BCI has no decoding results during that certain period. In this study, a novel decoding scheme based on the combination of Lomb-Scargle periodogram (LSP) and deep belief network (DBN) was proposed to recognize the incomplete motor imagery EEG. Particularly, instead of discarding the entire segment, two forms of data removal were adopted to eliminate the EEG portions with extreme artifacts and data loss. The LSP was utilized to steadily extract the power spectral density (PSD) features from the incomplete EEG constructed by the remaining portions. A DBN structure based on the restricted Boltzmann machine (RBM) was exploited and optimized to perform the classification task. Various comparative experiments were conducted and evaluated on simulated signal and real incomplete motor imagery EEG, including the comparison of three PSD extraction methods (fast Fourier transform, Welch and LSP) and two classifiers (DBN and support vector machine, SVM). The results demonstrate that the LSP can estimate relative robust PSD features and the proposed scheme can significantly improve the decoding performance for the incomplete motor imagery EEG. This scheme can provide an alternative decoding solution for the motor imagery EEG contaminated by extreme artifacts and data loss. It can be beneficial to promote the stability, smoothness and maintain consecutive outputs without interruption for a BCI system that is suitable for the online and long-term application.