Objective: To investigate whether platelet‐rich plasma (PRP) has an efficacy on histopathologic changes in rhinitis medicamentosa (RM) in a rat model.Study Design: Experimental animal study.Setting: University animal laboratory.Methods: Forty Wistar albino rats were randomly assigned to five groups to assess the effects of various treatments on RM. Group 1 received intranasal normal saline solution (NSS) for 60 days and served as the negative control. Group 2 was administered intranasal oxymetazoline for 60 consecutive days to induce RM. After decapitation, histopathological evaluation confirmed the development of RM in group 2. The remaining three groups were then similarly treated with oxymetazoline for 60 days. Following this period, group‐specific treatments were applied for an additional 15 days: group 3 received NSS, group 4 was treated with intranasal corticosteroids, and group 5 received intranasal PRP. Nasal mucosal samples were harvested and subjected to histopathological evaluation to determine treatment‐related changes.Results: Intranasal PRP treatment significantly reduced submucosal edema and improved submucosal gland degeneration (SGD) scores in the nasal mucosa. Moreover, PRP treatment led to a greater reduction in total histopathological score compared to steroid treatment (P = .007).Conclusion: This study demonstrated that PRP administration effectively ameliorates submucosal edema, SGD, and total histopathologic score in experimentally induced RM. Given that PRP is an autologous product with a low risk of side effects, it may serve as a promising alternative to steroids in the treatment of RM.

Aim: This study aims to evaluate the effect of infraorbital region taping on patients’ postoperative edema and ecchymosis, satisfaction levels, and anxiety during follow-up. Methods: A total of 64 patients who underwent septorhinoplasty were included in this randomized controlled prospective study. According to the randomization list, the taping group's (TG) infraorbital region was taped with adhesive strips. Others were included in the control group and were classified as the nontaping group. Two blinded physicians evaluated the degree of edema and ecchymosis according to the photographs of patients taken on the first, second, fifth, and seventh postoperative days. Patient's appearance satisfaction was evaluated for ecchymosis levels. State anxiety inventory (STAI-S) and trait anxiety inventory (STAI-T) were used to measure preoperative and postoperative anxiety levels of patients. Results: The degree of ecchymosis and edema were not significantly different except on the first day in the TG (P = 0.01, P = 0.01, respectively). Significant increment was found in the TG on first, second, and fifth days based on the satisfaction levels of patients for their appearance (P = 0.05, P = 0.03, P = 0.04, respectively). Preoperative STAI-S and STAI-T were similar for the groups (P = 0.78, P = 0.17, respectively). However, postoperative STAI-S of the TG were significantly lower compared with those of the nontaping group except seventh day (P < 0.05). Conclusion: Infraorbital taping did not decrease the edema and ecchymosis except on the first postoperative day. However, it had a significant ameliorating effect on patients’ anxiety and satisfaction levels.