Dimethyl fumarate (DMF) has recently gained attention due to its use as a pro-drug in different pharmaceutical preparations, here in we present our work on a cascade methodology in short reaction times and quantitative yields.

Experimental validation was given to molecular dynamics calculations regarding the preferential retention of sulfate ions in the calcite polymorph of calcium carbonate.

A catalyst free decarboxylative trichloromethylation of imines to afford different trichloromethyl sulfonyl and sulfinyl amines has been presented.

To avoid gas hydrate formation during oil and gas production, companies usually employ thermodynamic inhibitors consisting of hydroxyl compounds, such as monoethylene glycol (MEG). However, these inhibitors may cause other types of fouling during production such as inorganic salt deposits (scale). Calcium carbonate is one of the main scaling salts and is a great concern, especially for the new pre-salt wells being explored in Brazil. Hence, it is important to understand how using inhibitors to control gas hydrate formation may be interacting with the scale formation process. Multiple regression and design of experiments were used to mathematically model the calcium carbonate scaling process and its evolution in the presence of MEG. It was seen that MEG, although inducing the precipitation by increasing the supersaturation ratio, actually works as a scale inhibitor for calcium carbonate in concentrations over 40%. This effect was not due to changes in the viscosity, as suggested in the literature, but possibly to the binding of MEG to the CaCO₃ particles’ surface. The interaction of the MEG inhibition effect with the system’s variables was also assessed, when temperature’ and calcium concentration were more relevant.