Skin cancer is a type of cancer disease in which abnormal alterations in skin characteristics can be detected. It can be treated if it is detected early. Many artificial intelligence-based models have been developed for skin cancer detection and classification. Considering the development of numerous models according to various scenarios and selecting the optimum model was rarely considered in previous works. This study aimed to develop various models for skin cancer classification and select the optimum model. Convolutional neural networks (CNNs) in the form of AlexNet, Inception V3, MobileNet V2, and ResNet 50 were used for feature extraction. Feature reduction was carried out using two algorithms of the grey wolf optimizer (GWO) in addition to using the original features. Skin cancer images were classified into four classes based on six machine learning (ML) classifiers. As a result, 51 models were developed with different combinations of CNN algorithms, without GWO algorithms, with two GWO algorithms, and with six ML classifiers. To select the optimum model with the best results, the multicriteria decision-making approach was utilized to rank the alternatives by perimeter similarity (RAPS). Model training and testing were conducted using the International Skin Imaging Collaboration (ISIC) 2017 dataset. Based on nine evaluation metrics and according to the RAPS method, the AlexNet algorithm with a classical GWO yielded the optimum model, achieving a classification accuracy of 94.5%. This work presents the first study on benchmarking skin cancer classification with many models. Feature reduction not only reduces the time spent on training but also improves classification accuracy. The RAPS method has proven its robustness in the problem of selecting the best model for skin cancer classification.

Malaria remains a critical global health challenge, particularly in tropical and subtropical regions. While traditional methods for diagnosis are effective, they face some limitations related to accuracy, time consumption, and manual effort. This study proposes an advanced, automated diagnostic framework for malaria detection using a multi-model architecture integrating deep learning and machine learning techniques. The framework employs a transfer learning approach that incorporates ResNet 50, VGG16, and DenseNet-201 for feature extraction. This is followed by feature fusion and dimensionality reduction via principal component analysis. A hybrid scheme that combines support vector machine and long short-term memory networks is used for classification. A majority voting mechanism aggregates outputs from all models to enhance prediction robustness. The approach was validated on a publicly available dataset comprising 27,558 microscopic thin blood smear images. The results demonstrated superior performance, achieving an accuracy of 96.47%, sensitivity of 96.03%, specificity of 96.90%, precision of 96.88%, and F1-score of 96.45% using the majority voting ensemble. Comparative analysis highlights the framework’s advancements over existing methods in diagnostic reliability and computational efficiency. This work underscores the potential of AI-driven solutions in advancing malaria diagnostics and lays the foundation for applications in other blood-borne diseases.

The incidence of vision impairment is rapidly increasing. Diagnosis and classifying retinal abnormalities in ophthalmological applications is a significant challenge. Using Optical Coherence Tomography (OCT), the study aims to develop a computer aided diagnosis system for detecting and classifying retinal disorders. Choroidal neovascularization, diabetic macular edema, drusen, and normal cases are the investigated groups. Both deep learning and machine learning are combined to build the system. The SqueezeNet neural network was modified to extract features. The Support Vector Machine (SVM), K-Nearest Neighbor (K-NN), Decision Tree (DT), and Ensemble Model (EM) algorithms were used for disorder classification. The Bayesian optimization technique was also used to determine the best hyperparameters for each model. The model’ performance was evaluated through nine criteria using 12,000 OCT images. The results have demonstrated accuracies of 97.39, 97.47, 96.98, and 95.25% for the SVM, K-NN, DT, and EM, respectively. When results are compared to relevant studies in terms of accuracy and tested samples, they show superior performance. As a result, a novel computer-aided diagnosis system for detecting and classifying retinal diseases has been developed, reducing human error while also saving time.

Neurological disorders affect the nervous system and can impair physical, cognitive, or emotional functions. They often result in challenges such as movement difficulties and the inability to perform daily activities. Common conditions include stroke, traumatic brain injury, and cerebral palsy. Physical therapy is a common approach to managing these disorders. Recently, virtual reality (VR), a technology that creates interactive, simulated environments, has been used in rehabilitation. This study presents a rehabilitative game-based system to improve patients’ movements and cognitive abilities. Six games were designed using the Unity platform, namely, “Piano,” “Connect,” “Drag & Drop,” “Little Intelligent,” “Memory,” and “Hack & Slash.” The Oculus Quest 2 VR headset was used to simulate the virtual environment for gaming. A mobile application called “Recover Me” was created to facilitate communication between patients and physiotherapists. A score index was generated for each patient, indicating the performance. It enables monitoring and assessment of the patients, leading to customizing the treatment plan based on progress. The study proposed simulating monitoring and evaluation of the patients by training an artificial neural network model to predict scores for the developed games and consequently indicate the patient’s actual status. A dataset of 50 patients with different injuries was used. Results indicate patient satisfaction with gaming and enjoyment. Moreover, a regression analysis was performed to detect the progress level of each patient, indicating that 60% of the tested patients had improved. A low-cost VR game-based system has proven effective in rehabilitating neurological disorders.

Many automated diagnosis models are designed to classify retinal disease using the Optical Coherence Tomography images. The challenge is how to benchmark such diagnosis models to enable the decision-maker to select the superior diagnosis model. This problem is rarely tackled in the literature. This study aims to evaluate and benchmark the automated diagnosis models of retinal disease to select a superior model. Multi-Criteria Decision-Making-based platform has been proposed to address this issue employing a set of nine quantitative criteria. By examining the underlined research, and according to the proposed criteria, only five models have been selected for the benchmarking. The platform has been designed using the Entropy-Technique for Order Preference by Similarity to Ideal Solution (Entropy-TOPSIS) method. The Entropy is used to find the weights of the criteria; meanwhile, the TOPSIS is implemented to find the ranking order of the models. The results of benchmarking yielded that the EfficientNet-B7 Convolutional Neural Network is the superior classifier with a closeness coefficient of 0.999 of the data set. Adopting an efficient platform for classifying retinal disorders promotes a reliable and fast diagnosis model in terms of reducing human errors and saving time. Furthermore, the study highlights the significance of some new criteria.