Evangelos Christodoulou

Dr. Evangelos Christodoulou


Research Focus & Metrics

Academic Career Length

18Years (2009-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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16 July 2009 in Scoliosis and Spinal Disorders
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Journal Article
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PAPetros D Antonarakos
Petros D Antonarakos
LKLabrini Katranitsa
Labrini Katranitsa
LALefteris Angelis
Lefteris Angelis
APAristofanis Paganas
Aristofanis Paganas
EKErrikos M Koen
Errikos M Koen
ACAnastasios Christodoulou
Anastasios Christodoulou
The SRS-22 is a valid instrument for the assessment of the health related quality of life of patients with Idiopathic scoliosis. The SRS-22 questionnaire was developed in USA and has been widely used in the English speaking countries. Recently it has been translated and validated in many other languages. The purpose of this study is to evaluate the reliability and validity of the adapted Greek version of the refined Scoliosis Research Society-22 Questionnaire.

1 May 2015 in Scoliosis
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Journal Article
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ECEvangelos Christodoulou
Evangelos Christodoulou
SCSuresh Chinthakunta
Suresh Chinthakunta
DRDivya Reddy
Divya Reddy
SKSaif Khalil
Saif Khalil
TATHOMAS APOSTOLOU
THOMAS APOSTOLOU
KKKonstantinos Kafchitsas
Konstantinos Kafchitsas
The pullout strength of pedicle screws is influenced by many factors, including diameter of the screws, implant design, and augmentation with bone cement such as PMMA. In the present study, the pullout strength of an innovative fenestrated screw augmented with PMMA was investigated and was compared to unaugmented fenestrated, standard and dual outer diameter screw. Twenty four thoracolumbar vertebrae (T10-L5, age 60 to 70 years) from three cadavers were implanted with the four different pedicle screws. Twelve screws of each type were instrumented into either left or right pedicle with standard screw paired with unaugmented and dual outer diameter screw paired with augmented fenestrated screw in any given vertebra. Axial pullout testing was conducted at a rate of 5 mm/min. Force to failure (Newtons) for each pedicle screw was recorded. The augmented fenestrated screws had the highest pullout strength, which represented an average increase of 149%, 141%, and 78% in comparison to unaugmented, standard, and dual outer diameter screws, respectively. Pullout strength of unaugmented screws was comparable to that of standard screws, however it was significantly lower than dual outer diameter screws. Fenestrated screws augmented with PMMA improve the fixation strength and result in significantly higher pullout strength compared to dual outer diameter, standard and unaugmented fenestrated screws. Screws with dual outer diameter provided enhanced bone-screw purchase and may be considered as an alternative technique to increase the bone-screw interface in cases where augmentation using bone cement is not feasible. Unaugmented screws can be left in the pedicle even without cement and provide similar pullout strength to standard screws.

14 October 2016 in Scoliosis and Spinal Disorders
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Journal Article
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Theodoros GrivasTheodoros Grivas
Theodoros Grivas
RBR. Geoffrey Burwell
R. Geoffrey Burwell
VKVasileios Kechagias
Vasileios Kechagias
CMChristina Mazioti
Christina Mazioti
AFApostolos Fountas
Apostolos Fountas
ECEvangelos Christodoulou
Evangelos Christodoulou
The historical view of scoliosis as a primary rotation deformity led to debate about the pathomechanic role of paravertebral muscles; particularly multifidus, thought by some to be scoliogenic, counteracting, uncertain, or unimportant. Here, we address lateral lumbar curves (LLC) and suggest a pathomechanic role for quadrates lumborum, (QL) in the light of a new finding, namely of 12th rib bilateral length asymmetry associated with idiopathic and small non-scoliosis LLC. Group 1: The postero-anterior spinal radiographs of 14 children (girls 9, boys 5) aged 9–18, median age 13 years, with right lumbar idiopathic scoliosis (IS) and right LLC less that 10°, were studied. The mean Cobb angle was 12° (range 5–22°). Group 2: In 28 children (girls 17, boys 11) with straight spines, postero-anterior spinal radiographs were evaluated similarly to the children with the LLC, aged 8–17, median age 13 years. The ratio of the right/left 12th rib lengths and it’s reliability was calculated. The difference of the ratio between the two groups was tested; and the correlation between the ratio and the Cobb angle estimated. Statistical analysis was done using the SPSS package. The ratio’s reliability study showed intra-observer +/−0,036 and the inter-observer error +/−0,042 respectively in terms of 95 % confidence limit of the error of measurements. The 12th rib was longer on the side of the curve convexity in 12 children with LLC and equal in two patients with lumbar scoliosis. The 12th rib ratios of the children with lumbar curve were statistically significantly greater than in those with straight spines. The correlation of the 12th rib ratio with Cobb angle was statistically significant. The 12th thoracic vertebrae show no axial rotation (or minimal) in the LLC and no rotation in the straight spine group. It is not possible, at present, to determine whether the 12th convex rib lengthening is congenitally lengthened, induced mechanically, or both. Several small muscles are attached to the 12th ribs. We focus attention here on the largest of these muscles namely, QL. It has attachments to the pelvis, 12th ribs and transverse processes of lumbar vertebrae as origins and as insertions. Given increased muscle activity on the lumbar curve convexity and similar to the interpretations of earlier workers outlined above, we suggest two hypotheses, relatively increased activity of the right QL muscle causes the LLCs (first hypothesis); or counteracts the lumbar curvature as part of the body’s attempt to compensate for the curvature (second hypothesis). These hypotheses may be tested by electrical stimulation studies of QL muscles in subjects with lumbar IS by revealing respectively curve worsening or correction. We suggest that one mechanism leading to relatively increased length of the right 12 ribs is mechanotransduction in accordance with Wolff’s and Pauwels Laws.

28 April 2025 in Healthcare
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Journal Article
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Theodoros GrivasTheodoros Grivas
Theodoros Grivas
ACAnastasios Christodoulou
Anastasios Christodoulou
ECEvangelos Christodoulou
Evangelos Christodoulou
GKGalateia Katzouraki
Galateia Katzouraki
MLMarios G. Lykissas
Marios G. Lykissas
Elias VasiliadisElias Vasiliadis
Elias Vasiliadis
This opinion article refers to the “double rib contour sign” and to the rib index (DRCS and RI), to their reliability study results in the chest radiographs of a control group and to their validity study results. These two parameters were introduced by the first author in this report. The introduction of the Segmental Rib Index (SRI) and its relation to spinal deformity is also discussed. The RI has been confirmed to be a strong surrogate for scoliometric readings in idiopathic scoliosis (IS). The clinical applications of the RI are analyzed for the following: (a) the documentation of deformity; (b) the assessment of physiotherapy outcomes (PSSEs); (c) the documentation of the outcomes of brace treatment; (d) the documentation of the pre- and post-operative assessment of thoracic deformity correction in different types of instrumentation; (e) its usage in prognosticating accelerated deterioration in skeletally mature adolescent idiopathic scoliosis (AIS) curves of 40–50 degrees; and (f) its usage in the recognition of the proper rib level for thoracoplasty/costoplasty. The emerging etiological–scoliogenic implications from the use of the DRCS and RI are described. The rotation of the trunk and vertebral bodies as interrelated, but distinct parameters are finally analyzed.

13 June 2016 in European Spine Journal
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Journal Article
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Theodoros GrivasTheodoros Grivas
Theodoros Grivas
RBR. G. Burwell
R. G. Burwell
VKV. Kechagias
V. Kechagias
CMC. Mazioti
C. Mazioti
AFA. Fountas
A. Fountas
ECEvangelos Christodoulou
Evangelos Christodoulou

1 January 2026 in Case Reports in Neurological Medicine
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Journal Article
Open access
ECEvangelos Christodoulou
Evangelos Christodoulou
KKKonstantinos Kafchitsas
Konstantinos Kafchitsas
We report the case of a 78‐year‐old male presenting with debilitating left‐sided S1 radicular pain, associated with a positive Lasègue sign and numbness in the S1 dermatome. The patient exhibited mild motor deficits, but his pain was severe enough to impair standing and ambulation. Magnetic resonance imaging (MRI) revealed a cystic lesion at the S1 level; however, the exact etiology remained unclear—differential diagnoses included a Tarlov cyst or a facet joint cyst. No other spinal comorbidities were noticed. Initial conservative management, including intravenous analgesics and C‐arm–guided S1 nerve root blocks, failed to provide relief. Due to persistent symptoms, surgical exploration was undertaken. Intraoperatively, a facet joint cyst was identified and successfully excised. Postoperative recovery was uneventful, and the patient reported significant pain relief and functional improvement. This case highlights an unusual presentation of a facet joint cyst located at the sacral level without a visible connection to the facet joint, raising diagnostic challenges on imaging.