Laura Haefliger

Mr. Laura Haefliger

orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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10 March 2022 in Cancers
Verified
Journal Article
Open access
PDF file
NVNaïk Vietti-Violi
Naïk Vietti-Violi
RHRami Hajri
Rami Hajri
LHLaura Haefliger
Laura Haefliger
MLMarie Nicod Lalonde
Marie Nicod Lalonde
NVNicolas Villard
Nicolas Villard
CDClarisse Dromain
Clarisse Dromain
Oligometastatic disease (OMD) is an emerging state of disease with limited metastatic tumor burden. It should be distinguished from polymetastatic disease due the potential curative therapeutic options of OMD. Imaging plays a pivotal role in the diagnosis and follow-up of patients with OMD. The imaging tools needed in the case of OMD will differ according to different parameters, which include primary tumor type, timing between measurement and treatment, potential metastatic location and the patient’s individual risk for metastasis. In this article, OMD is defined and the use of different imaging modalities in several oncologic situations are described in order to better understand OMD and its specific implication for radiologists.

17 April 2025 in Cancers
Verified
Journal Article
Open access
PDF file
LHLaura Haefliger
Laura Haefliger
PCPauline Chapellier
Pauline Chapellier
NVNaïk Vietti-Violi
Naïk Vietti-Violi
JLJean-Baptiste LEDOUX
Jean-Baptiste LEDOUX
SMStyliani Mantziari
Styliani Mantziari
CDClarisse Dromain
Clarisse Dromain
This review provides an in-depth analysis and comprehensive overview of recent advancements in MRI techniques for evaluating esophageal cancer (EC). It discusses the specific MRI acquisition protocols and parameters that enhance image quality and diagnostic accuracy. The review highlights MRI’s role and performance in the initial TNM staging and its potential to refine treatment strategies by improving tumor delineation and characterization. Additionally, the paper explores MRI utility in restaging after NAT, focusing on its accuracy in assessing treatment response and detecting residual or recurrent disease. Comparisons with other imaging modalities currently used—such as endoscopic ultrasound (EUS), contrast-enhanced computed tomography (CE-CT), and 18F-fluorodeoxyglucose (FDG) positron emission tomography/CT (PET/CT)—are included to highlight the strengths and limitations of each method. Illustrated with numerous Figures, this article proposes a novel MRI-based strategy for EC staging and restaging. It aims to integrate MRI into clinical practice by leveraging its superior soft-tissue contrast and functional imaging capabilities to enhance diagnostic precision and improve patient outcomes. Through this comprehensive evaluation, the review underscores the potential of MRI to become a cornerstone in the precision diagnosis and management of EC.

20 July 2023 in European Journal of Radiology
Verified
Journal Article
Open access
LHLaura Haefliger
Laura Haefliger
MJMario Jreige
Mario Jreige
CPCéline Du Pasquier
Céline Du Pasquier
JLJean-Baptiste Ledoux
Jean-Baptiste Ledoux
DWDorothea Wagner
Dorothea Wagner
CDClarisse Dromain
Clarisse Dromain
To evaluate the added value of cine MR in addition to static MRI for T-Staging assessment of esophageal cancer (EC). This prospective monocentric study included 54 patients (mean age 66.3 ± 9.4 years, 46 men) with histologically proven EC. They underwent MRI on a 3 T-scanner in addition to the standard workup. Acquisitions included static and cine sequences (steady-state-free-precession and real-time True-FISP during water ingestion). Three radiologists independently assessed T-staging and diagnosis confidence by reviewing (1) static sequences (S-MRI) and (2) adding cine sequences (SC-MRI). Inter-reader agreement was performed. MRI T-staging was correlated to reference standard T-staging (histopathology or consensus on endoscopic ultrasonography and imaging findings) and to clinical outcome by log-rank test. Both S-MRI and SC-MRI T-staging showed a significant correlation with reference T-staging (rs = 0.667, P < 0.001). SC-MRI showed a slightly better performance in distinguishing T1-T3 from T4 with a sensitivity, specificity and AUC of 76.5% (95% CI: 50.1-93.2), 83.8% (68-93.8) and 0.801 (0.681-0.921) vs 70.6% (44-89.7), 83% (68-93.8) and 0.772 (0.645-0.899) for S-MRI. Compared to S-MRI, SC-MRI increased inter-reader agreement for T4a and T4b (κ = 0.403 and 0.498) and T-staging confidence. MRI is accurate for T-staging of EC. The addition of cine sequences allows better differentiation between T1-T3 and T4 tumors with increased diagnostic confidence and inter-reader agreement.

1 March 2026 in Radiology
Verified
Journal Article
Closed access
GDGary Doppelt
Gary Doppelt
BOBob-Valéry Occéan
Bob-Valéry Occéan
PFPascale Fabbro-Peray
Pascale Fabbro-Peray
LHLaura Haefliger
Laura Haefliger
LTLaurène Tardieu
Laurène Tardieu
BGBoris Guiu
Boris Guiu
Thermal ablation of malignant liver tumors resulted in near-zero 90-day procedure-related mortality and a 3% major complication rate across 4149 patients in 49 prospective randomized or cohort studies.

14 January 2022 in Obstetrics & Gynecology International Journal
Verified
Journal Article
Open access
PDF file
QVQuoc Duy Vo
Quoc Duy Vo
TMThierry Molteni
Thierry Molteni
PPPatrique Oliveira Santos Patrique
Patrique Oliveira Santos Patrique
ENElodie Niasme
Elodie Niasme
LHLaura Haefliger
Laura Haefliger
Most breast cancers are diagnosed by conventional breast imaging which includes mammography, ultrasound and MRI. However, CT is an often overlooked modality in the detection and diagnosis of breast cancer. Incidental findings of breast cancer by CT are not so rare. This article aims to aware radiologists and gynaecologists to the potential of breast cancer detection with CT. In this brief review of the literature, we will discuss the morphological characteristics of breast tumours on CT and the imaging mangement of suspicious lesions discovered on CT.