In this study, nanospinels of MnFe₂O₄ were synthesized by a rapid method of microwave-assisted combustion technique for the removal of total chromium from real industrial wastewater. Nanoparticles of MnFe₂O₄ were characterized by X-ray diffraction and scanning electron microscopy. The removal of total chromium from real industrial wastewater, which was taken from galvanotechnic industry, using of nanospinel MnFe₂O₄ was investigated. The effects of adsorbent dosage, contact time, and initial concentrations on total chromium removal from wastewater were studied using the real wastewater. Optimal conditions were found for total chromium removal. Chromium removal and adsorption capacity of MnFe₂O₄ nanoparticles (NPs) were achieved as 59.35% and 89.18 mg/g, respectively. In addition, other optimum conditions of adsorbent dosage and contact time were found as 1.5 g/L and 120 min in this study, respectively. The removal of total chromium using MnFe₂O₄ NPs was fitted with Freundlich isotherm and pseudo-second-order kinetic models. The results indicated that MnFe₂O₄ nanospinels are suitable adsorbents for the removal of total chromium from industrial wastewater.