Background: IgA nephropathy (IgAN) is a leading cause of renal failure, characterized by significant clinical and pathological heterogeneity. Accurate subtype classification remains challenging due to overlapping clinical manifestations and the multidimensional nature of data. Traditional methods often fail to fully capture IgAN’s complexity, limiting their clinical applicability. This study introduces MAL-Net, a deep learning framework for multi-label classification of IgAN subtypes, leveraging multidimensional clinical data and incorporating sensor-based inputs such as laboratory indices and symptom tracking. Methods: MAL-Net integrates Long Short-Term Memory (LSTM) networks with Multi-Head Attention (MHA) mechanisms to effectively capture sequential and contextual dependencies in clinical data. A memory network module extracts features from clinical sensors and records, while the MHA module emphasizes critical features and mitigates class imbalance. The model was trained and validated on clinical data from 500 IgAN patients, incorporating demographic, laboratory, and symptomatic variables. Performance was evaluated against six baseline models, including traditional machine learning and deep learning approaches. Results: MAL-Net outperformed all baseline models, achieving 91% accuracy and an AUC of 0.97. The integration of MHA significantly enhanced classification performance, particularly for underrepresented subtypes. The F1-score for the Ni-du subtype improved by 0.8, demonstrating the model’s ability to address class imbalance and improve precision. Conclusions: MAL-Net provides a robust solution for multi-label IgAN subtype classification, tackling challenges such as data heterogeneity, class imbalance, and feature interdependencies. By integrating clinical sensor data, MAL-Net enhances IgAN subtype prediction, supporting early diagnosis, personalized treatment, and improved prognosis evaluation.

Video portrait segmentation is essential for intelligent sensing systems, including human-computer interaction, autonomous navigation, and augmented reality. However, dynamic video environments introduce significant challenges, such as temporal variations, occlusions, and computational constraints. This study introduces RVM+, an enhanced video segmentation framework based on the Robust Video Matting (RVM) architecture. By incorporating Convolutional Gated Recurrent Units (ConvGRU), RVM+ improves temporal consistency and captures intricate temporal dynamics across video frames. Additionally, a novel knowledge distillation strategy reduces computational demands while maintaining high segmentation accuracy, making the framework ideal for real-time applications in resource-constrained environments. Comprehensive evaluations on challenging datasets show that RVM+ outperforms state-of-the-art methods in both segmentation accuracy and temporal consistency. Key performance indicators such as MIoU, SAD, and dtSSD effectively verify the robustness and efficiency of the model. The integration of knowledge distillation ensures a streamlined and effective design with negligible accuracy trade-offs, highlighting its suitability for practical deployment. This study makes significant strides in intelligent sensor technology, providing a high-performance, efficient, and scalable solution for video segmentation. RVM+ offers potential for applications in fields such as augmented reality, robotics, and real-time video analysis, while also advancing the development of AI-enabled vision sensors.