Fan-Xuan Nie

Mr. Fan-Xuan Nie


Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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26 April 2023 in Antioxidants
Verified
Journal Article
Open access
PDF file
FNFan-Xuan Nie
Fan-Xuan Nie
LLLili Liu
Lili Liu
JCJiamin Cui
Jiamin Cui
YZYuquan Zhao
Yuquan Zhao
DZDawei Zhang
Dawei Zhang
MYMingli Yan
Mingli Yan
Oligomeric Proanthocyanidins (OPCs), as a class of compounds widely found in plants, are particularly abundant in grapes and blueberries. It is a polymer comprising many different monomers, such as catechins and epicatechins. The monomers are usually linked to each other by two types of links, A-linkages (C-O-C) and B-linkages (C-C), to form the polymers. Numerous studies have shown that compared to high polymeric procyanidins, OPCs exhibit antioxidant properties due to the presence of multiple hydroxyl groups. This review describes the molecular structure and natural source of OPCs, their general synthesis pathway in plants, their antioxidant capacity, and potential applications, especially the anti-inflammatory, anti-aging, cardiovascular disease prevention, and antineoplastic functions. Currently, OPCs have attracted much attention, being non-toxic and natural antioxidants of plant origin that scavenge free radicals from the human body. This review would provide some references for further research on the biological functions of OPCs and their application in various fields.

10 March 2025 in Biology
Verified
Journal Article
Open access
PDF file
SWShiwei Wang
Shiwei Wang
ZFZhang Fanli
Zhang Fanli
YZYilin Zhu
Yilin Zhu
FNFan-Xuan Nie
Fan-Xuan Nie
YZYi-Lin Zhu
Yi-Lin Zhu
XQXie Qijun
Xie Qijun
Brassica napus L. is a vital oil crop and exhibits notable salt tolerance, making the enhancement of this trait crucial for cultivation in saline soils. Uncovering its underlying mechanism may further heighten the salt tolerance of B. napus. In this study, we conducted a genome-wide analysis of the Root Meristem Growth Factor (RGF) gene family in Brassica species and identified BnaRGF8 as a key regulator of salt tolerance. Under 200 mM NaCl treatment, all RGF genes were induced, with BnaRGF8 showing the greatest upregulation. This response was consistently observed across 10 genotypes, indicating a universal trend in B. napus. Functional characterization revealed that chemically synthesized BnaRGF8 alleviated salt-induced growth inhibition by restoring primary root elongation and lateral root formation. Additionally, BnaRGF8 preserved membrane integrity and maintained cell division under salt stress, establishing itself as a novel anti-salt peptide in B. napus.