Sender Herschorn

Dr. Sender Herschorn


Research Focus & Metrics

Academic Career Length

29Years (1998-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 December 2009 in Neurourology and Urodynamics
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Journal Article
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SHSender Herschorn
Sender Herschorn
HBHomero Bruschini
Homero Bruschini
CCCraig Comiter
Craig Comiter
PGPhilippe Grise
Philippe Grise
THTomas Hanus
Tomas Hanus
CICommittee of the International Consultation on Incontinence
Committee of the International Consultation on Incontinence
Aims: The committee was charged with the responsibility of reviewing and evaluating all published data relating to surgical treatment of male urinary incontinence since the previous consultation in 2004.Methods: Articles from peer‐reviewed journals, abstracts from scientific meetings, and literature searches by hand and electronically formed the basis of this review. The articles were evaluated using Levels of Evidences adapted by the ICUD from the Oxford Centre for Evidence Based Medicine. The Recommendations for Care were based on the level of evidence and discussed among the committee members to reach consensus. The incontinence problems were classified according to their etiology, that is, either primarily sphincter or bladder related.Results: Specialist evaluation of the patient is primarily a clinical approach with history, frequency‐volume chart, physical examination, and post‐void residual urine. Other investigations such as radiographic imaging of the lower urinary tract, cystoscopy, and urodynamic studies can provide important information for the clinician. For stress incontinence of various etiologies the artificial urinary sphincter (AUS) has the longest record of satisfactory results. Consideration must be given to the need for revisions for mechanical breakdown, erosion/infection, and recurrent incontinence, as well as cost. Sling procedures are increasingly being reported to have good outcomes for mild to moderate incontinence. Injectable agents have not shown durable results but newer technologies such as volume‐adjustable balloons have shown favorable early results. Incontinence following cystectomy with neobladder and pelvic trauma has been treated most commonly with the AUS.Conclusions: Although the literature is replete with well‐done cohort studies, there is a need for prospective randomized clinical trials. Recommendations for trials include standardized workup and outcome measures and complete reporting of adverse events and long‐term results. Further research is also needed to elucidate the mechanism of post‐prostatectomy incontinence. Neurourol. Urodynam. 29: 179–190, 2010.

1 June 2011 in Journal of Urology
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Journal Article
Closed access
SHSender Herschorn
Sender Herschorn
JGJerzy Gajewski
Jerzy Gajewski
KEKaren Ethans
Karen Ethans
JCJacques Corcos
Jacques Corcos
KCKevin Carlson
Kevin Carlson
SRSidney Radomski
Sidney Radomski
We determined the efficacy of onabotulinumtoxinA for neurogenic detrusor overactivity secondary to spinal cord injury or multiple sclerosis. In a prospective, double-blind, multicenter study 57 patients 18 to 75 years old with neurogenic detrusor overactivity secondary to spinal cord injury or multiple sclerosis and urinary incontinence (defined as 1 or more occurrences daily) despite current antimuscarinic treatment were randomized to onabotulinumtoxinA 300 U (28) or placebo (29) via cystoscopic injection at 30 intradetrusor sites, sparing the trigone. Patients were offered open label onabotulinumtoxinA 300 U at week 36 and followed a further 6 months while 24 each in the treatment and placebo groups received open label therapy. The primary efficacy parameter was daily urinary incontinence frequency on 3-day voiding diary at week 6. Secondary parameters were changes in the International Consultation on Incontinence Questionnaire and the urinary incontinence quality of life scale at week 6. Diary and quality of life evaluations were also done after open label treatment. The mean daily frequency of urinary incontinence episodes was significantly lower for onabotulinumtoxinA than for placebo at week 6 (1.31 vs 4.76, p <0.0001), and for weeks 24 and 36. Improved urodynamic and quality of life parameters for treatment vs placebo were evident at week 6 and persisted to weeks 24 to 36. The most common adverse event in each group was urinary tract infection. In adults with antimuscarinic refractory neurogenic detrusor overactivity and multiple sclerosis onabotulinumtoxinA is well tolerated and provides clinically beneficial improvement for up to 9 months.

16 December 2009 in BJU International
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Journal Article
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SHSender Herschorn
Sender Herschorn
SSSteven Swift
Steven Swift
ZGZhonghong Guan
Zhonghong Guan
MCMartin Carlsson
Martin Carlsson
JMJon D. Morrow
Jon D. Morrow
JGJason Gong
Jason Gong

1 October 2007 in BJU International
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Journal Article
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SHSender Herschorn
Sender Herschorn
JGJerzy Gajewski
Jerzy Gajewski
JSJane Schulz
Jane Schulz
JCJacques Corcos
Jacques Corcos

1 March 2014 in Urology
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Journal Article
Closed access
SHSender Herschorn
Sender Herschorn
SESean Elliott
Sean Elliott
MCMichael Coburn
Michael Coburn
HWHunter Wessells
Hunter Wessells
LZLeonard Zinman
Leonard Zinman

17 October 2011 in BJU International
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Journal Article
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BWBlayne K. Welk
Blayne K. Welk
SHSender Herschorn
Sender Herschorn