Tobacco use remains a major global public health concern and a leading cause of preventable morbidity and mortality. Nicotine dependence is prevalent worldwide and contributes substantially to phys...

This chapter explores a wide range of smoking cessation strategies, emphasising the importance of both pharmacological and behavioural interventions in addressing nicotine addiction. It discusses various treatment options, including nicotine replacement therapy (NRT), electronic cigarettes (ECs), cognitive behavioural therapy (CBT), motivational interviewing (MI), and other appropriate behavioural intervention approaches. Additionally, emerging digital health solutions, such as smartphone apps, telemedicine, and text-message services, are reviewed for their potential to support smoking cessation efforts. The importance of public awareness campaigns and peer support is emphasised, as well as personalised treatment plans and the integration of multiple strategies to increase cessation success. Lastly, it stresses the need for continued research, particularly in adapting interventions to diverse populations and leveraging technology for broader reach.