Peyman Mirghaderi

Dr. Peyman Mirghaderi

orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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10 April 2022 in Journal of Orthopaedic Surgery and Research
Verified
Journal Article
Open access
PDF file
PMPeyman Mirghaderi
Peyman Mirghaderi
SSSadula Sharifpour
Sadula Sharifpour
AMAlireza Moharrami
Alireza Moharrami
NANegar Ahmadi
Negar Ahmadi
RMRangarirai Makuku
Rangarirai Makuku
SMSeyed Mohammad Javad Mortazavi
Seyed Mohammad Javad Mortazavi
Background: Templating is a preoperative planning procedure that improves the efficiency of the surgical process and reduces postoperative complications of total hip arthroplasty (THA) by improving the precision of prediction of prosthetic implant size. This study aimed to evaluate the accuracy of the preoperative cup and stem size digital 2D templating of THA with mediCAD® software and find the factors that influence the accuracy, such as indication for surgery, patients’ demographics, implant brand, and the assessors’ grade of education. Methods: We retrospectively retrieved 420 patient template images of all patients who underwent THA between March 2018 and March 2021. Templating of all included images was processed using mediCAD® software a day before surgery by a newcomer physician to hip arthroplasty course (PGY-2 orthopedic resident or hip surgery fellow). Preoperative templating cup and stem sizes were compared with the actual inserted implant sizes. Result: After excluding ineligible patients, this study included 391 patients, 193 (49.4%) males and 198 (50.6%) females with a mean age of 43.3 ± 14.9. The average cup sizes predicted before and after surgery were 52.12 ± 14.28 and 52.21 ± 15.05 respectively, and the mean delta cup size (before and after surgery) was 2.79 ± 2.94. The delta stem size before and after surgery has a mean value of 1.53 ± 1.49. The acetabular cup components, measured within ± 0, ± 1, and ± 2 sizes, were 28.9%, 63.9%, 83.1% accurate, respectively. The femoral stem design component measured within ± 0, ± 1, and ± 2 sizes were 27.2%, 61.0%, 78.6% accurate, respectively. Wagner Cone® stem brand, DDH patients, and females showed significantly higher accuracy of stem size templating. Revision THA has the lowest accuracy in terms of cup size templating. The compression of accuracy rate between resident and fellow revealed no significant differences. Also, no significant difference was detected between the accuracy of templating performed in the first months with the second months of the arthroplasty course period. Conclusion: Our study showed that under mentioned condition, templating using mediCAD® has acceptable accuracy in predicting the sizes of femoral and acetabular components in THA patients. Digital software like mediCAD® remains favorable because of the short learning curve, user-friendly features, and low-cost maintenance, leading to level-up patient care and THA efficacy. Further studies are necessary for clarifying the role of the assessor’s experience and expertise in THA preoperative templating. Level of evidence: Level III (retrospective observational study).

1 January 2023 in Journal of Experimental Orthopaedics
Verified
Journal Article
Open access
PDF file
AMAlireza Moharrami
Alireza Moharrami
PMPeyman Mirghaderi
Peyman Mirghaderi
NZNima Hoseini Zare
Nima Hoseini Zare
MMMir Mansour Moazen‐Jamshidi
Mir Mansour Moazen‐Jamshidi
MEMazaher Ebrahimian
Mazaher Ebrahimian
SMSeyed Mohammad Javad Mortazavi
Seyed Mohammad Javad Mortazavi
Purpose: Pelvic obliquity (PO) has not been extensively investigated, and there is no gold standard for measurement. The PO is essential for surgeons in planning hip arthroplasty, which includes the restoration of leg length discrepancy (LLD). We aimed to establish a normative range of PO angles by measuring healthy individuals without musculoskeletal disorders.Methods: Our study included 134 consecutive cases (70 females) referred to our institution between April 2020 and September 2021 for non‐orthopedic problems. Patients were screened for normal gait and posture using the visual observation method (VOM) and the Modified Gait Abnormality Rating Scale (GARS‐M). In standing standard radiographs, the PO angle was measured as the angle between the horizontal plane and the inter‐teardrop line.Results: Patients' mean age and Body Mass Index (BMI) were 39.7 ± 16.8 and 22.3 ± 3.1, respectively. PO angles did not follow a normal distribution, with a median (IQR) of 2.0° (0.9°—3.1°). According to the Wilcoxon one‐sample test, the median PO angle differed significantly from zero (P < 0.001). The PO angle did not differ significantly between males and females (2° vs. 2°, P = 0.46), nor did it correlate significantly with age (P = 0.24). Considering the 95% percentile of PO angles was 5.6°, this range (0°—5.6°) was regarded as a normative value.Conclusion: Normative values for PO in the normal healthy population range from 0° to 5.6°, with a median value of 2.0°. The PO angle was independent of age and sex and differed significantly from 0°. Slight pelvic obliquity may be normal, and physicians should not always assume that it is caused by pain, scoliosis, or weakness of the abductors.Level of evidence: III.

30 August 2022 in Journal of Experimental Orthopaedics
Verified
Journal Article
Open access
PDF file
PMPeyman Mirghaderi
Peyman Mirghaderi
ZVZahra Valizadeh
Zahra Valizadeh
KSKimia Shadman
Kimia Shadman
TLThibault Lafosse
Thibault Lafosse
LOLeila Oryadi‐Zanjani
Leila Oryadi‐Zanjani
MNMohammad Hossein Nabian
Mohammad Hossein Nabian
Purpose: Despite substantial animal evidence, cell therapy in humans remains in its infancy. The purpose of this study was to examine the potential therapeutic effects and safety of cell therapy in the treatment of tendon disorders.Methods: According to the PRISMA guideline, a systematic review was performed on clinical studies concerning cell therapy in tendon disorders. A comprehensive search including the 5 databases of MEDLINE, Embase, Scopus, Web of Science, and Cochrane Library until December 2021 was carried out and associated with hand searching. The quality of the eligible studies was assessed using the tools suggested by Cochrane recommendations. Qualitative synthesis was performed in 2 tables and discussed separately for rotator cuff, elbow, patella, Achilles, and gluteal tendons.Results: Through 6017 records, 22 studies were included in the qualitative synthesis, including 658 patients. All the studies administered autologous cells, except one that used allogenic adipose‐derived mesenchymal stem cells (Allogenic AD‐MSC). Almost all studies demonstrated the safety of cell injection in their follow‐up period with no serious side effects or immunologic reactions, with only a few related minor adverse events in some cases.The included studies showed the effectiveness of cell injection in tendinopathies of different sites, rotator cuff, elbow, patella, Achilles, and gluteal tendons. Among the rotator cuff studies, 4 comparative studies claimed that cell therapy is a more efficient treatment with a lower retear rate and pain level compared to the control group. However, one study found no differences between the groups. No controlled study has been performed on elbow tendinopathies, but 5 case series demonstrated the effectiveness of cell injection in elbow tendon disorders. For Achilles tendinopathies, only one randomized controlled trial (RCT) found that both cell therapy and control groups showed significant pain reduction and functional improvement with no statistical differences at the 6 months follow‐up, but the cell therapy group had improved faster at earlier follow‐ups. Patellar tendinopathy was studied in 2 RCTs, one did not show a significant difference and the other showed superior improvement compared to controls.Conclusion: Cell therapy showed promising results and the available evidence suggests that it is safe at several sites of tendon disease. Based on available evidence, cell therapy should be suggested in specific conditions at each site. To approve cell therapy for tendon diseases, randomized clinical trials are required with a large sample size and long‐term follow‐ups.Level of evidence: IV

5 December 2022 in Arthroplasty Today
Verified
Journal Article
Open access
HBHoma Bahrami
Homa Bahrami
AMAlireza Moharrami
Alireza Moharrami
PMPeyman Mirghaderi
Peyman Mirghaderi
SMSeyed Mohammad Javad Mortazavi
Seyed Mohammad Javad Mortazavi
We examined the effect of low-level laser therapy (LLLT) and Bioptron light therapy on pain and function following primary total knee arthroplasty. A single-center, single-surgeon, prospective randomized clinical trial was performed with 3 groups of 15 patients: LLLT (804 nm), light (Bioptron; Bioptron AG, Wollerau, Switzerland), and controls. Range of motion (ROM), visual analog scale pain, opiate consumption (oxycodone in milligrams), knee swelling, and the Knee Society Score (KSS) were assessed before the surgery and on postoperative day 2, postoperative day 3, month 3, and month 12 after the operation. The preoperative scores were similar between groups. A higher ROM was observed with the LLLT group at all follow-ups except at the 12-month follow-up (3-month ROM: 116.8° vs 104.0° vs 92.3°; P < .001). The knee swelling at 3 months was similar between the LLLT and light groups (2.1 cm), which was lower than that in controls (2.1 cm, P < .001). Furthermore, visual analog scale pain decreased more in the LLLT group than in other groups (8.5 vs 7.2 vs 6.0 points) at 3 months (P = .04) but was similar at 12 months (P > .05). Also, the LLLT group consumed fewer opiate painkillers during the first month (48.3 vs 60.3 mg of oxycodone, P = .02). In the LLLT group, the KSS at 3 and 12 months and the KSS function score at 3 months exceeded minimally clinically important differences (P < .05). In the early stages of recovery after total knee arthroplasty, LLLT and Bioptron light therapy could be helpful to control immediate and acute knee pain and swelling, reduce the need for opioids, improve ROM and functional scores, and improve recovery. Therapeutic level I.

21 July 2022 in International Orthopaedics
Verified
Journal Article
Closed access
PDF file
AMAlireza Moharrami
Alireza Moharrami
PMPeyman Mirghaderi
Peyman Mirghaderi
NHNima Hoseini-Zare
Nima Hoseini-Zare
MKMohammad Hasan Kaseb
Mohammad Hasan Kaseb
SMSeyed Mir Mansour Moazen-Jamshidi
Seyed Mir Mansour Moazen-Jamshidi
SMSeyed Mohammad Javad Mortazavi
Seyed Mohammad Javad Mortazavi

12 April 2022 in Arthroplasty Today
Verified
Journal Article
Open access
PMPeyman Mirghaderi
Peyman Mirghaderi
SBSoroush Baghdadi
Soroush Baghdadi
MSMaryam Salimi
Maryam Salimi
SSSeyyed Hossein Shafiei
Seyyed Hossein Shafiei
Alternative scientometric measures have introduced a novel view of the scientific literature. This study aimed to identify the top 50 most-cited recent articles in the field of knee and hip arthroplasty, characterize their traditional and alternative scientometric measures, and determine the relationship between traditional and alternative scientometric measures. The 50 most-cited articles with the term "arthroplasty" in the title that were published between 2015 and 2019 were retrieved from the Scopus database. Alternative scientometric parameters such as Altmetric Attention Score (AAS) from Altmetrics bookmarklet (Altmetrics.com) were retrieved. Scientometric variables such as journal impact factor, first author H-index, and keywords were also extracted. The 50 most-cited papers accrued 7955 total citations, with a mean of 159.10 ± 56.4 citations per article. The overall mean AAS across the papers was 63.4 ± 164.8. The mean first author's H-index was 23.8 ± 18.9. Papers published in 2017 and 2018 had a significantly higher mean AAS than those published in 2015 and 2016 (35.1 vs 22.5, P = .009). Citation count was weakly correlated with the AAS (correlation coefficient = 0.379, P = .009). Also, AAS had significant correlations with the journal's impact factor (P < .001). We found that the AAS was highest in more recently published papers, while citation count had the opposite trend. The AAS was significantly correlated with the journal's impact factor and citation count, but the correlation is weak. This suggests that the alternative scientometric measures are complementary to, and not substitutes for, complement traditional measures such as citation count and impact factor.