Prof. Jason L. Parsons is Chair of Radiobiology at the University of Birmingham. He acquired a BSc (Hons) in Medical Biochemistry (1996) and a PhD in Biochemistry (2000) from the University of Birmingham. He then worked as a Postdoctoral Research Scientist at the Cancer Research UK Paterson Institute for Cancer Research in Manchester (2000-2002), and at the MRC Radiation and Genome Stability Unit in Harwell (2003-2007). He subsequently worked as a Senior Investigator Scientist at the CRUK/MRC Gray Institute for Radiation Oncology and Biology at the University of Oxford, UK (2008-2012). Prof. Parsons established his independent research group at the University of Liverpool (2012-2022), before moving to Birmingham in 2023. He is currently Chair of the Association for Radiation Research (ARR). As a radiation biologist, Prof Parsons' research is focused on the biochemistry, molecular and cellular biology of ionising radiation (radiotherapy). His main interests lie in examining the biology of radiation of different ionisation densities, particularly proton beam therapy and other forms of high-linear-energy-transfer (LET) radiation, and largely their impact on the signalling and processing of DNA damage. His research is centred on models of head and neck squamous cell carcinoma (HNSCC) and other radioresistant tumours and on identifying optimal strategies including combination with targeted drugs/inhibitors to enhance the sensitivity of these cancers to low/high-LET radiotherapy.
Research Keywords & Expertise
DNA damage
DNA Repair
Radiation Biology
proton beam therapy
Base excision repair
Fingerprints
58%
DNA damage
40%
DNA Repair
33%
Base excision repair
10%
proton beam therapy
Short Biography
Prof. Jason L. Parsons is Chair of Radiobiology at the University of Birmingham. He acquired a BSc (Hons) in Medical Biochemistry (1996) and a PhD in Biochemistry (2000) from the University of Birmingham. He then worked as a Postdoctoral Research Scientist at the Cancer Research UK Paterson Institute for Cancer Research in Manchester (2000-2002), and at the MRC Radiation and Genome Stability Unit in Harwell (2003-2007). He subsequently worked as a Senior Investigator Scientist at the CRUK/MRC Gray Institute for Radiation Oncology and Biology at the University of Oxford, UK (2008-2012). Prof. Parsons established his independent research group at the University of Liverpool (2012-2022), before moving to Birmingham in 2023. He is currently Chair of the Association for Radiation Research (ARR). As a radiation biologist, Prof Parsons' research is focused on the biochemistry, molecular and cellular biology of ionising radiation (radiotherapy). His main interests lie in examining the biology of radiation of different ionisation densities, particularly proton beam therapy and other forms of high-linear-energy-transfer (LET) radiation, and largely their impact on the signalling and processing of DNA damage. His research is centred on models of head and neck squamous cell carcinoma (HNSCC) and other radioresistant tumours and on identifying optimal strategies including combination with targeted drugs/inhibitors to enhance the sensitivity of these cancers to low/high-LET radiotherapy.