Alexandros Makris

Dr. Alexandros Makris

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Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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21 August 2013 in Journal of Anesthesia
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Journal Article
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AMAlexandros Makris
Alexandros Makris
APAlexandros Piperopoulos
Alexandros Piperopoulos
IKIosifina Karmaniolou
Iosifina Karmaniolou

4 November 2023 in Regional Anesthesia & Pain Medicine
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KEKariem El-Boghdadly
Kariem El-Boghdadly
PAProf. Dr. Eric Albrecht
Prof. Dr. Eric Albrecht
MWMorné Wolmarans
Morné Wolmarans
EMEdward Mariano
Edward Mariano
SKSandra Kopp
Sandra Kopp
NENabil M Elkassabany
Nabil M Elkassabany
Background Inconsistent nomenclature and anatomical descriptions of regional anesthetic techniques hinder scientific communication and engender confusion; this in turn has implications for research, education and clinical implementation of regional anesthesia. Having produced standardized nomenclature for abdominal wall, paraspinal and chest wall regional anesthetic techniques, we aimed to similarly do so for upper and lower limb peripheral nerve blocks. Methods We performed a three-round Delphi international consensus study to generate standardized names and anatomical descriptions of upper and lower limb regional anesthetic techniques. A long list of names and anatomical description of blocks of upper and lower extremities was produced by the members of the steering committee. Subsequently, two rounds of anonymized voting and commenting were followed by a third virtual round table to secure consensus for items that remained outstanding after the first and second rounds. As with previous methodology, strong consensus was defined as ≥75% agreement and weak consensus as 50%–74% agreement. Results A total of 94, 91 and 65 collaborators participated in the first, second and third rounds, respectively. We achieved strong consensus for 38 names and 33 anatomical descriptions, and weak consensus for five anatomical descriptions. We agreed on a template for naming peripheral nerve blocks based on the name of the nerve and the anatomical location of the blockade and identified several areas for future research. Conclusions We achieved consensus on nomenclature and anatomical descriptions of regional anesthetic techniques for upper and lower limb nerve blocks, and recommend using this framework in clinical and academic practice. This should improve research, teaching and learning of regional anesthesia to eventually improve patient care.

1 January 2013 in Journal of Surgical Research
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Journal Article
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KKKonstantinos Konstantopoulos
Konstantinos Konstantopoulos
AMAlexandros Makris
Alexandros Makris
AMAlexandra Moustaka
Alexandra Moustaka
IKIosifina Karmaniolou
Iosifina Karmaniolou
GKGeorgios Konstantopoulos
Georgios Konstantopoulos
AMArgyro Mela
Argyro Mela

5 March 2018 in Journal of Anesthesia
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Journal Article
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DTDimitra Tziona
Dimitra Tziona
MPMarianna Papaioannou
Marianna Papaioannou
AMArgyro Mela
Argyro Mela
SPStyliani Potamianou
Styliani Potamianou
AMAlexandros Makris
Alexandros Makris

1 September 2020 in Journal of Clinical Anesthesia
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Journal Article
Closed access
MDMaria Diakomi
Maria Diakomi
MPMarianna Papaioannou
Marianna Papaioannou
GGGeorge Georgoudis
George Georgoudis
EAErifili Argyra
Erifili Argyra
AMArgyro Mela
Argyro Mela
AMAlexandros Makris
Alexandros Makris

23 July 2019 in Medicina
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ESEleftheria Soulioti
Eleftheria Soulioti
ATAthanasia Tsaroucha
Athanasia Tsaroucha
AMAlexandros Makris
Alexandros Makris
MKMaria Koutsaki
Maria Koutsaki
ESEirini Sklika
Eirini Sklika
AFArgyro Fassoulaki
Argyro Fassoulaki
Background and objectives: Brachial plexus block is commonly used in shoulder surgery, as it provides satisfactory surgical conditions and adequate postoperative pain control. However, there are contradictory reports regarding the addition of tramadol to the injected regional anesthetic solution. We performed a prospective randomized study to evaluate the effectiveness of tramadol as an adjuvant to ropivacaine during interscalene brachial plexus block and assess its impact on the opioid consumption and the early postoperative pain in patients that underwent shoulder surgery. Materials and Methods: Eighty patients scheduled for elective shoulder surgery and anesthesia via interscalene brachial plexus block were randomly divided into two groups. In group A (n = 40), a solution of 40 mL of ropivacaine 0.5% and 2 mL (100 mg) of tramadol was administered during the brachial plexus block, while in group B (n = 40), a solution of 40 mL of ropivacaine 0.5% and 2 mL NaCl 0.9% (placebo) was administered. The effectiveness and duration of sensory and motor blocks were recorded in both groups. The sensory block was assessed recording the loss of sensation to pin prick test over the skin distribution of the axillary, radial, and musculocutaneous nerves. The motor block was assessed using the modified 3-point Bromage score (0–2 points). Cumulative morphine consumption and pain, using the Visual Analog Scale (VAS), were evaluated in both groups at 2, 4, 8, and 24 h after surgery. Results: Sensory block onset was achieved earlier in group A than in group B (5.21 ± 3.15 minutes (min) vs. 7.1 ± 4.51 min, p = 0.029). The motor block onset was similar between the two groups (13.08 ± 6.23 min vs. 13.28 ± 6.59 min; p = 0.932). The duration of the sensory block was longer in group A as compared to group B (13 ± 2.3 h vs. 12 ± 2.8 h; p = 0.013). The duration of the motor block did not present any difference between the groups (10 ± 2.2 h vs. 10 ± 2.8 h; p = 0.308). Differences in morphine administration were not significant at 2, 4, and 8 h, however, morphine consumption was found to be decreased in group A 24 h postoperatively A (p = 0.04). The values of VAS were similar at 2, 4, and 8 h, however, they were lower in group A at 24 h (p < 0.013). Conclusions: Combined regional administration of tramadol and ropivacaine during interscalene brachial plexus block improves the time of onset and the duration of the sensory block, while it is associated with reduced morphine consumption during the first 24 h after shoulder surgery.