In 1989, I obtained my Ph.D. under the supervision of Dr. Yamasaki at the International Agency for Research on Cancer (Lyon, France), where I studied the involvement of gap junctions in carcinogenesis. Then, I pursued my post-doctoral studies in the laboratory of Dr. Gilula at the Scripps Research Institute (La Jolla, California), where I confirmed the loss of gap junctional intercellular communication as a characteristic of cancer cells. In 1991, I went back to Dr. Yamasaki’s laboratory before joining, in 2000, Dr. Giaume’s group at Collège de France (Paris, France) to study the effect of inflammation on astrocytic gap junctions. The same year, I was appointed as professor of physiology at the University of Poitiers (France), where I focused my research activities on the role of gap-junction proteins (connexins) in brain tumor progression and invasion.