Recent developments in cervical cancer treatment have highlighted concerns about minimally invasive surgery. Our team explored an innovative approach that

Aim: The aim of our study is to determine the prevalence of intracardiac echogenic focus and to investigate the possible association of congenital heart diseases in risky pregnancies. Materials and Methods: A total of 380 pregnant women who were in the 17th to 36th week of gestation were included in our study. The patients were classified as low risk and high risk groups according to various referral reasons such as any drug usage, presence of chromosomal or fetal anomalies, number and characteristics of previous pregnancies, congenital or acquired heart diseases in the family and presence of family history. Results: Based on the selective criteria 134 (35.26%) pregnant women were classified as the low-risk group while 246 (64.74%) pregnant were classified as the high-risk group. Maternal diabetes (13.16%) was the most common reason for referral in the high-risk group. However, in the low-risk pregnancies, lack of good image of the fetal heart by ultrasonography was the major reason for referral (21.05%). Intracardiac echogenic foci were detected in total of 77 (20.26%) cases, which of 68 (50.75%) cases were in the low-risk group and 9 (3.66%) cases were in the high-risk group. Left ventricular echogenic foci were detected in 59 (44.03%) fetuses in low-risk pregnancies and 4 (1.63%) fetuses in high-risk pregnancies (p=0.001). Additionally, only one fetus in low-risk pregnancy and one fetus in high-risk pregnancy had echogenic foci in one of the ventricles with congenital heart diseases. Conclusion: In conclusion, we found the prevalence of intracardiac echogenic foci in low-risk pregnancies as 50.75% which was higher than in high-risk pregnancies. This can be attributed to ethnicity, tertiary hospital referrals, relatively low number of patients and other associated factors. Additionally, in our study, no correlation was found between congenital heart diseases and intracardiac echogenic foci in both low- and high-risk pregnancies.

Gestational diabetes mellitus (GDM) requires effective management during pregnancy and careful postpartum follow-up. Initially managed through dietary adjustments and exercise, some cases may require insulin therapy to maintain blood glucose levels within normal ranges. Postpartum, women diagnosed with GDM should undergo glucose testing at 6-12 weeks after delivery to screen for persistent diabetes. Lifestyle modifications, including regular physical activity and healthy eating, remain essential to prevent the development of type 2 diabetes in the future. Monitoring and support from healthcare providers are critical to ensure optimal maternal health and reduce the risk of complications in subsequent pregnancies.

Background:Hyperemesis gravidarum (HG) is a clinical condition characterized by systemic inflammation and maternal malnutrition. However, the role of a composite index integrating both inflammatory and nutritional parameters for identifying the degree of metabolic stress, as reflected by ketonuria severity, has not been investigated. This study aimed to evaluate the association between the Naples Prognostic Score (NPS), a composite index on inflammatory and nutritional biomarkers, and ketonuria severity in patients with HG.Methods:This retrospective cross-sectional study included 241 pregnant women hospitalized with a diagnosis of HG between October 2022 and October 2025. Patients were stratified into mild-to-moderate (n = 134) and severe (n = 107) ketonuria groups based on urine ketone levels. The NPS was calculated using the neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), serum albumin, and total cholesterol levels. Group comparisons, correlation analyses, receiver operating characteristic (ROC) curve analysis, and multivariable logistic regression analyses were performed.Results:Age, body mass index (BMI), and obstetric history were comparable between groups. Neutrophil count, NLR, and NPS were significantly higher in the severe ketonuria group. In contrast, lymphocyte count, LMR, serum albumin, and total cholesterol were significantly lower, reflecting a greater inflammatory and nutritional burden in patients in the severe ketonuria group. Among all variables tested, NPS demonstrated the strongest correlation with ketonuria severity (r = 0.845; p < 0.001). ROC curve analysis revealed that NPS had excellent discriminatory performance in identifying severe ketonuria (area under the ROC curve [AUC] = 0.939; sensitivity 90.65%, and specificity 93.28% at a cutoff value ≥3). In the multivariable logistic regression analysis, an NPS ≥3 (odds ratio [OR] = 110.261; 95% confidence interval [CI]: 42.724–284.560; p < 0.001) and total cholesterol level (OR = 0.981; p = 0.037) were independently associated with severe ketonuria. The wide CI reflects model instability and shared variance between the NPS and its components; therefore, the point estimate should not be interpreted as a stable measure of effect size.Conclusions:At admission, NPS demonstrated a strong cross-sectional association with the severity of ketonuria and excellent discriminatory performance for identifying severe ketonuria. However, because both measures were obtained simultaneously, these findings should be interpreted as reflecting a concurrent association rather than true prospective prediction.

Bilgi üreten Üniversiteler, mütemadiyen güncelledikleri bilgi ile eğitimlerini sürdürmekte; dolayısıyla bir yandan toplumun refahına katkı sağlarken diğer yandan da kendi geleceklerini güvence altına almaktadır. Bilginin güncellenmesi yeni ve derinlikli araştırmalarla mümkündür. Derinlikli araştırma ise alan hakimiyetine ve bilimsel araştırma yeteneğine bağlıdır. Bu imkanı sağlayacak olanlar ise biritecrübeli bilim insanı, diğeri de alan hakimiyetini kolaylaştıracak olan temel bilgi kitaplarıdır.Dünyanın Covid-19 pandemisiyle uğraştığı bir dönemde hekimlerimizin yükü katlanarak artmıştır. Görev ve sorumluluk bilinciyle kendilerini korumayı ikinci planda değerlendiren hekimlerimizin, bu yoğun iş yükü altında akademik metin üretimine zaman ayırmaları ve tıp camiasında başvuru kitabı olarak işlev üstlenecek böyle bir eseri literatüre kazandırmaları her türlü takdirin üstündedir. Eserinortak bir çalışmanın ürünü olarak gün yüzüne çıkmış olması, daha nitelikli eserlerin habercisi olarak değerlendirdiğimiz için, gelecek açısından bizi ümitledirmektedir.