Daniel Vu

Daniel Vu

orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 April 2021 in American Journal of Ophthalmology
Verified
Journal Article
Closed access
DVDaniel Vu
Daniel Vu
JSJustin Stoler
Justin Stoler
ARAdam L. Rothman
Adam L. Rothman
TCTa Chen Chang
Ta Chen Chang

20 March 2025 in Medicina
Verified
Journal Article
Open access
PDF file
MMMousa Moradi
Mousa Moradi
SKSaber Kazeminasab
Saber Kazeminasab
DVDaniel Vu
Daniel Vu
ASAllison R. Soneru
Allison R. Soneru
AFAsahi Fujita
Asahi Fujita
NZNazlee Zebardast
Nazlee Zebardast
Background and Objectives: Glaucoma (GL) classification is crucial for early diagnosis and treatment, yet relying solely on stand-alone models or International Classification of Diseases (ICD) codes is insufficient due to limited predictive power and inconsistencies in clinical labeling. This study aims to improve GL classification using stacked weight-based machine learning models. Materials and Methods: We analyzed a subset of 33,636 participants (58% female) with 340,444 visual fields (VFs) from the Mass Eye and Ear (MEE) dataset. Five clinically relevant GL detection models (LoGTS, UKGTS, Kang, HAP2_part1, and Foster) were selected to serve as base models. Two multi-layer perceptron (MLP) models were trained using 52 total deviation (TD) and pattern deviation (PD) values from Humphrey field analyzer (HFA) 24-2 VF tests, along with four clinical variables (age, gender, follow-up time, and race) to extract model weights. These weights were then utilized to train three meta-learners, including logistic regression (LR), extreme gradient boosting (XGB), and MLP, to classify cases as GL or non-GL. Results: The MLP meta-learner achieved the highest performance, with an accuracy of 96.43%, an F-score of 96.01%, and an AUC of 97.96%, while also demonstrating the lowest prediction uncertainty (0.08 ± 0.13). XGB followed with 92.86% accuracy, a 92.31% F-score, and a 96.10% AUC. LR had the lowest performance, with 89.29% accuracy, an 86.96% F-score, and a 94.81% AUC, as well as the highest uncertainty (0.58 ± 0.07). Permutation importance analysis revealed that the superior temporal sector was the most influential VF feature, with importance scores of 0.08 in Kang’s and 0.04 in HAP2_part1 models. Among clinical variables, age was the strongest contributor (score = 0.3). Conclusions: The meta-learner outperformed stand-alone models in GL classification, achieving an accuracy improvement of 8.92% over the best-performing stand-alone model (LoGTS with 87.51%), offering a valuable tool for automated glaucoma detection.

30 November 2024 in American Journal of Ophthalmology
Verified
Journal Article
Closed access
AFAsahi Fujita
Asahi Fujita
DVDaniel Vu
Daniel Vu
KAKanza Aziz
Kanza Aziz
TCTa Chen Chang
Ta Chen Chang
ICIn Young Chung
In Young Chung
ALAlice Lorch
Alice Lorch

6 September 2023 in Ophthalmology Glaucoma
Verified
Journal Article
Closed access
DVDaniel Vu
Daniel Vu
TETobias Elze
Tobias Elze
JMJoan W. Miller
Joan W. Miller
ALAlice C. Lorch
Alice C. Lorch
DVDeborah K. VanderVeen
Deborah K. VanderVeen
FLFlora Lum
Flora Lum

24 May 2023 in Ophthalmology
Verified
Journal Article
Closed access
ACAnjalee Choudhury
Anjalee Choudhury
ESEliza Stuart
Eliza Stuart
JSJustin Stoler
Justin Stoler
DVDaniel Vu
Daniel Vu
TCTa Chen Chang
Ta Chen Chang

24 June 2025 in Ophthalmology
Verified
Journal Article
Closed access
AFAsahi Fujita
Asahi Fujita
DVDaniel Vu
Daniel Vu
ARAdam L. Rothman
Adam L. Rothman
DFDavid S. Friedman
David S. Friedman
NZNazlee Zebardast
Nazlee Zebardast
ALAlice Lorch
Alice Lorch