Berberine is a promising agent for modulating the intestinal microbiota, playing a crucial role in human health homeostasis. This natural compound promotes the growth of beneficial bacteria such as Bacteroides, Bifidobacterium, and Lactobacillus while reducing harmful bacteria such as Escherichia coli. Clinical and preclinical studies demonstrate that Berberine helps regulate T2D and metabolic disorders, improves blood glucose levels during T2D, and reduces lipid profile and chronic inflammation, especially when combined with probiotics. Berberine represents a promising adjuvant therapy for inflammatory diseases, particularly intestinal disorders, due to its multifaceted actions of inhibiting proinflammatory cytokines and pathways during IBS, IBD, and UC and its modulation of gut microbiota and/or enhancement of the integrity of the intestinal epithelial barrier. This review establishes the basis for future treatment protocols with berberine and fully elucidates its mechanisms.

Actualmente existen vacíos de conocimientos respecto a la conducta alimentaria e indicadores de salud mental como bienestar psicológico. El objetivo del presente estudio fue evaluar la asociación entre las conductas alimentarias de riesgo, variables antropométricas y bienestar psicológico en adolescentes del noroeste de México. Se realizó un estudio cuantitativo con diseño no experimental, transversal y analítico. Se utilizó un muestreo por conveniencia, seleccionando estudiantes de segundo grado de secundaria de una institución pública del noroeste de México. Las CAR se evaluaron mediante el Cuestionario Breve de Conductas Alimentarias de Riesgo y el Eating Attitudes Test (EAT-40), mientras que el Bienestar Psicológico se midió con la Escala de Bienestar Psicológico para Adolescentes. Asimismo, se realizaron mediciones antropométricas estandarizadas. El análisis incluyó estadística descriptiva. Se emplearon pruebas t de Student y chi cuadrado para comparaciones por sexo, así como correlaciones de Pearson, considerando significancia estadística de p<0.05. El 37.87% presentaron riesgo moderado o alto de CAR según CBCAR y 45.46% riesgo moderado o alto según EAT40. En bienestar psicológico 28.78% se ubicó en nivel leve o bajo (18.18%). Se encontró una correlación negativa significativa entre CAR y BP, no se encontraron correlaciones de CAR o BP con las variables antropométricas. Los resultados revelaron un porcentaje sustancial de adolescentes que presenta riesgo moderado o alto de CAR. Además, se encontró una correlación negativa entre CAR y BP, enfatizando el impacto de la salud mental en los hábitos alimentarios.

Objective: Compare nutrient intake based on categories of disordered eating behaviors in adolescents. Materials and methods: The present study has a non-experimental cross-sectional analytical design, with a quantitative approach. Sampling was carried out at convenience. The brief questionnaire of risky eating behaviors used by Padrós-Blázquez et al. was used, and weight and height were determined to form the body mass index. The 24-hour reminder dietary survey was also applied to calculate the percentage of adequacy and determine nutrient intake, the percentages of adequacy (%AD) were calculated, and the nutrient ranges were taken according to the Recommended Dietary Allowances (RDA), for sugar the recommendation of the Nutrition Committee of the European Society of Pediatric Gastroenterology, Hepatology and Nutrition was used. An overadequate AD was considered when the %AD was >110%, adequate with a range of 110 - 90%, low <90%. Results: A combined prevalence of risky eating behaviors of 37.88% was found, with medium and high risk (25.76% and 12.12% respectively). A significant difference was found in the intake of vitamin A, ascorbic acid, iron, and folate among the categories, being higher in the low-risk group compared to the medium and high-risk groups. Additionally, overadequate %ADs were found for sugar, energy, protein, potassium, sodium, and carbohydrates, while the lowest %ADs were for folate, fiber, and phosphorus. Conclusions: Nutrient intake differs according to the REB category, and key micronutrients for adolescence are involved in low intake, which can cause negative health effects. Keywords: Nutrients; Eating behavior; Adolescents.