Chemical Biology; Antibodies and Immunity; Innovative targets and drugs; Reproductive biology. 1. Mechanism of sperm function regulation, and discovery of novel active compounds and their applications; 2. Novel PTMs antigen preparation, antibody production of high quality, epitope research and multi-omics applications; 3. Novel targets and lead compounds of coronavirus, especially Targeted Protein Degrader technologies, including PROTACs, Molecular glues and Hydrophobic tag.