Giada Mai

Dr. Giada Mai


Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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9 April 2025 in Medicina
Verified
Journal Article
Open access
PDF file
AMAlberto Morello
Alberto Morello
SCStefano Colonna
Stefano Colonna
EBEnrico Lo Bue
Enrico Lo Bue
GCGiulia Chiari
Giulia Chiari
GMGiada Mai
Giada Mai
FCFabio Cofano
Fabio Cofano
Background and Objectives: Robotic-assisted surgery (RS) has progressively emerged as a promising technology in modern thoracolumbar spinal surgery, offering the potential to enhance accuracy and improve clinical outcomes. To date, the benefits of robot-assisted techniques in thoracolumbar spinal surgery remain controversial. The objective of this study was to assess the efficacy and safety of RS compared to fluoroscopy-assisted surgery (FS) in spinal fusion procedures. Materials and Methods: In accordance with the PRISMA guidelines, a systematic review and meta-analysis was conducted, using REVMAN V5.3 software. The review protocol was registered in the Prospective Register of Systematic Reviews (PROSPERO) website with the following registration number: CRD42024567193. Results: Eighteen studies were included in the meta-analysis with a total of 1566 patients examined. The results demonstrated a worse accuracy in FS in cases with major violations of the peduncular cortex (D–E grades, according to Gertzbein’s classification) [(odds ratio (OR) 0.47, 95%-CI 0.28 to 0.80, I2 0%]. In addition, a lower complication rate was shown in the RS group compared to the FS group, specifically regarding the need for surgical revision due to screw mispositioning (OR 0.28-CI 0.17 to 0.48, I2 98%). Conclusions: Advantages of robot-assisted techniques were demonstrated in terms of postoperative complications, revision surgery rates, and the accuracy of screw placement. While RS represents a valuable and promising technological advancement in thoracolumbar spinal surgery, future studies are needed to further explore its advantages in thoracolumbar spinal surgery and to identify which spinal surgical approach has greater advantages when using the robot.

13 October 2026 in European Spine Journal
Verified
Journal Article
Open access
PDF file
SCStefano Colonna
Stefano Colonna
JTJacopo Talarico
Jacopo Talarico
GMGiada Mai
Giada Mai
LCLuca Ceroni
Luca Ceroni
AFAlessandro Fiumefreddo
Alessandro Fiumefreddo
FCFabio Cofano
Fabio Cofano
Objective: Urinary dysfunction is an underexplored component of postoperative morbidity in spinal ependymomas. This study aimed to characterize longitudinal urinary and fecal outcomes, bladder-management trajectories, and predictors of early dysfunction and long-term catheter dependency following surgical resection. Methods: A retrospective cohort study of adult patients undergoing resection of spinal ependymomas was performed (2018–2024). Urinary and fecal outcomes were assessed at baseline, discharge, and 12 months. Bladder management was longitudinally assessed at discharge, 3, 6, and 12 months. Univariable logistic regression was used to identify predictors of postoperative urinary dysfunction and catheter dependency. Results: Fifty-five adult patients undergoing surgical resection for spinal ependymoma were included. Urinary dysfunction increased from 1.8% at baseline to 20.0% at discharge, then decreased to 12.7% at 12 months, mainly due to urinary retention. Fecal dysfunction remained uncommon throughout follow-up. Among patients with postoperative urinary retention ( n = 10), bladder-management trajectories demonstrated progressive recovery over time, with six patients showing a lower level of catheter dependency at 12 months, four remaining unchanged, and no patients worsening. Most favorable transitions occurred within the first 6 months after surgery. Notably, no patient requiring an indwelling catheter at discharge remained dependent on it at 12-month follow-up. Subtotal resection (OR 6.34, p = 0.012) and intraoperative neurophysiological alterations (SSEP: OR 17.50, p < 0.001; MEP: OR 16.88, p < 0.001) were associated with postoperative urinary dysfunction. Histological subtype and tumor location were not associated with early postoperative urinary dysfunction but showed a descriptive relationship with longitudinal bladder-management outcomes. Conclusion: Urinary dysfunction is common after spinal ependymoma surgery but often improves over time. Early indwelling catheter dependency should not be considered a definitive poor prognostic sign, while extent of resection and intraoperative neurophysiological alterations appear to identify patients at increased risk of early postoperative urinary dysfunction.