We aimed to quantify rates of waning immunity after measles vaccination from seroprevalence data collected in a study of a population with high vaccination coverage and a fixed vaccination schedule. Data were collected during a national survey (the Immunological Survey) carried out in the Slovak Republic in 2018. The average rate of waning immunity against measles after the first dose of measles, mumps, and rubella (MMR) vaccine (ages 1.5–10 years) was 9.7% per year from the geometric mean titer value of 2,634 mUI/mL. The average waning rate after the second dose of MMR vaccine (ages 10–33 years) was significantly lower: 4.8% per year from the lower geometric mean titer of 1,331 mUI/mL. This decline in antibody levels suggests that vaccine-induced protection may be compromised and results in an increase in the proportion of seronegative/borderline individuals. These outcomes may provide a valuable source for critical assessment of direct and indirect effects of MMR vaccination.

Analysis of subnational regional differences in frequency of selected risk factors of overweight and obesity in adolescents in Slovakia. Cross-sectional study. Health Behaviour in School-aged Children is an international cross-sectional questionnaire study using the standard protocol to create representative samples of adolescents. We analyse subnational regional differences in the occurrence of selected risk factors of overweight and obesity among 10-12-year-old (n = 4194) and 14-16-year-old (n = 3806) respondents of a survey conducted in Slovakia in 2022. Overweight and obesity dominated especially in the regions with the Hungarian minority among boys aged 10-12 years (29.2 %) and 14-16 years (34.0 %). Consumption of energy (24.9 % of girls and 29.9 % of boys) and sweetened (25.0 % of girls and 27.1 % of boys) drinks dominated among 14-16-year-old respondents in the poverty regions with socio-economic problems. Skipping breakfast was most widespread among 14-16-year-old girls from regions with a Hungarian minority (72.6 %). Insufficient physical activity was most frequent among 10-12-year-old respondents, namely, in the poverty regions (85.0 % of girls) and the Hungarian minority (79.6 % of boys) regions. The differences also remained significant after weighting for a possible confounding effect of family socioeconomic status. The regional social environment is associated with selected aspects of adolescents' behaviour related to overweight and obesity, namely, the poverty regions and Hungarian minority environments, and can be considered as an independent determinant regardless of a family background.

Background/Objectives: This study analyzed data on the actual timing of the first and second doses of the Measles, Mumps, and Rubella (MMR) vaccination in Slovakia according to the vaccination schedule. Methods: Histograms were constructed using immunological survey data on MMR vaccination conducted in Slovakia in 2018. Results: For the first dose (2560 individuals), 83.4% of them were vaccinated timely (15th–18th month, mostly in the 16th month), while 13.8% of them were delayed. For the second dose (1061 individuals), 72.7% of vaccinations were timely (11th year), and 23.2% were delayed. There was a bimodal distribution of the timing of the administration of the second dose, with peaks at the beginning of the 11th year and at the turn of the 11th and 12th year. Conclusions: The unexpected shape of the histograms suggests that ambiguous interpretations of the vaccination schedule may be one of the causes of vaccination delays.

The aim of our meta-analysis was to determine the global prevalence of burnout among physicians measured by the Copenhagen Burnout Inventory (CBI). A meta-analysis performed following the PRISMA guidelines. PubMed, Scopus, and Web of Science were searched for trials on the prevalence of physician's burnout syndrome. A literature search (October-November 2025) was performed, and pooled prevalence was estimated using a random-effects model. Joanna's Briggs Institute (JBI) quality assessment tool was used to evaluate the risk of bias. Cochrane I-squared test was used to evaluate the heterogeneity among studies. The meta-analysis was performed using IBM SPSS Statistics software (version 29.0.2.0.). Thirty-nine cross-sectional studies containing 17,963 physicians were finally included in the analysis. The global prevalence of burnout was 52% (95% CI: 46%-57%). Pre-pandemic studies from Europe yielded a pooled prevalence of 34% (95% CI: 23%-46%), compared with 47% (95% CI: 34%-61%) during the COVID-19 era. In Asia, the pooled prevalence increased from 55% (95% CI: 46%-64%) before the pandemic to 66% (95% CI: 57%-74%) during the pandemic. A large number of physicians were identified as having moderate-high burnout levels. The findings of this analysis highlight the need for policy measures aimed at enhancing the working environment of healthcare professionals and mitigating burnout. The protocol was registered on PROSPERO (CRD420251177705). Not applicable.